[CAS NO. 133803-81-3] Hydroxy-PEG2-(CH2)2-Boc
PRODUCTS SPECIFICATIONS [133803-81-3]
DESCRIPTION [133803-81-3]
Overview
| MDL | MFCD20926380 |
|---|---|
| Molecular Weight | 234.29 |
| Molecular Formula | C11H22O5 |
| SMILES | O=C(OC(C)(C)C)CCOCCOCCO |
Summary
Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196) [1] . Hydroxy-PEG2-(CH2)2-Boc is also a PROTAC linker that can be used in the synthesis of PROTACs .
IC50 & Target
|
Non-cleavable |
PEGs |
Alkyl/ether |
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Liquid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Pure form | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
