[CAS NO. 195514-23-9] AP1867
PRODUCTS SPECIFICATIONS [195514-23-9]
DESCRIPTION [195514-23-9]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 693.78 |
| Molecular Formula | C38H47NO11 |
| SMILES | COC1=CC=C(CC[C@@H](OC([C@@H]2CCCCN2C([C@H](C3=CC(OC)=C(OC)C(OC)=C3)CC)=O)=O)C4=CC=CC(OCC(O)=O)=C4)C=C1OC |
Summary
AP1867 is a synthetic FKBP12 F36V -directed ligand [1] .
IC50 & Target
FKBP [1]
In Vitro
AP1867 associates with wild-type FKBP (K d = 67 nM) [2] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 100 mg/mL ( 144.14 mM ; ultrasonic and warming and heat to 60°C)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 1.4414 mL | 7.2069 mL | 14.4138 mL |
| 5 mM | 0.2883 mL | 1.4414 mL | 2.8828 mL |
| 10 mM | 0.1441 mL | 0.7207 mL | 1.4414 mL |
-
1.
-
2.
Add each solvent one by one: 10% DMSO >> 90% corn oil
Solubility: ≥ 2.08 mg/mL (3.00 mM); Clear solution
References
