[CAS NO. 2222981-71-5]  MACglucuronidelinker-1

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PRODUCTS SPECIFICATIONS [2222981-71-5]

Store
Catalog
HY-44221
Brand
MCE
CAS
2222981-71-5

DESCRIPTION [2222981-71-5]

Overview

MDL-
Molecular Weight897.90
Molecular FormulaC42H47N3O17S
SMILESO=C(OC)[C@@H](O1)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC2=CC=C(COC(NCCS(=O)(C)=O)=O)C=C2NC(CN(C(OCC3C4=C(C5=C3C=CC=C5)C=CC=C4)=O)C)=O

For research use only. We do not sell to patients.

Summary

MAC glucuronide linker-1 is a claevable ADC linker for antibody-drug-conjugations (ADCs) [1] .


IC50 & Target

Glycosidase Cleavable

Cleavable


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)


Solvent & Solubility

In Vitro:

DMSO : ≥ 200 mg/mL ( 222.74 mM )

* "≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1137 mL 5.5685 mL 11.1371 mL
5 mM 0.2227 mL 1.1137 mL 2.2274 mL
10 mM 0.1114 mL 0.5569 mL 1.1137 mL
* Please refer to the solubility information to select the appropriate solvent.