[CAS NO. 229977-57-5] MACglucuronidelinker-2

Name: MACglucuronidelinker-2
Brand: Arctom Scientific
SKU: HY-44222

Ships within

Stock

Price

Qty

Total

$0.00

Please click "REQUEST A QUOTE" button if you need other sizes or custom synthesis

request a quote

If there is no stock, or you need other sizes or custom synthesis, please:

PRODUCTS SPECIFICATIONS [229977-57-5]

Store

Catalog

HY-44222

Brand

MCE

CAS

229977-57-5

MDL	MFCD31715406
Molecular Weight	455.41
Molecular Formula	C20H25NO11
SMILES	O=C(OC)[C@@H](O1)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC2=CC=C(CO)C=C2N

For research use only. We do not sell to patients.

MAC glucuronide linker-2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) ^[1] .

Cleavable

Glycosidase Cleavable

Solid

Room temperature in continental US; may vary elsewhere.

4°C, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

In Vitro:

DMSO : 200 mg/mL ( 439.16 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 5 mg/mL (10.98 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 5 mg/mL (10.98 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 5 mg/mL (10.98 mM); Clear solution

* All of the co-solvents are available by MCE.