| MDL | - |
|---|---|
| Molecular Weight | 331.41 |
| Molecular Formula | C18H25N3O3 |
| SMILES | O=C(N1C(OC2=CC(C3CCN(C)CC3)=CC=C12)=O)NCC(C)C |
Acid Ceramidase-IN-1 is a potent and oral bioavailable acid ceramidase (AC, ASAH-1) inhibitor (hAC IC 50 =0.166 μM). Acid Ceramidase-IN-1 has excellent brain penetration in mice [1] .
Solid
Room temperature in continental US; may vary elsewhere.
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
DMSO : 50 mg/mL ( 150.87 mM ; ultrasonic and warming and heat to 60°C)
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 3.0174 mL | 15.0871 mL | 30.1741 mL |
| 5 mM | 0.6035 mL | 3.0174 mL | 6.0348 mL |
| 10 mM | 0.3017 mL | 1.5087 mL | 3.0174 mL |