[CAS NO. 39445-21-1] Elastase, Porcine pancreas
PRODUCTS SPECIFICATIONS [39445-21-1]
DESCRIPTION [39445-21-1]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 25898.13 |
| Molecular Formula | C1135H1759N331O346S10 |
| SMILES | - |
Summary
In Vivo
Elastase from porcine pancreas induces emphysema in hamsters [3] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
Sealed storage, away from moisture
| Powder | -80°C | 2 years |
|---|---|---|
| -20°C | 1 year |
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H 2 O : 50 mg/mL ( 1.93 mM ; ultrasonic and adjust pH to 9 with NaOH)
H 2 O : 1 mg/mL ( 0.04 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 0.0386 mL | 0.1931 mL | 0.3861 mL |
| 5 mM | --- | --- | --- |
| 10 mM | --- | --- | --- |
References
- [1] Shotton DM, et, al. Amino-acid sequence of porcine pancreatic elastase and its homologies with other serine proteinases. Nature. 1970 Feb 28;225(5235):802-6.
- [2] Teshima T, et, al. A new class of heterocyclic serine protease inhibitors. Inhibition of human leukocyte elastase, porcine pancreatic elastase, cathepsin G, and bovine chymotrypsin A alpha with substituted benzoxazinones, quinazolines, and anthranilates. J Biol Chem. 1982 May 10;257(9):5085-91.
- [3] Stone PJ, et, al. Induction and exacerbation of emphysema in hamsters with human neutrophil elastase inactivated reversibly by a peptide boronic acid. Am Rev Respir Dis. 1990 Jan;141(1):47-52.
