[CAS NO. 552-66-9]  Daidzin

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PRODUCTS SPECIFICATIONS [552-66-9]

Store
Catalog
HY-N0018
Brand
MCE
CAS
552-66-9

DESCRIPTION [552-66-9]

Overview

MDLMFCD00017466
Molecular Weight416.38
Molecular FormulaC21H20O9
SMILESOC1=CC=C(C2=COC(C=C(O[C@H]3[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O3)C=C4)=C4C2=O)C=C1

For research use only. We do not sell to patients.


Summary

Daidzin is an isoflavone that has anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities; directly inhibits mitochondrial aldehyde dehydrogenase 2 (IC50 = 80 nM) and is an effective anti-dipsotropic isoflavone.


Clinical Trial

NCT Number Sponsor Condition Start Date Phase
NCT02309801 Parc de Salut Mar|Ministerio de Sanidad, Servicios Sociales e Igualdad
Healthy
July 2012 Phase 1

Appearance

Solid



Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : ≥ 34 mg/mL ( 81.66 mM )

* "≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4017 mL 12.0083 mL 24.0165 mL
5 mM 0.4803 mL 2.4017 mL 4.8033 mL
10 mM 0.2402 mL 1.2008 mL 2.4017 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.08 mg/mL (5.00 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: 2.08 mg/mL (5.00 mM); Suspended solution; Need ultrasonic

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.08 mg/mL (5.00 mM); Clear solution

* All of the co-solvents are available by MCE.


Synonyms

4H-1-Benzopyran-4-one, 7-(β-D-glucopyranosyloxy)-3-(4-hydroxyphenyl)-
Daidzin
7-(β-D-Glucopyranosyloxy)-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Daidzein 7-glucoside
7,4′-Dihydroxyisoflavone 7-glucoside
Daidzoside
Daidzein 7-O-glucoside
NPI 031D
Daidzine