[CAS NO. 59-05-2] Methotrexate

Name: Methotrexate
Brand: Arctom Scientific
SKU: HY-14519

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PRODUCTS SPECIFICATIONS [59-05-2]

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Catalog

HY-14519

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MCE

CAS

59-05-2

DESCRIPTION [59-05-2]

Overview

MDL	MFCD00150847
Molecular Weight	454.44
Molecular Formula	C20H22N8O5
SMILES	NC1=NC(N)=C2C(N=CC(CN(C)C3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=N1

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23 Publications Citing Use of MCE

Summary

Methotrexate (Amethopterin), an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase , thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia) ^[1] ^[2] ^[3] .

IC50 & Target

Traditional Cytotoxic Agents

In Vivo

Methotrexate (Amethopterin) reduces thymus and spleen indices of mice. Methotrexate markedly decreases white blood cells, thymic and splenic lymphocytes at dose ≥5 mg/kg. However, there is a significant difference between the treatment plus control group and the model group (p<0.01). The combination of grape seed proanthocyanidins and Siberian ginseng eleutherosides obviously diminishes the effects of Methotrexate exposure on indices of thymus and spleens in mice ^[2] .
Methotrexate (MTX) (2 mg/kg; i.p.; once in a week for 5 weeks) is effective in Freund's complete adjuvant-induced arthritis. The combination of Methotrexate (1 mg/kg; i.p.; once in a week for 5 weeks) and Curcumin (30 mg/kg and 100 mg/kg, thrice a week for 5 weeks; i.p.) shows a significant anti-arthritic action and protection from hematological toxicity ^[4] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase
NCT01995201	Hoffmann-La Roche	Rheumatoid Arthritis	September 2013	Phase 3
NCT01746992	Ruijin Hospital	ALK-negative Anaplastic Large Cell Lymphoma\|Peripherial T Cell Lymphoma,Not Otherwise Specified\|Angioimmunoblastic T Cell Lymphoma\|Enteropathy Associated T Cell Lymphoma\|Hepatosplenic T Cell Lymphoma\|Subcutaneous Panniculitis Like T Cell Lymphoma	September 2012	Phase 4
NCT02054442	Radboud University Medical Center\|Merck Serono International SA\|Leiden University Medical Center\|Academisch Ziekenhuis Maastricht\|Erasmus Medical Center\|Medisch Spectrum Twente\|Medical Center Haaglanden\|Elisabeth-TweeSteden Ziekenhuis\|Medical Centre Leeuwarden	Squamous Cell Carcinoma of the Head and Neck	August 2016	Phase 1\|Phase 2
NCT00006455	Gustave Roussy, Cancer Campus, Grand Paris	Lymphoma	November 26, 1999	Phase 3
NCT01158885	Therapeutic Advances in Childhood Leukemia Consortium\|Genzyme, a Sanofi Company	Minimal Residual Disease\|Leukemia, Lymphoblastic, Acute\|Leukemia, Myelogenous, Acute	August 2010	Phase 2
NCT00547521	Bristol-Myers Squibb	Rheumatoid Arthritis (RA)	December 2007	Phase 3
NCT01979536	National Cancer Institute (NCI)	Anaplastic Large Cell Lymphoma, ALK-Positive\|Ann Arbor Stage II Noncutaneous Childhood Anaplastic Large Cell Lymphoma\|Ann Arbor Stage III Noncutaneous Childhood Anaplastic Large Cell Lymphoma\|Ann Arbor Stage IV Noncutaneous Childhood Anaplastic Large Cell Lymphoma	November 8, 2013	Phase 2
NCT00381680	Children´s Oncology Group\|National Cancer Institute (NCI)	B-cell Childhood Acute Lymphoblastic Leukemia\|L1 Childhood Acute Lymphoblastic Leukemia\|L2 Childhood Acute Lymphoblastic Leukemia\|Intermediate Risk Recurrent Childhood Acute Lymphoblastic Leukemia	March 2007	Phase 3
NCT03852888	CHU de Reims	Rheumatoid Arthritis	November 14, 2018	Not Applicable
NCT01984099	University of the Philippines	Hydatidiform Mole	December 2011	Phase 3
NCT00372619	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia	March 2007	Phase 1\|Phase 2
NCT00343785	Fred Hutchinson Cancer Center\|National Heart, Lung, and Blood Institute (NHLBI)	Aplastic Anemia	February 2006	Phase 2
NCT00154336	Novartis Pharmaceuticals\|Novartis	Rheumatoid Arthritis	July 2004	Phase 2
NCT02885597	Cui xuejun\|Shanghai Yueyang Integrated Medicine Hospital\|Longhua Hospital\|Shanghai Guanghua Hospital of Integrated Traditional Chinese and Western Medicine\|Shanghai University of Traditional Chinese Medicine	Juanbi Pill\|Rheumatoid Arthritis	July 2018	Phase 2\|Phase 3
NCT01217814	Sanofi\|Regeneron Pharmaceuticals	Rheumatoid Arthritis	November 2010	Phase 2
NCT04579848	Diakonhjemmet Hospital\|Oslo University Hospital	Hand Osteoarthritis\|Erosive Osteoarthritis	August 12, 2021	Phase 4
NCT01876082	Institut Bergonié	Progressive Desmoids Tumors	September 18, 2012	Phase 2
NCT04095858	OncoImmune, Inc.	Hematopoietic Stem Cell Transplantation\|Acute Graft Versus Host Disease\|Acute Myeloid Leukemia\|Acute Lymphoblastic Leukemia\|Myelodysplastic Syndromes	January 5, 2021	Phase 3
NCT01120366	SURPRISE Study Group	Rheumatoid Arthritis	October 2009	Phase 4
NCT00494897	PETHEMA Foundation	Acute Lymphoblastic Leukemia	June 1996	Phase 4
NCT00866307	Children´s Oncology Group\|National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|Adult B Acute Lymphoblastic Leukemia\|Childhood B Acute Lymphoblastic Leukemia	February 23, 2009	Phase 1
NCT00045305	Eastern Cooperative Oncology Group\|National Cancer Institute (NCI)	Leukemia\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Neoplasms	May 2005	Phase 2
NCT04384692	Fred Hutchinson Cancer Center	Primary Myelofibrosis\|Secondary Myelofibrosis	December 18, 2020	Phase 2
NCT00243412	Genentech, Inc.	Rheumatoid Arthritis	August 2005	Phase 2
NCT00759811	Instituto de Cardiologia do Rio Grande do Sul	Heart Failure\|Myocardial Ischemia	December 2007	Phase 2\|Phase 3
NCT02523976	Institute of Hematology & Blood Diseases Hospital	Acute,Leukemia, Lymphoid	August 1, 2015	Phase 2
NCT04610476	University of Erlangen-Nürnberg Medical School	Psoriatic Arthritis\|Withdrawal\|Reduction	October 19, 2020	Phase 3
NCT00051311	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Hematologic Neoplasms	January 3, 2003	Phase 2
NCT00001256	National Institute of Allergy and Infectious Diseases (NIAID)\|National Institutes of Health Clinical Center (CC)	Inflammation\|Vasculitis\|Wegener´s Granulomatosis	March 1990	Phase 2
NCT04214626	Henan Cancer Hospital	Diffuse Large B Cell Lymphoma	January 2, 2020	Phase 2
NCT03103334	Crossject	Healthy	June 2014	Phase 1
NCT00002691	Memorial Sloan Kettering Cancer Center	Lymphoma	August 1995	Phase 2
NCT00141830	Wyeth is now a wholly owned subsidiary of Pfizer	Rheumatoid Arthritis	August 2005	Phase 2
NCT00369226	Dana-Farber Cancer Institute\|Brigham and Women´s Hospital\|Millennium Pharmaceuticals, Inc.	Hematologic Malignancies	August 2006	Phase 1\|Phase 2
NCT02706951	AbbVie	Rheumatoid Arthritis	March 23, 2016	Phase 3
NCT00577122	Indiana University\|Translational Breast Cancer Research Consortium	Estrogen Receptor-negative Breast Cancer\|Progesterone Receptor-negative Breast Cancer\|Recurrent Breast Cancer\|Stage IV Breast Cancer	July 2007	Phase 2
NCT02277444	Janssen Research & Development, LLC	Arthritis, Juvenile	December 17, 2014	Phase 3
NCT03643276	Martin Schrappe\|Deutsche Krebshilfe e.V., Bonn (Germany)\|University Hospital Schleswig-Holstein	Acute Lymphoblastic Leukemia, Pediatric	July 15, 2018	Phase 3
NCT00669890	New York Medical College	Acute Myeloid Leukemia\|Juvenile Myelomonocytic Leukemia\|Myelodysplastic Syndrome	May 2004	Phase 1
NCT00002471	Memorial Sloan Kettering Cancer Center	Leukemia\|Lymphoma	February 1990	Phase 2
NCT04136262	Guang´anmen Hospital of China Academy of Chinese Medical Sciences	Rheumatoid Arthritis	November 25, 2019	Phase 2\|Phase 3
NCT02829424	Assistance Publique Hopitaux De Marseille	Psoriasis	April 2016	Phase 4
NCT00445744	Fred Hutchinson Cancer Center\|National Heart, Lung, and Blood Institute (NHLBI)\|National Cancer Institute (NCI)	Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|Childhood Acute Myeloid Leukemia in Remission\|Childhood Myelodysplastic Syndromes\|de Novo Myelodysplastic Syndromes\|Essential Thrombocythemia\|Myelodysplastic Syndrome With Isolated Del(5q)\|Polycythemia Vera\|Previously Treated Myelodysplastic Syndromes\|Primary Myelofibrosis\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Childhood Acute Myeloid Leukemia\|Secondary Acute Myeloid Leukemia\|Secondary Myelodysplastic Syndromes\|Secondary Myelofibrosis\|Untreated Adult Acute Myeloid Leukemia\|Untreated Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies	December 2006	Not Applicable
NCT03147612	M.D. Anderson Cancer Center	Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Acute Lymphoblastic Leukemia\|Acute Myeloid Leukemia With BCR-ABL1\|Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Recurrent Acute Lymphoblastic Leukemia\|Refractory Acute Lymphoblastic Leukemia	February 8, 2018	Phase 2
NCT05583071	University of Cologne\|Incyte Corporation	Non-Hodgkin Lymphoma	January 2023	Phase 2
NCT02553018	Nordic Pharma SAS	Arthritis, Rheumatoid	September 2015	Phase 3
NCT00003934	National Cancer Institute (NCI)	Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Promyelocytic Leukemia (M3)\|Childhood Acute Promyelocytic Leukemia (M3)\|Untreated Adult Acute Myeloid Leukemia\|Untreated Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies	June 1999	Phase 3
NCT00030264	Children´s Hospital of Philadelphia	Neurofibromatosis Type 1\|Precancerous Condition	February 2001	Phase 2
NCT00526409	PETHEMA Foundation	Acute Lymphoblastic Leukemia	June 2005	Phase 4
NCT00198991	Goethe University\|Deutsche Krebshilfe e.V., Bonn (Germany)\|German Federal Ministry of Education and Research	Adult Acute Lymphocytic Leukemia	April 2003	Phase 4
NCT00521430	Asan Medical Center\|National Cancer Institute (NCI)	Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Nonmalignant Neoplasm\|Unspecified Adult Solid Tumor, Protocol Specific	April 2004	Not Applicable
NCT05036577	Huashan Hospital	Primary Central Nervous System Lymphoma	October 10, 2021	Phase 1
NCT00283985	University Hospital, Limoges	Lymphoma, Non-Hodgkin	February 2006	Phase 2
NCT00025636	German Hodgkin´s Lymphoma Study Group\|European Organisation for Research and Treatment of Cancer - EORTC\|EBMT Solid Tumors Working Party\|National Cancer Institute (NCI)	Lymphoma	July 2001	Phase 3
NCT00905073	Georgetown University	Type 1 Diabetes Mellitus	February 1990	Not Applicable
NCT00122382	Bristol-Myers Squibb	Rheumatoid Arthritis	July 2005	Phase 3
NCT00430118	University Hospital Schleswig-Holstein	Leukemia	July 2000	Phase 3
NCT04216524	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Blastic Plasmacytoid Dendritic Cell Neoplasm	May 29, 2020	Phase 2
NCT02897700	Shanghai Jiao Tong University School of Medicine\|Shanghai 10th People´s Hospital\|China-Japan Union Hospital, Jilin University\|Ganzhou City People´s Hospital	Breast Cancer	January 2013	Phase 1
NCT04965597	Fred Hutchinson Cancer Center\|Blood and Marrow Transplant Clinical Trials Network\|National Cancer Institute (NCI)\|National Marrow Donor Program\|National Heart, Lung, and Blood Institute (NHLBI)	Bone Marrow Failure Syndrome\|Congenital Amegakaryocytic Thrombocytopenia\|Congenital Pure Red Cell Aplasia\|Hereditary Sideroblastic Anemia\|Myeloid Neoplasms With Germline GATA2 Mutation\|Paroxysmal Nocturnal Hemoglobinuria\|Shwachman-Diamond Syndrome	April 19, 2022	Phase 2
NCT05503875	Second Affiliated Hospital, School of Medicine, Zhejiang University	Immunoclassification\|Psoriasis	January 1, 2023	Not Applicable
NCT00671034	Children´s Oncology Group\|National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|Adult B Acute Lymphoblastic Leukemia\|Childhood B Acute Lymphoblastic Leukemia	July 21, 2008	Phase 3
NCT02748785	Seoul National University Hospital	Arthritis, Rheumatoid	September 2015	Phase 4
NCT00005988	Dana-Farber Cancer Institute\|National Cancer Institute (NCI)	Graft Versus Host Disease\|Leukemia\|Lymphoma\|Myelodysplastic Syndromes\|Myeloma	February 2000	Phase 1
NCT01389076	University of Michigan Rogel Cancer Center\|GlaxoSmithKline	Follicular Lymphoma	July 2011	Phase 2
NCT00002571	Southwest Oncology Group\|National Cancer Institute (NCI)	Lymphoma	June 1994	Phase 2
NCT00586846	Memorial Sloan Kettering Cancer Center	Osteosarcoma	July 2003	Phase 2
NCT03779854	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Acute Biphenotypic Leukemia\|Acute Leukemia\|Acute Leukemia of Ambiguous Lineage\|Acute Lymphoblastic Leukemia\|Acute Undifferentiated Leukemia\|Allogeneic Hematopoietic Stem Cell Transplantation Recipient\|Blastic Plasmacytoid Dendritic Cell Neoplasm\|Blasts Under 25 Percent of Bone Marrow Nucleated Cells\|Blasts Under 5 Percent of Bone Marrow Nucleated Cells\|Mixed Phenotype Acute Leukemia\|Myelodysplastic Syndrome With Excess Blasts-1\|Myelodysplastic Syndrome With Excess Blasts-2	August 29, 2019	Phase 2
NCT00502996	Hoffmann-La Roche	Rheumatoid Arthritis	February 2006	Phase 3
NCT00361335	Centocor, Inc.\|Schering-Plough	Rheumatoid Arthritis	September 2006	Phase 3
NCT01185301	AbbVie (prior sponsor, Abbott)\|AbbVie	Early Rheumatoid Arthritis	October 2010	Phase 3
NCT01764997	Sanofi\|Regeneron Pharmaceuticals	Rheumatoid Arthritis	April 2013	Phase 3
NCT00313625	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Multiple Myeloma and Plasma Cell Neoplasm	September 2005	Phase 2
NCT01412879	Southwest Oncology Group\|National Cancer Institute (NCI)	Lymphoma	November 2011	Phase 2
NCT04737889	Henan Cancer Hospital	Primary Central Nervous System Lymphoma	January 13, 2021	Phase 2
NCT01373151	CSL Behring	Rheumatoid Arthritis	June 2011	Phase 2
NCT00517699	Hoffmann-La Roche	Lymphoma	September 2007	Phase 2
NCT01871649	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	Psoriatic Arthritis	August 2013	Phase 3
NCT00003593	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Neoplasms	June 1999	Phase 3
NCT05533372	ILAb Co., Ltd.	Healthy\|Rheumatoid Arthritis	October 10, 2022	Phase 1
NCT05292664	Andrew E. Place\|AbbVie\|Servier\|Children´s Cancer Research Fund\|University of Colorado, Denver\|Boston Children´s Hospital\|Dana-Farber Cancer Institute	Myelodysplastic Syndromes, de Novo\|Myelodysplastic Syndromes, Secondary\|Myelodysplastic Syndromes, Previously Treated\|Treatment-Related Acute Myeloid Leukemia\|Therapy-Related Myelodysplastic Syndrome\|Acute Lymphoblastic Leukemia, in Relapse\|Acute Lymphoblastic Leukemia With Failed Remission\|Lymphoblastic Lymphoma, in Relapse\|Lymphoblastic Lymphoma, Refractory\|Acute Leukemia of Ambiguous Lineage in Relapse\|Acute Leukemia of Ambiguous Lineage Not Having Achieved Remission	October 2022	Phase 1
NCT01034137	Hoffmann-La Roche	Rheumatoid Arthritis	January 2010	Phase 3
NCT03058471	Postgraduate Institute of Medical Education and Research	Early Chikungunya Arthritis	December 2016	Not Applicable
NCT01005758	Ohio State University Comprehensive Cancer Center\|National Cancer Institute (NCI)	Leukemia	January 2009	Phase 2
NCT00673920	Genentech, Inc.\|Roche Pharma AG	Rheumatoid Arthritis	April 24, 2008	Phase 3
NCT03535519	Juan Carlos Nieto\|Nordic Pharma SAS\|Hospital General Universitario Gregorio Marañon	Rheumatoid Arthritis	August 7, 2018
NCT03913559	St. Jude Children´s Research Hospital\|Pfizer	Acute Lymphoblastic Leukemia	May 14, 2019	Phase 2
NCT00209859	Hvidovre University Hospital	Rheumatoid Arthritis	October 1998	Phase 4
NCT00405275	US Department of Veterans Affairs\|Canadian Institutes of Health Research (CIHR)\|Rheumatoid Arthritis Investigational Network (RAIN)\|National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)\|VA Office of Research and Development	Rheumatoid Arthritis	July 2007	Not Applicable
NCT00002970	National Cancer Institute (NCI)\|Children´s Cancer Group	Recurrent Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood Lymphoblastic Lymphoma\|T-cell Childhood Acute Lymphoblastic Leukemia	June 1997	Phase 2
NCT00037115	MidAmerica Neuroscience Research Foundation at Rowe Neurology Institute\|Consultants in Neurology	Demyelinating Disorders\|Multiple Sclerosis\|Optic Neuritis\|Myelitis\|Neuritis	May 2002	Phase 4
NCT01177371	Case Comprehensive Cancer Center	Accelerated Phase Chronic Myelogenous Leukemia\|Adult Acute Lymphoblastic Leukemia in Remission\|Adult Acute Megakaryoblastic Leukemia (M7)\|Adult Acute Monoblastic Leukemia (M5a)\|Adult Acute Monocytic Leukemia (M5b)\|Adult Acute Myeloblastic Leukemia With Maturation (M2)\|Adult Acute Myeloblastic Leukemia Without Maturation (M1)\|Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With T(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With T(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With T(8;21)(q22;q22)\|Adult Acute Myelomonocytic Leukemia (M4)\|Adult Acute Promyelocytic Leukemia (M3)\|Adult Erythroleukemia (M6a)\|Adult Nasal Type Extranodal NK+T-cell Lymphoma\|Adult Pure Erythroid Leukemia (M6b)\|Anaplastic Large Cell Lymphoma\|Angioimmunoblastic T-cell Lymphoma\|Burkitt Lymphoma\|Childhood Acute Erythroleukemia (M6)\|Childhood Acute Lymphoblastic Leukemia in Remission\|Childhood Acute Megakaryocytic Leukemia (M7)\|Childhood Acute Monoblastic Leukemia (M5a)\|Childhood Acute Monocytic Leukemia (M5b)\|Childhood Acute Myeloblastic Leukemia With Maturation (M2)\|Childhood Acute Myeloblastic Leukemia Without Maturation (M1)\|Childhood Acute Myeloid Leukemia in Remission\|Childhood Acute Myelomonocytic Leukemia (M4)\|Childhood Acute Promyelocytic Leukemia (M3)\|Childhood Chronic Myelogenous Leukemia\|Childhood Myelodysplastic Syndromes\|Chronic Phase Chronic Myelogenous Leukemia\|Cutaneous B-cell Non-Hodgkin Lymphoma\|De Novo Myelodysplastic Syndromes\|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue\|Hepatosplenic T-cell Lymphoma\|Intraocular Lymphoma\|Nodal Marginal Zone B-cell Lymphoma\|Peripheral T-Cell Lymphoma\|Post-transplant Lymphoproliferative Disorder\|Previously Treated Myelodysplastic Syndromes\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Adult Burkitt Lymphoma\|Recurrent Adult Diffuse Large Cell Lymphoma\|Recurrent Adult Diffuse Mixed Cell Lymphoma\|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma\|Recurrent Adult Grade III Lymphomatoid Granulomatosis\|Recurrent Adult Hodgkin Lymphoma\|Recurrent Adult Immunoblastic Large Cell Lymphoma\|Recurrent Adult Lymphoblastic Lymphoma\|Recurrent Adult Non-Hodgkin Lymphoma\|Recurrent Adult T-cell Leukemia+Lymphoma\|Recurrent Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood Acute Myeloid Leukemia\|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma\|Recurrent Grade 1 Follicular Lymphoma\|Recurrent Grade 2 Follicular Lymphoma\|Recurrent Grade 3 Follicular Lymphoma\|Recurrent Mantle Cell Lymphoma\|Recurrent Marginal Zone Lymphoma\|Recurrent Mycosis Fungoides+Sezary Syndrome\|Recurrent Small Lymphocytic Lymphoma\|Refractory Multiple Myeloma\|Relapsing Chronic Myelogenous Leukemia\|Secondary Myelodysplastic Syndromes\|Small Intestine Lymphoma\|Splenic Marginal Zone Lymphoma\|Testicular Lymphoma\|Waldenstrom Macroglobulinemia	March 1988	Phase 2
NCT00354393	Case Comprehensive Cancer Center\|National Cancer Institute (NCI)	Malignant Mesothelioma	August 2002	Phase 2
NCT02867306	Astellas Pharma Global Development, Inc.\|Astellas Pharma Inc	Rheumatoid Arthritis	July 25, 2016	Phase 1
NCT01185288	AbbVie (prior sponsor, Abbott)\|AbbVie	Rheumatoid Arthritis	September 2010	Phase 4
NCT04516655	Fudan University	Central Nervous System Lymphoma	September 1, 2020	Phase 2
NCT00322101	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)\|National Heart, Lung, and Blood Institute (NHLBI)	Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome\|Acute Myeloid Leukemia+Transient Myeloproliferative Disorder\|Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|Childhood Acute Myeloid Leukemia in Remission\|Childhood Myelodysplastic Syndromes\|de Novo Myelodysplastic Syndromes\|Myelodysplastic Syndrome With Isolated Del(5q)\|Myelodysplastic+Myeloproliferative Neoplasm, Unclassifiable\|Previously Treated Myelodysplastic Syndromes\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Childhood Acute Myeloid Leukemia\|Secondary Acute Myeloid Leukemia\|Secondary Myelodysplastic Syndromes	January 2006	Phase 3
NCT00965653	Hoffmann-La Roche	Rheumatoid Arthritis	August 2009	Phase 1
NCT00989703	Galapagos NV	Healthy	September 2009	Phase 1
NCT00701129	Genzyme, a Sanofi Company\|Sanofi	Pompe Disease\|Glycogen Storage Disease Type II	October 2009	Phase 4
NCT03593759	Ottawa Heart Institute Research Corporation\|Canadian Institutes of Health Research (CIHR)	Cardiac Sarcoidosis\|Sarcoidosis	January 15, 2019	Phase 3
NCT02124226	Universita degli Studi di Catania	Low Dose Methotrexate in Severe Chronic Asthma	December 2021	Phase 3
NCT02342145	Affiliated hospital of guangxi medical university,china\|Union hospital of Fujian Medical University\|Zhongshan Hospital Xiamen University\|The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School\|Kunming general Hospital of Chengdu Military Region\|First Affiliated Hospital of Guangxi Medical University	Beta-Thalassemia Major	June 2014	Phase 4
NCT01248780	Centocor, Inc.\|Schering-Plough	Rheumatoid Arthritis	September 2010	Phase 3
NCT00609739	Masonic Cancer Center, University of Minnesota	Leukemia	June 1999	Phase 1\|Phase 2
NCT04899453	Peking Union Medical College Hospital	Primary Vitreoretinal Lymphoma	August 1, 2020	Phase 2
NCT04961801	Shin Mineishi\|Milton S. Hershey Medical Center	Lymphoma\|Leukemia	March 2022	Phase 1\|Phase 2
NCT00727987	Janssen Pharmaceutical K.K.\|Mitsubishi Tanabe Pharma Corporation	Rheumatoid Arthritis	May 2008	Phase 3
NCT02345850	National Heart, Lung, and Blood Institute (NHLBI)\|Blood and Marrow Transplant Clinical Trials Network\|National Cancer Institute (NCI)	Acute Leukemia\|Myelodysplasia	August 2015	Phase 3
NCT03360760	Peking University People´s Hospital	Osteosarcoma of Pelvis	August 1, 2018	Not Applicable
NCT00415935	Institute of Child Health	Juvenile Idiopathic Arthritis
NCT00779220	Chugai Pharmaceutical	Rheumatoid Arthritis	October 2008	Phase 2
NCT03163966	Rottapharm Biotech	Rheumatoid Arthritis, DMARD-naive and Early Disease Patients	October 5, 2017	Phase 2
NCT00742924	Children´s Oncology Group\|National Cancer Institute (NCI)	Sarcoma	August 2008	Phase 1
NCT01451515	St. Jude Children´s Research Hospital\|National University, Singapore	Lymphoblastic Lymphoma	May 25, 2012	Phase 2
NCT01188798	St. Jude Children´s Research Hospital	Acute Lymphoblastic Leukemia\|Acute Myelocytic Leukemia\|Chronic Myelocytic Leukemia\|Hodgkin´s Disease\|Myelodysplastic Syndrome	September 2010	Phase 3
NCT00002456	Fred Hutchinson Cancer Center	Graft Versus Host Disease\|Leukemia\|Lymphoma	May 1986	Phase 3
NCT00004686	The Cleveland Clinic\|FDA Office of Orphan Products Development	Giant Cell Arteritis	February 1994	Phase 2
NCT00627666	Asan Medical Center\|National Cancer Institute (NCI)	Leukemia\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Neoplasms	January 2003	Phase 2
NCT03925233	Xijing Hospital	Breast Cancer Organoids	January 2, 2019
NCT00787761	Northside Hospital, Inc.\|Blood and Marrow Transplant Group of Georgia	Myeloproliferative Disorders\|Kidney Cancer\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases	April 2007	Phase 2
NCT00019409	National Institutes of Health Clinical Center (CC)\|National Cancer Institute (NCI)	Leukemia	October 1999	Phase 3
NCT02480946	Modern Biosciences Ltd\|Covance	Arthritis, Rheumatoid	July 2015	Phase 1
NCT00089349	National Cancer Institute (NCI)	Recurrent Childhood Acute Lymphoblastic Leukemia	July 2004	Phase 2
NCT00950989	Amgen	Rheumatoid Arthritis	December 30, 2009	Phase 2
NCT00199004	Johann Wolfgang Goethe University Hospital	Adult Acute Lymphocytic Leukemia	April 2004	Phase 4
NCT03775460	London School of Hygiene and Tropical Medicine\|Dr. Soetomo General Hospital\|The Leprosy Mission Trust, India\|Alert Hospital, Ethiopia\|The Leprosy Mission Bangladesh\|Bombay Leprosy Project, India\|Oswaldo Cruz Foundation\|Leprosy Research Initiative\|The Leprosy Mission Nepal	Erythema Nodosum Leprosum	November 15, 2022	Not Applicable
NCT02837146	Maria Stoenoiu\|Université Catholique de Louvain	Rheumatoid Arthritis	December 2015	Phase 3
NCT00004878	Jonsson Comprehensive Cancer Center	Graft Versus Host Disease\|Leukemia		Phase 2
NCT02663622	OncoImmune, Inc.\|Ohio State University\|University of Michigan Rogel Cancer Center\|Indiana University School of Medicine\|Barbara Ann Karmanos Cancer Institute\|National Cancer Institute (NCI)	Graft Versus Host Disease\|Hematopoietic Stem Cell Transplantation\|Leukemia	September 19, 2016	Phase 2
NCT00513474	Massachusetts General Hospital	Chronic Myeloproliferative Disorders\|Graft Versus Host Disease\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Neoplasms	January 2008	Phase 1
NCT00455286	National Health Research Institutes, Taiwan\|National Taiwan University Hospital\|Mackay Memorial Hospital\|China Medical University Hospital\|National Cheng-Kung University Hospital\|Chi Mei Medical Hospital\|Taichung Veterans General Hospital	Primary Central Nervous System Lymphoma	November 2006	Phase 2
NCT01390402	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Leukemia\|Chronic Myelogenous Leukemia	January 2012	Phase 2
NCT03904680	Cairo University	Psoriasis	April 2019	Phase 4
NCT02373813	Amgen	Rheumatoid Arthritis	February 20, 2015	Phase 3
NCT03728478	Istituto Giannina Gaslini\|Agenzia Italiana del Farmaco\|Compagnia di San Paolo\|Pfizer	Oligoarthritis, Juvenile\|Polyarthritis, Juvenile, Rheumatoid Factor Negative	May 29, 2019	Phase 3
NCT00199186	Johann Wolfgang Goethe University Hospital	Philadelphia Positive Acute Lymphoblastic Leukemia\|Lymphoid Blastic Phase of Chronic Myeloid Leukemia	March 2002	Phase 2
NCT01793259	medac GmbH	Rheumatoid Arthritis	July 2012	Phase 3
NCT02576067	Icahn School of Medicine at Mount Sinai\|Brigham and Women´s Hospital\|Massachusetts General Hospital\|Unity Health Toronto\|National Institutes of Health (NIH)\|National Heart, Lung, and Blood Institute (NHLBI)	Vascular Inflammation\|Atherosclerotic Cardiovascular Disease	December 18, 2015	Phase 3
NCT02611037	H. Lee Moffitt Cancer Center and Research Institute	Malignant Pleural Mesothelioma\|Mesothelioma	March 4, 2016	Phase 2
NCT00004162	University of Alabama at Birmingham\|National Cancer Institute (NCI)	Lymphoma	June 1997	Phase 1
NCT03970096	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Acute Biphenotypic Leukemia\|Acute Leukemia of Ambiguous Lineage\|Acute Lymphoblastic Leukemia\|Acute Myeloid Leukemia\|Acute Undifferentiated Leukemia\|Blastic Plasmacytoid Dendritic Cell Neoplasm\|Lymphoblastic Lymphoma\|Mixed Phenotype Acute Leukemia\|Acute Leukemia\|Hematopoietic and Lymphoid Cell Neoplasm	November 19, 2019	Phase 2
NCT00002532	Hannover Medical School\|National Cancer Institute (NCI)	Leukemia	January 1993	Phase 2
NCT02313922	Zhejiang University\|Shanghai CP Guojian Pharmaceutical Co., Ltd.	Psoriasis	November 2014	Phase 4
NCT02481310	Northwestern University\|National Cancer Institute (NCI)\|Millennium Pharmaceuticals, Inc.	Adult Burkitt Lymphoma\|B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between Diffuse Large B-Cell Lymphoma and Burkitt Lymphoma\|Diffuse Large B-Cell Lymphoma\|MYC Gene Mutation\|Plasmablastic Lymphoma	October 28, 2015	Phase 1\|Phase 2
NCT00645632	Mayo Clinic\|National Cancer Institute (NCI)	Sarcoma	November 1990	Not Applicable
NCT00385788	M.D. Anderson Cancer Center	Hodgkin´s Disease	July 2005	Phase 2
NCT00005641	H. Lee Moffitt Cancer Center and Research Institute\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Graft Versus Host Disease\|Leukemia\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes	September 1997	Phase 2
NCT00679731	AbbVie (prior sponsor, Abbott)\|AbbVie	Psoriasis	April 2008	Phase 3
NCT00673179	M.D. Anderson Cancer Center	Osteosarcoma	May 2008	Not Applicable
NCT01651936	Merck Sharp & Dohme LLC	Rheumatoid Arthritis	August 29, 2012	Phase 2
NCT00002865	Wake Forest University Health Sciences\|National Cancer Institute (NCI)	Leukemia	April 1995	Phase 2
NCT02374021	Brigham and Women´s Hospital\|Columbia University	Arthritis, Rheumatoid	July 2016	Phase 4
NCT00199056	Johann Wolfgang Goethe University Hospital	Adult Acute Lymphocytic Leukemia	October 1999	Phase 4
NCT00251641	Merck Sharp & Dohme LLC	Psoriasis	September 1, 2005	Phase 3
NCT04483466	George Washington University	Investigate the Effect(s) of Methotrexate Treatment on Arthritis Disease Severity	December 1, 2022	Phase 3
NCT01760226	Baylor College of Medicine\|National Cancer Institute (NCI)	Diffuse Large B Cell Lymphoma\|Post Transplant Lymphoproliferative Disorder\|Primary Mediastinal (Thymic) Large B-cell Lymphoma	January 2013	Early Phase 1
NCT01875237	M.D. Anderson Cancer Center\|Bellicum Pharmaceuticals	Leukemia\|Myeloma\|Myeloproliferative Diseases	December 27, 2013	Phase 1\|Phase 2
NCT00303810	Universitätsklinikum Hamburg-Eppendorf	Brain and Central Nervous System Tumors	January 2001	Not Applicable
NCT01964755	University of Miami	Epstein Barr Virus Associated Non Hodgkin´s Lymphoma\|Epstein Barr Virus Associated Hodgkin´s Lymphoma\|Post-Transplant Lymphoproliferative Disease	April 21, 2009	Phase 2
NCT00667342	St. Jude Children´s Research Hospital\|Genentech, Inc.	Osteosarcoma\|Malignant Fibrous Histiocytoma (MFH) of Bone	June 3, 2008	Phase 2
NCT02644499	Jawaharlal Institute of Postgraduate Medical Education & Research	Rheumatoid Arthritis	December 31, 2015	Phase 4
NCT01116141	Chelsea Therapeutics	Rheumatoid Arthritis	September 2010	Phase 2
NCT03383406	Asan Medical Center	Diffuse Large B Cell Lymphoma	December 1, 2016	Phase 2
NCT03589833	Peking Union Medical College Hospital	Arthritis, Rheumatoid	May 14, 2019	Phase 4
NCT04120350	Peking Union Medical College Hospital\|Beijing Tiantan Hospital\|Xuanwu Hospital, Beijing\|Peking University Third Hospital\|Beijing Hospital\|Peking University First Hospital\|Chinese PLA General Hospital	Primary Central Nervous System Lymphoma	August 16, 2019	Phase 1\|Phase 2
NCT03286634	National Hospital Organization Nagoya Medical Center	Down Syndrome\|Acute Lymphoblastic Leukemia\|Childhood Cancer	April 18, 2017	Phase 2
NCT00754572	Hoffmann-La Roche	Rheumatoid Arthritis	February 2009	Phase 3
NCT01528163	Cliniques universitaires Saint-Luc- Université Catholique de Louvain	Squamous Cell Carcinoma of the Head and Neck	February 2012	Phase 2
NCT04628767	National Cancer Institute (NCI)	Renal Pelvis and Ureter Urothelial Carcinoma	May 6, 2021	Phase 3
NCT00003640	European Organisation for Research and Treatment of Cancer - EORTC	Bladder Cancer	September 1998	Phase 2
NCT00767325	Bristol-Myers Squibb	Rheumatoid Arthritis	December 2008	Phase 3
NCT03710772	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Mantle Cell Lymphoma	May 1, 2019	Phase 2
NCT05594680	Tanta University	Rheumatoid Arthritis	November 1, 2022	Phase 3
NCT03219437	AbbVie	Psoriasis	July 30, 2018	Phase 3
NCT04562558	xiang yang\|Peking Union Medical College Hospital	Gestational Trophoblastic Tumor\|Gestational Trophoblastic Neoplasia\|Stage I Gestational Trophoblastic Tumor\|Stage II Gestational Trophoblastic Tumor\|Stage III Gestational Trophoblastic Tumor\|Invasive Mole\|Choriocarcinoma	September 29, 2020	Not Applicable
NCT00002792	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Leukemia\|Myelodysplastic+Myeloproliferative Diseases	June 1996	Phase 2
NCT02309359	Ablynx	Rheumatoid Arthritis	January 2015	Phase 2
NCT00036153	Astellas Pharma Inc\|Astellas Pharma US, Inc.	Rheumatoid Arthritis	March 2002	Phase 3
NCT00054340	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Graft Versus Host Disease\|Leukemia\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases	October 2002	Phase 1\|Phase 2
NCT00058461	National Cancer Institute (NCI)	B-cell Childhood Acute Lymphoblastic Leukemia\|Childhood Burkitt Lymphoma\|Childhood Diffuse Large Cell Lymphoma\|Childhood Immunoblastic Large Cell Lymphoma\|L3 Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood Large Cell Lymphoma\|Recurrent Childhood Lymphoblastic Lymphoma\|Recurrent Childhood Small Noncleaved Cell Lymphoma	November 2003	Phase 2
NCT01773395	Dana-Farber Cancer Institute\|Massachusetts General Hospital\|Beth Israel Deaconess Medical Center	Myelodysplastic Syndrome\|Acute Myeloid Leukemia\|Chronic Myelomonocytic Leukemia	January 8, 2013	Phase 2
NCT02690922	Tongji Hospital	ph&addition; Acute Lymphoblastic Leukemia	March 2016	Phase 4
NCT02129582	Case Comprehensive Cancer Center	Acute Myeloid Leukemia\|Hematologic Malignancies\|Acute Lymphocytic Leukemia\|Non Hodgkin Lymphoma\|Hodgkin Lymphoma\|Multiple Myeloma\|Myelodysplastic Syndrome\|Chronic Lymphocytic Leukemia\|Chronic Myeloid Leukemia\|Myelofibrosis\|Myeloproliferative Syndrome	November 5, 2014	Phase 1
NCT01438021	City of Hope Medical Center\|National Cancer Institute (NCI)	Leptomeningeal Metastases	September 2012	Not Applicable
NCT02115204	West German Study Group\|AGO Germany	Breast Cancer	June 2000	Phase 3
NCT02143414	National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|B Acute Lymphoblastic Leukemia\|B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1\|Recurrent Acute Lymphoblastic Leukemia\|Refractory Acute Lymphoblastic Leukemia	January 12, 2015	Phase 2
NCT02688140	Technische Universität Dresden\|Gruppo Italiano Malattie EMatologiche dell´Adulto\|Groupe Francophone des Myelodysplasies\|HOVON - Dutch Haemato-Oncology Association\|Programa para el Tratamiento de Hemopatías Malignas\|German Federal Ministry of Education and Research\|Teva Pharmaceuticals Europe	Acute Promyelocytic Leukemia	June 2016	Phase 3
NCT00025545	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Leukemia	March 1996	Phase 2
NCT02845882	Children´s Cancer Group, China\|Shanghai Children´s Medical Center\|Tongji Hospital\|West China Second University Hospital\|Qilu Hospital of Shandong University\|Tianjin Medical University Cancer Institute and Hospital\|Children´s Hospital Of Soochow University\|Nanjing Children´s Hospital\|Xiangya Hospital of Central South University	Lymphoblastic Lymphoma	January 2016	Phase 3
NCT01164579	Pfizer	Rheumatoid Arthritis	October 2010	Phase 2
NCT00004231	Northwestern University\|National Cancer Institute (NCI)	Lymphoma	October 1999	Phase 2
NCT01679951	Janssen Research & Development, LLC	Rheumatoid Arthritis	October 31, 2012	Phase 2
NCT04314193	Erasmus Medical Center\|St. Antonius Hospital\|Longfonds	Sarcoidosis, Pulmonary	June 1, 2020	Phase 4
NCT00476190	Dana-Farber Cancer Institute\|Massachusetts General Hospital\|Boston Children´s Hospital\|NCIC Clinical Trials Group	Acute Lymphoblastic Leukemia	April 2007	Phase 2
NCT00027573	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Kidney Cancer	October 2001	Phase 2
NCT00301925	Institute of Cancer Research, United Kingdom	Breast Cancer	December 16, 2005	Phase 3
NCT01168219	National Cancer Institute (NCI)	Acute Myeloid Leukemia\|Adult Acute Megakaryoblastic Leukemia\|Adult Acute Monoblastic Leukemia\|Adult Acute Monocytic Leukemia\|Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11\|Adult Acute Myeloid Leukemia With Maturation\|Adult Acute Myeloid Leukemia With Minimal Differentiation\|Adult Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11\|Adult Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1\|Adult Acute Myeloid Leukemia With t(9;11)(p21.3;q23.3); MLLT3-MLL\|Adult Acute Myeloid Leukemia Without Maturation\|Adult Acute Myelomonocytic Leukemia\|Adult Erythroleukemia\|Adult Pure Erythroid Leukemia\|Alkylating Agent-Related Acute Myeloid Leukemia\|de Novo Myelodysplastic Syndrome\|Myelodysplastic Syndrome\|Myelodysplastic Syndrome With Excess Blasts\|Recurrent Adult Acute Myeloid Leukemia\|Secondary Myelodysplastic Syndrome	July 15, 2010	Phase 2
NCT02837965	CHU de Reims	Bullous Pemphigoid	April 2013
NCT00658047	Chelsea Therapeutics	Arthritis, Rheumatoid	April 2008	Phase 2
NCT00165178	Dana-Farber Cancer Institute\|Boston Children´s Hospital\|University of Rochester\|McMaster University\|San Jorge Children´s Hospital (Puerto Rico)\|St. Justine´s Hospital\|Maine Children´s Cancer Program\|Ochsner Health System\|Tulane University School of Medicine\|Laval University\|Columbia University	Acute Lymphoblastic Leukemia	September 2000	Phase 3
NCT00005866	Southwest Oncology Group\|National Cancer Institute (NCI)	Leukemia\|Myelodysplastic Syndromes	February 2000	Phase 3
NCT00244556	Wyeth is now a wholly owned subsidiary of Pfizer	Rheumatoid Arthritis	March 2003	Phase 4
NCT00424294	Pfizer	Arthritis, Rheumatoid	June 2006	Phase 2
NCT00920608	AstraZeneca	Rheumatoid Arthritis	May 2009	Phase 1
NCT00463008	New Approaches to Brain Tumor Therapy Consortium\|National Cancer Institute (NCI)	Brain and Central Nervous System Tumors	May 2004	Not Applicable
NCT00349674	Hospices Civils de Lyon	Systemic Wegener´s Granulomatosis	January 1999	Phase 3
NCT02724904	Massachusetts General Hospital\|Adienne SA\|Dana-Farber Cancer Institute	Lymphoma	May 2017	Phase 1\|Phase 2
NCT00206219	AstraZeneca	Squamous Cell Carcinoma of the Head and Neck	November 2003	Phase 3
NCT01011920	International Extranodal Lymphoma Study Group (IELSG)	Central Nervous System Lymphoma	November 2009	Phase 2
NCT00468546	Hoffmann-La Roche\|Biogen	Rheumatoid Arthritis	May 2003	Phase 3
NCT00184886	Radboud University Medical Center\|ZonMw: The Netherlands Organisation for Health Research and Development	Methotrexate\|Vasodilation	November 2003	Not Applicable
NCT04043494	University Hospital Muenster\|Deutsche Krebshilfe e.V., Bonn (Germany)	Lymphoblastic Lymphoma, Childhood	August 23, 2019	Phase 3
NCT01855568	CHA University	Ectopic Pregnancy	May 2013	Phase 3
NCT03020030	Dana-Farber Cancer Institute\|Servier	Acute Lymphoblastic Leukemia, Pediatric	March 3, 2017	Phase 3
NCT01185353	Eli Lilly and Company\|Incyte Corporation	Arthritis, Rheumatoid	October 2010	Phase 2
NCT02085655	Huiqiang Huang\|Sun Yat-sen University	Extranodal NK-T-Cell Lymphoma, Nasal and Nasal-Type	April 25, 2013	Phase 3
NCT02779283	OHSU Knight Cancer Institute\|National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|Acute Myeloid Leukemia	January 13, 2016	Phase 1
NCT04609046	National Cancer Institute (NCI)	Central Nervous System Lymphoma\|Diffuse Large B-Cell Lymphoma	January 15, 2021	Phase 1
NCT03689465	Nanfang Hospital of Southern Medical University	Hematopoietic Stem Cell Transplantation	October 29, 2018	Phase 4
NCT00989352	University Hospital Freiburg\|Universitätsklinikum Köln\|Ludwig-Maximilians - University of Munich\|University Hospital Heidelberg\|University Hospital Ulm	Primary Non Hodgkin Lymphoma of the Central Nervous System	September 2009	Phase 2
NCT02151851	UCB Pharma SA, Belgium\|Parexel\|UCB Pharma	Rheumatoid Arthritis	July 2014	Phase 3
NCT03349281	Julio Barredo, MD\|Takeda\|University of Miami	Refractory Acute Lymphoblastic Leukemia\|Relapsed Acute Lymphoblastic Leukemia	March 25, 2019	Phase 1
NCT00654368	Amgen\|Wyeth is now a wholly owned subsidiary of Pfizer	Rheumatoid Arthritis	June 2008	Phase 4
NCT00002542	NCIC Clinical Trials Group\|Canadian Cancer Trials Group	Breast Cancer	July 20, 1993	Phase 3
NCT02303821	Amgen\|Therapeutic Advances in Childhood Leukemia & Lymphoma (TACL) - Study Design & Execution Collaborator\|Innovative Therapies For Children with Cancer Consortium	Acute Lymphoblastic Leukemia (ALL)	February 16, 2015	Phase 1
NCT00005802	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Leukemia	June 1999	Phase 1\|Phase 2
NCT02723994	Incyte Corporation\|Children´s Oncology Group	Leukemia	September 30, 2016	Phase 2
NCT02660684	Astellas Pharma Korea, Inc.\|Astellas Pharma Inc	Graft Versus Host Disease	February 2008	Phase 4
NCT01010581	4SC AG	Rheumatoid Arthritis	November 2009	Phase 2
NCT00061945	National Cancer Institute (NCI)	Acute Undifferentiated Leukemia\|B-cell Adult Acute Lymphoblastic Leukemia\|B-cell Childhood Acute Lymphoblastic Leukemia\|L1 Adult Acute Lymphoblastic Leukemia\|L1 Childhood Acute Lymphoblastic Leukemia\|L2 Adult Acute Lymphoblastic Leukemia\|L2 Childhood Acute Lymphoblastic Leukemia\|Philadelphia Chromosome Negative Adult Precursor Acute Lymphoblastic Leukemia\|Philadelphia Chromosome Positive Adult Precursor Acute Lymphoblastic Leukemia\|Philadelphia Chromosome Positive Childhood Precursor Acute Lymphoblastic Leukemia\|T-cell Adult Acute Lymphoblastic Leukemia\|T-cell Childhood Acute Lymphoblastic Leukemia\|Untreated Adult Acute Lymphoblastic Leukemia\|Untreated Childhood Acute Lymphoblastic Leukemia	June 2003	Phase 1\|Phase 2
NCT00278278	Gesellschaft fur Padiatrische Onkologie und Hamatologie - Germany\|National Cancer Institute (NCI)	Brain and Central Nervous System Tumors	September 2003	Phase 3
NCT04131231	Peking Union Medical College	Lung Cancer\|Breast Cancer\|Malignant Pleural Effusion	October 15, 2019	Not Applicable
NCT00075725	Children´s Oncology Group\|National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|Adult B Acute Lymphoblastic Leukemia\|Childhood B Acute Lymphoblastic Leukemia	December 29, 2003	Phase 3
NCT01156883	Gruppo Italiano Malattie EMatologiche dell´Adulto	Leukemia	April 2010	Not Applicable
NCT02079948	University of Florida\|National Institute on Aging (NIA)	Inflammation\|Aging	February 2014	Phase 2
NCT04481815	Second Affiliated Hospital, School of Medicine, Zhejiang University	PCNSL	October 1, 2020	Phase 2
NCT01187264	Postgraduate Institute of Medical Education and Research	Psoriasis	August 2008	Phase 4
NCT02427620	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Blastoid Variant Mantle Cell Lymphoma\|Mantle Cell Lymphoma\|Pleomorphic Variant Mantle Cell Lymphoma	June 3, 2015	Phase 2
NCT05135858	Assistance Publique - Hôpitaux de Paris\|BTG International Inc.	Primary Central Nervous System Lymphoma	September 15, 2022	Phase 1
NCT02273583	Grupo de Apoio ao Adolescente e a Crianca com Cancer	High Grade Osteosarcoma	May 2006	Phase 2
NCT00005596	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia	April 2000	Phase 3
NCT02315326	Memorial Sloan Kettering Cancer Center\|Pharmacyclics LLC.\|Janssen Biotech, Inc.	Adult Patients With Newly Diagnosed or Relapsed or Refractory Primary Central Nervous System Lymphoma (PCNSL)\|Or Relapsed or Refractory Secondary Central Nervous System Lymphoma (SCNSL)	December 2014	Phase 1\|Phase 2
NCT03371667	Assistance Publique - Hôpitaux de Paris	Allogeneic Disease\|GVH - Graft Versus Host Reaction\|GVHD, Acute\|Stem Cell Transplant Complications	August 16, 2018	Phase 3
NCT02828358	National Cancer Institute (NCI)	Acute Leukemia of Ambiguous Lineage\|B Acute Lymphoblastic Leukemia\|Mixed Phenotype Acute Leukemia	March 27, 2017	Phase 2
NCT01256398	National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1	December 14, 2010	Phase 2
NCT00003056	Baxalta now part of Shire\|Takeda	Leukemia\|Lymphoma\|Graft Versus Host Disease	April 1, 1997	Phase 3
NCT00098839	Children´s Oncology Group\|National Cancer Institute (NCI)	Recurrent Childhood Acute Lymphoblastic Leukemia	February 2005	Phase 1\|Phase 2
NCT00506922	M.D. Anderson Cancer Center\|Astex Pharmaceuticals, Inc.	Leukemia\|Lymphoma	September 2000	Phase 1\|Phase 2
NCT00106548	Hoffmann-La Roche	Rheumatoid Arthritis		Phase 3
NCT00952016	Royal Marsden NHS Foundation Trust	Advanced Colorectal Cancer	February 2009	Phase 2
NCT05208034	Nishtar Medical University	Ectopic Pregnancy	January 1, 2020	Not Applicable
NCT05026229	First Affiliated Hospital Xi´an Jiaotong University	Precursor Cell Lymphoblastic Leukemia-Lymphoma\|Philadelphia-Positive Acute Lymphoblastic Leukemia\|ALL, Adult	September 6, 2021	Not Applicable
NCT01754805	Astellas Pharma Inc	Rheumatoid Arthritis	January 22, 2010	Phase 1
NCT01308255	University of Leeds	Rheumatoid Arthritis	September 2006	Phase 4
NCT03808610	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Recurrent B Acute Lymphoblastic Leukemia\|Recurrent T Acute Lymphoblastic Leukemia\|Refractory B Acute Lymphoblastic Leukemia\|Refractory T Acute Lymphoblastic Leukemia	April 3, 2019	Phase 1\|Phase 2
NCT03699631	Medical College of Wisconsin	Hematologic Malignancy	November 6, 2018	Phase 2
NCT01172639	P. Verschueren\|Agentschap voor Innovatie door Wetenschap en Technologie\|Universitaire Ziekenhuizen KU Leuven	Rheumatoid Arthritis	February 2009	Phase 4
NCT03028467	GlaxoSmithKline	Arthritis, Rheumatoid	January 24, 2017	Phase 1\|Phase 2
NCT00928018	Dana-Farber Cancer Institute\|Brigham and Women´s Hospital\|Massachusetts General Hospital\|National Cancer Institute (NCI)	Non-hodgkin Lymphoma\|Hodgkin Lymphoma	June 2009	Phase 3
NCT02057250	Sanofi\|Regeneron Pharmaceuticals	RA	March 2014	Phase 3
NCT05519579	Northside Hospital, Inc.	Acute Lymphoblastic Leukemia	November 1, 2022	Phase 2
NCT00669812	Cancer Research UK\|National Cancer Institute (NCI)	Lymphoma\|Small Intestine Cancer	February 2008	Phase 2
NCT04169828	University of British Columbia\|The Arthritis Society, Canada\|University of Calgary\|IWK Health Centre\|The Hospital for Sick Children\|McGill University Health Centre+Research Institute of the McGill University Health Centre\|London Health Sciences Centre\|University of Manitoba\|Children´s Hospital of Eastern Ontario\|Alberta Children´s Hospital\|McMaster University\|McMaster Children´s Hospital\|Université de Montréal\|Royal University Hospital Foundation\|Memorial University of Newfoundland	Juvenile Idiopathic Arthritis	August 2, 2019	Not Applicable
NCT00513188	University of Miami	Lymphoma	February 2007	Not Applicable
NCT00074438	Genentech, Inc.\|Roche Pharma AG	Rheumatoid Arthritis	June 2003	Phase 2
NCT00281905	Children´s Cancer and Leukaemia Group\|National Cancer Institute (NCI)	Brain and Central Nervous System Tumors\|Neuroblastoma	June 1992	Phase 2
NCT02105636	Bristol-Myers Squibb\|Ono Pharmaceutical Co. Ltd	Squamous Cell Carcinoma of the Head and Neck	May 29, 2014	Phase 3
NCT00720629	H. Lee Moffitt Cancer Center and Research Institute\|National Institutes of Health (NIH)\|National Cancer Institute (NCI)	Graft Versus Host Disease	December 2007	Phase 2
NCT00847886	Lexicon Pharmaceuticals	Rheumatoid Arthritis	February 2009	Phase 1
NCT01410695	AB Science	Rheumatoid Arthritis (RA)	July 2011	Phase 2\|Phase 3
NCT00004748	National Center for Research Resources (NCRR)\|Tufts Medical Center\|Office of Rare Diseases (ORD)	Liver Cirrhosis, Biliary	November 1989	Phase 3
NCT03959241	Medical College of Wisconsin\|National Heart, Lung, and Blood Institute (NHLBI)\|Blood and Marrow Transplant Clinical Trials Network\|National Cancer Institute (NCI)\|National Marrow Donor Program	Acute Leukemia\|Chronic Myelogenous Leukemia (CML)\|Myelodysplasia\|Lymphoma	June 25, 2019	Phase 3
NCT00048568	Bristol-Myers Squibb	Rheumatoid Arthritis	December 2002	Phase 3
NCT00002476	Cancer Research UK\|National Cancer Institute (NCI)	Head and Neck Cancer	January 1990	Phase 3
NCT00424502	Hoffmann-La Roche	Rheumatoid Arthritis	January 2007	Phase 4
NCT00537550	Gruppo Italiano Malattie EMatologiche dell´Adulto	Leukemia, Lymphocytic, Acute	July 2000	Not Applicable
NCT01951885	Case Comprehensive Cancer Center	Chronic Myelogenous Leukemia\|Acute Lymphoblastic Leukemia\|Acute Myeloid Leukemia\|Acute Biphenotypic Leukemia\|Myelodysplastic Syndrome\|Myeloproliferative Neoplasm\|Non-Hodgkin Lymphoma\|Hodgkins Disease\|Chronic Lymphocytic Leukemia\|Multiple Myeloma	July 7, 2014	Phase 3
NCT00003728	European Organisation for Research and Treatment of Cancer - EORTC\|National Cancer Institute (NCI)	Leukemia\|Lymphoma	December 1998	Phase 3
NCT00000395	University of Alabama at Birmingham\|National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)\|Office of Dietary Supplements (ODS)	Rheumatoid Arthritis\|Adjuvant Arthritis	September 1996	Phase 2
NCT01251614	AbbVie (prior sponsor, Abbott)\|AbbVie	Plaque Psoriasis	December 2010	Phase 3
NCT01181271	Massachusetts General Hospital\|Dana-Farber Cancer Institute	Diffuse, Large B-Cell, Lymphoma\|Lymphoma, Low-Grade\|T-Cell Lymphoma\|Mantle-Cell Lymphoma\|Hodgkin´s Lymphoma\|Chronic Lymphocytic Leukemia\|Lymphoma, Small Lymphocytic	August 2010	Phase 2
NCT04872790	OHSU Knight Cancer Institute\|AbbVie\|Oregon Health and Science University	B Acute Lymphoblastic Leukemia\|B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1\|Recurrent B Acute Lymphoblastic Leukemia	October 2, 2022	Phase 1
NCT00276757	Histiocyte Society\|National Cancer Institute (NCI)	Childhood Langerhans Cell Histiocytosis	April 2001	Not Applicable
NCT02248792	Narayana Medical College & Hospital	Severe Plaque Type Psoriasis	November 2013	Phase 4
NCT01245452	Patrick Durez\|Université Catholique de Louvain	Rheumatoid Arthritis	May 2010	Not Applicable
NCT00262925	National Cancer Institute (NCI)	Recurrent Adult Acute Lymphoblastic Leukemia	June 2006	Phase 2
NCT00233558	Abbott	Rheumatoid Arthritis	June 2005	Phase 4
NCT00348413	Singapore National Eye Centre\|International Stem Cell Forum	Graves Ophthalmopathy	June 2003	Not Applicable
NCT03121014	University of Illinois at Chicago	Acute Myeloid Leukemia\|Myelodysplastic Syndromes	April 24, 2017	Phase 2
NCT00003776	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)	Sarcoma	December 1998	Phase 2
NCT03520842	Stanford University	KRAS Gene Mutation\|Metastatic Malignant Neoplasm in the Brain\|Recurrent Non-Small Cell Lung Carcinoma\|Stage IV Non-Small Cell Lung Cancer AJCC v7	August 14, 2018	Phase 2
NCT01612247	University of Vermont\|Maimonides Medical Center\|Dartmouth-Hitchcock Medical Center	Breast Cancer	February 2011	Not Applicable
NCT00882206	Masonic Cancer Center, University of Minnesota	Leukemia\|Lymphoma	April 2009	Phase 2
NCT00027547	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Leukemia	July 2001	Phase 1\|Phase 2
NCT01614197	Therapeutic Advances in Childhood Leukemia Consortium\|Pfizer	Lymphoblastic Leukemia, Acute, Childhood\|Lymphoblastic Lymphoma\|Peripheral T-cell Lymphoma	March 2015	Phase 1
NCT01163747	Genentech, Inc.	Rheumatoid Arthritis	September 2010	Phase 4
NCT01399697	Hoffmann-La Roche	Rheumatoid Arthritis	September 2011	Phase 4
NCT00656591	Institute of Child Health	Child Mortality	March 2005
NCT02208037	National Heart, Lung, and Blood Institute (NHLBI)\|Blood and Marrow Transplant Clinical Trials Network\|National Cancer Institute (NCI)	Acute Leukemia\|Chronic Myelogenous Leukemia\|Myelodysplasia\|Chronic Lymphocytic Leukemia\|Small Lymphocytic Lymphoma\|Lymphoma, B-Cell\|Lymphoma, Follicular\|Lymphoma, Large B-Cell, Diffuse\|Hodgkin´s Lymphoma	August 2014	Phase 2
NCT03384654	Janssen Research & Development, LLC	Precursor Cell Lymphoblastic Leukemia-Lymphoma	May 14, 2018	Phase 2
NCT04752163	M.D. Anderson Cancer Center	Hematopoietic and Lymphoid Cell Neoplasm\|Recurrent Acute Lymphoblastic Leukemia\|Recurrent Acute Myeloid Leukemia\|Recurrent Chronic Myelomonocytic Leukemia\|Recurrent Myelodysplastic Syndrome\|Refractory Acute Lymphoblastic Leukemia\|Refractory Acute Myeloid Leukemia\|Refractory Chronic Myelomonocytic Leukemia\|Refractory Myelodysplastic Syndrome	March 25, 2021	Phase 1\|Phase 2
NCT00612274	Yale University	Stem Cell Transplantation	October 2007	Early Phase 1
NCT01800162	University of Pennsylvania	Persistent Pregnancy of Unknown Location\|Ectopic Pregnancy	February 2013	Phase 1\|Phase 2
NCT00002580	Scottish Cancer Therapy Network\|National Cancer Institute (NCI)	Breast Cancer	June 1993	Phase 3
NCT01746680	Chong Kun Dang Pharmaceutical	Rheumatoid Arthritis	August 2012	Phase 4
NCT00189488	Swedish Orphan Biovitrum\|Amgen	Graft Versus Host Disease\|Hematologic Malignancies	December 2005	Phase 2
NCT01312818	Masonic Cancer Center, University of Minnesota\|Millennium Pharmaceuticals, Inc.	Acute Lymphoblastic Leukemia	June 2011	Phase 2
NCT00647049	University Hospital Freiburg\|University Hospital Tuebingen	Primary Non Hodgkin Lymphoma of the Central Nervous System	January 2007	Phase 2
NCT02097173	medac GmbH\|PPD	Psoriasis	May 2013	Phase 1
NCT00808210	Genentech, Inc.	Rheumatoid Arthritis	March 5, 2009	Phase 2
NCT00298012	Rheumatism Foundation Hospital\|Orion Corporation, Orion Pharma	Spondylarthropathies\|Spondylitis, Ankylosing	March 2006	Phase 4
NCT02312219	Massachusetts General Hospital\|Brigham and Women´s Hospital\|Harvard School of Public Health (HSPH)\|University of California, San Francisco	HIV\|Inflammation\|Atherosclerosis	November 2014
NCT01942174	University Hospital, Montpellier\|Hôpital Cochin\|Pfizer	Rheumatoid Arthritis	September 27, 2013	Phase 3
NCT03254589	Flinders University\|University of South Australia\|medac GmbH	Rheumatoid Arthritis\|Stiffness, Aortic\|Endothelial Dysfunction\|Cardiovascular Risk Factor	October 1, 2017	Phase 4
NCT02934204	Guangdong Provincial People´s Hospital	Primary CNS Lymphoma	February 2016	Phase 2
NCT01004432	Janssen Biotech, Inc.\|Merck Sharp & Dohme LLC	Arthritis\|Arthritis, Rheumatoid\|Autoimmune Diseases	December 2009	Phase 3
NCT03842696	University of Michigan Rogel Cancer Center\|National Institutes of Health (NIH)	Hematologic Diseases\|Acute Leukemia in Remission\|Chronic Myelogenous Leukemia - Chronic Phase\|Chronic Myelogenous Leukemia, Accelerated Phase\|Chronic Myelogenous Leukemia, Blastic Phase\|Myelodysplastic Syndromes\|Mantle Cell Lymphoma\|Follicular Lymphoma\|Diffuse Large B Cell Lymphoma\|Non Hodgkin Lymphoma\|Graft Vs Host Disease\|Graft-versus-host-disease	February 4, 2020	Phase 1\|Phase 2
NCT05457556	Children´s Oncology Group	Acute Lymphoblastic Leukemia\|Acute Myeloid Leukemia\|Myelodysplastic Syndrome	November 23, 2022	Phase 3
NCT01860690	Meir Medical Center	Ectopic Pregnancy	November 2011	Phase 4
NCT00003261	Centro di Riferimento Oncologico - Aviano\|National Cancer Institute (NCI)	Lymphoma	May 1997	Phase 2
NCT00760864	Takeda	Arthritis, Rheumatoid	August 2004	Phase 2
NCT02393859	Amgen	Leukemia, Acute Lymphoblastic	November 10, 2015	Phase 3
NCT02220985	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)\|National Heart, Lung, and Blood Institute (NHLBI)	Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Acute Biphenotypic Leukemia\|Acute Leukemia of Ambiguous Lineage\|Acute Undifferentiated Leukemia\|Allogeneic Hematopoietic Stem Cell Transplant Recipient\|Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Blastic Plasmacytoid Dendritic Cell Neoplasm\|Childhood Acute Lymphoblastic Leukemia in Remission\|Childhood Acute Myeloid Leukemia in Remission\|Donor\|Lymphoblastic Lymphoma\|Myelodysplastic Syndrome With Excess Blasts\|Myelodysplastic Syndrome With Excess Blasts-1\|Myelodysplastic Syndrome With Excess Blasts-2\|Recurrent Acute Lymphoblastic Leukemia\|Recurrent Acute Myeloid Leukemia\|Recurrent Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood Acute Myeloid Leukemia\|Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Refractory Acute Lymphoblastic Leukemia\|Refractory Acute Myeloid Leukemia\|Acute Lymphoblastic Leukemia in Remission\|Acute Myeloid Leukemia in Remission	February 3, 2015	Phase 2
NCT00002524	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Lymphoma	June 1993	Phase 2
NCT00002489	Memorial Sloan Kettering Cancer Center	Extragonadal Germ Cell Tumor\|Ovarian Cancer	October 1991	Phase 2
NCT01404429	Postgraduate Institute of Medical Education and Research	Rheumatoid Arthritis	May 2011	Phase 4
NCT03218059	Shanghai First Maternity and Infant Hospital	Cesarean Scar Pregnancy\|Menstruation	July 15, 2017	Not Applicable
NCT02631239	Ruijin Hospital	Extranodal NK+T-cell Lymphoma, Nasal Type	March 16, 2016	Phase 3
NCT01850680	Sanofi\|Regeneron Pharmaceuticals	Rheumatoid Arthritis	April 2013	Phase 1
NCT00503594	Assistance Publique - Hôpitaux de Paris\|French Innovative Leukemia Organisation	Lymphoma	July 2007	Phase 2
NCT00003702	Gynecologic Oncology Group\|Eastern Cooperative Oncology Group\|National Cancer Institute (NCI)\|GOG Foundation	Good Prognosis Metastatic Gestational Trophoblastic Tumor\|Hydatidiform Mole\|Non-Metastatic Gestational Trophoblastic Tumor\|Uterine Corpus Choriocarcinoma	June 1999	Phase 3
NCT00132899	University of Western Ontario, Canada\|Schering-Plough	Crohn´s Disease	December 2005	Phase 3
NCT00198978	Johann Wolfgang Goethe University Hospital	Adult Acute Lymphocytic Leukemia	January 2003	Phase 4
NCT00109837	Southwest Oncology Group\|National Cancer Institute (NCI)	Leukemia	April 2005	Phase 2
NCT00751517	University of Parma	Wegener´s Granulomatosis\|Churg-Strauss Syndrome\|Microscopic Polyangiitis\|Polyarteritis Nodosa		Phase 2
NCT01175772	HaEmek Medical Center, Israel	Ovarian Carcinoma	August 2010	Phase 2
NCT02280694	HaEmek Medical Center, Israel	Colorectal Cancer	January 2015	Phase 2
NCT00001880	National Heart, Lung, and Blood Institute (NHLBI)\|National Institutes of Health Clinical Center (CC)	Neoplasm Metastasis	March 12, 1999	Phase 2
NCT03066466	Loyola University	Acute Myeloid Leukemia\|Acute Lymphocytic Leukemia\|Myelodysplastic Syndrome	December 10, 2019	Phase 3
NCT02852694	PIBD-Net\|European Commission	Crohn´s Disease	February 28, 2017	Phase 4
NCT02478424	Rabin Medical Center	Graft vs Host Disease	July 2015	Phase 2
NCT00008151	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Leukemia\|Myelodysplastic Syndromes	October 2000	Phase 2
NCT01000610	Hoffmann-La Roche	Rheumatoid Arthritis	March 17, 2008	Phase 4
NCT00301834	University of California, San Francisco\|National Cancer Institute (NCI)	Congenital Amegakaryocytic Thrombocytopenia\|Diamond-blackfan Anemia\|Leukemia\|Myelodysplastic Syndromes\|Severe Congenital Neutropenia	January 2005	Phase 2
NCT04356118	Hui Bu\|Hebei Medical University	Leptomeningeal Metastasis	June 2020	Phase 4
NCT01118013	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Leukemia\|Lymphoma\|Lymphoproliferative Disorder\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Neoplasms	December 2010	Phase 2
NCT00040690	Medical Research Council\|National Cancer Institute (NCI)	Leukemia\|Lymphoma	November 2008	Phase 2
NCT00074269	University of California, San Diego\|National Cancer Institute (NCI)	Breast Cancer	July 2003	Phase 2
NCT00808509	AbbVie (prior sponsor, Abbott)\|Pharma Consulting Group AB\|AbbVie	Arthritis, Rheumatoid	January 2009	Phase 4
NCT00059839	Children´s Oncology Group\|National Cancer Institute (NCI)	Lymphoma	November 2003	Phase 3
NCT00000723	National Institute of Allergy and Infectious Diseases (NIAID)	Lymphoma, Non-Hodgkin\|HIV Infections		Not Applicable
NCT00131027	Japan Adult Leukemia Study Group	Lymphoblastic Leukemia, Acute	September 2002	Phase 3
NCT03440892	Vastra Gotaland Region	Rheumatoid Arthritis	November 1, 2017
NCT01594333	Brigham and Women´s Hospital\|National Heart, Lung, and Blood Institute (NHLBI)	Cardiovascular Disease	April 2013	Phase 3
NCT04530565	National Cancer Institute (NCI)	B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1	October 14, 2020	Phase 3
NCT00720109	National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1\|Childhood B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1	July 14, 2008	Phase 2\|Phase 3
NCT00301860	University of California, San Francisco\|National Cancer Institute (NCI)	Leukemia\|Lymphoma	January 2003	Not Applicable
NCT02329080	International Extranodal Lymphoma Study Group (IELSG)	Diffuse Large B-cell Lymphoma	December 2014	Phase 2
NCT00000703	National Institute of Allergy and Infectious Diseases (NIAID)	Lymphoma, Non-Hodgkin\|HIV Infections		Not Applicable
NCT04677868	Peking University People´s Hospital	Acute GVH Disease	December 23, 2020	Phase 2
NCT00851318	Astellas Pharma Inc\|UCB Japan Co. Ltd.	Rheumatoid Arthritis	March 2009	Phase 3
NCT01187810	South Plains Oncology Consortium	Acute Myelogenous Leukemia\|Acute Lymphoblastic Leukemia\|Non-Hodgkin´s Lymphoma	August 2010	Phase 1
NCT01548001	Jiangsu Simcere Pharmaceutical Co., Ltd.	Rheumatoid Arthritis	May 2012	Phase 4
NCT00006451	Masonic Cancer Center, University of Minnesota	Graft Versus Host Disease\|Leukemia\|Lymphoma	April 1996	Phase 3
NCT03531073	University of Oxford\|National Institute for Health Research, United Kingdom	Psoriatic Arthritis	April 18, 2018
NCT00422942	Hoffmann-La Roche	Rheumatoid Arthritis	January 2006	Phase 2
NCT00621036	University of Texas Southwestern Medical Center	Brain and Central Nervous System Tumors\|Lymphoma\|Lymphoproliferative Disorder\|Small Intestine Cancer	October 19, 2007	Phase 2
NCT00089037	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Graft Versus Host Disease\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases	June 2003	Phase 1\|Phase 2
NCT00189878	Barnsley Hospital	Urticaria	August 2003	Phase 2
NCT00880815	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	CD20 Positive\|Chronic Lymphocytic Leukemia\|Follicular Lymphoma\|Mantle Cell Lymphoma\|Marginal Zone Lymphoma\|Recurrent Diffuse Large B-Cell Lymphoma\|T-Cell Non-Hodgkin Lymphoma	February 17, 2009	Phase 1
NCT00235859	Abbott\|Eisai Limited	Rheumatoid Arthritis	July 2003	Phase 3
NCT02701517	Grupo Español de Linfomas y Transplante Autólogo de Médula Ósea	Unrecognized Condition: Mature B or T-cell Neoplasm	September 2003	Phase 2
NCT00027924	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Leukemia\|Myelodysplastic Syndromes	October 2001	Phase 2
NCT02623426	JHSPH Center for Clinical Trials\|National Eye Institute (NEI)	Uveitis\|Macular Edema	March 9, 2017	Phase 3
NCT04811911	Aswan University Hospital	Psoriasis	December 13, 2020	Phase 4
NCT00041132	Southwest Oncology Group\|National Cancer Institute (NCI)	Lymphoma	September 2002	Phase 2
NCT02433184	University of Leeds	Rheumatoid Arthritis	July 2011	Phase 4
NCT00103285	Children´s Oncology Group\|National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|Childhood B Acute Lymphoblastic Leukemia	April 11, 2005	Phase 3
NCT01403415	National Cancer Institute (NCI)	Childhood B Acute Lymphoblastic Leukemia\|Childhood T Acute Lymphoblastic Leukemia\|Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma\|Recurrent Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood Lymphoblastic Lymphoma	September 2011	Phase 1
NCT03239600	GlaxoSmithKline	Autoimmune Diseases	September 19, 2017	Phase 2
NCT03321890	Sun Yat-sen University	Peripheral T-cell Lymphoma	March 7, 2017	Phase 2
NCT00070174	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia	December 2003	Phase 2
NCT00002805	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia	August 1997	Phase 2
NCT00311636	Gruppo Italiano Mammella (GIM)\|National Cancer Institute (NCI)	Breast Cancer	September 2003	Phase 3
NCT05303727	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University	Neuroblastoma	August 2022	Phase 2
NCT05102448	Shanghai Zhongshan Hospital	Takayasu Arteritis	November 1, 2021	Phase 4
NCT01031030	Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori\|National Cancer Institute (NCI)	Breast Cancer	November 1997	Phase 3
NCT00416819	University of California, San Francisco\|National Cancer Institute (NCI)	Brain and Central Nervous System Tumors\|Lymphoma	September 2003	Not Applicable
NCT01987479	Hoffmann-La Roche	Rheumatoid Arthritis	January 30, 2014	Phase 3
NCT00291915	Goupe d´Etudes et de Recherche Clinique En Rhumatologie	Rheumatoid Arthritis\|Arthritis	May 2004	Phase 4
NCT02684071	Nicklaus Children´s Hospital f+k+a Miami Children´s Hospital	Recurrent Childhood Medulloblastoma\|Recurrent Childhood Ependymoma\|Childhood Atypical Teratoid+Rhabdoid Tumor\|Embryonal Tumor With Abundant Neuropil and True Rosettes\|Metastatic Malignant Neoplasm to the Leptomeninges	February 2016	Phase 2
NCT00589563	City of Hope Medical Center\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Graft Versus Host Disease\|Infection\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Neoplasms\|Precancerous Condition\|Secondary Myelofibrosis\|Small Intestine Cancer	May 2007	Phase 2
NCT01061736	Sanofi\|Regeneron Pharmaceuticals	Rheumatoid Arthritis	March 2010	Phase 2\|Phase 3
NCT02902861	Prof. Kristian Reich\|Sciderm GmbH	Psoriasis Vulgaris	February 2013	Phase 3
NCT01737944	Antares Pharma Inc.	Rheumatoid Arthritis	January 2011	Phase 1\|Phase 2
NCT00814138	University of Kansas Medical Center	Myasthenia Gravis	April 2009	Phase 2
NCT00506155	M.D. Anderson Cancer Center\|Genentech, Inc.	Bladder Cancer	June 2007	Phase 2
NCT01518153	M.D. Anderson Cancer Center	Leukemia\|Lymphoma\|Myeloma\|Myeloproliferative Diseases	February 2012	Phase 2
NCT03007147	Children´s Oncology Group\|National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|B Acute Lymphoblastic Leukemia\|Mixed Phenotype Acute Leukemia\|T Acute Lymphoblastic Leukemia	July 28, 2017	Phase 3
NCT04967950	Peking Union Medical College Hospital	Psoriatic Arthritis	July 15, 2021	Phase 1
NCT01569152	Merck Sharp & Dohme LLC	Rheumatoid Arthritis (RA)	May 22, 2012	Phase 2
NCT01382940	Hoffmann-La Roche	Rheumatoid Arthritis	July 26, 2011	Phase 4
NCT02330380	University Hospitals Cleveland Medical Center\|National Psoriasis Foundation	Psoriasis\|Inflammation	April 2013
NCT05494593	Takeda\|Takeda Development Center Americas, Inc.	Mucopolysaccharidosis (MPS)\|Hunter Syndrome	December 9, 2022	Phase 4
NCT00368654	University of California, Davis\|Genentech, Inc.	Psoriasis	January 2007	Phase 1\|Phase 2
NCT00396747	Université Catholique de Louvain	Rheumatoid Arthritis	June 2003	Phase 4
NCT02416388	University Hospital, Angers	Acute Myeloid Leukemia (AML)	January 2015	Phase 2\|Phase 3
NCT02884635	Astellas Pharma Inc	Rheumatoid Arthritis	September 16, 2016	Phase 2
NCT03206671	University Hospital Muenster\|Deutsche Krebshilfe e.V., Bonn (Germany)	Mature B-cell Non-Hodgkin Lymphoma	August 3, 2017	Phase 3
NCT02305849	Astellas Pharma Inc	Rheumatoid Arthritis	July 25, 2014	Phase 3
NCT00420927	Abbott	Rheumatoid Arthritis	December 2006	Phase 4
NCT03564704	Nanfang Hospital of Southern Medical University	Leukemia\|Leukemia, Acute\|Adult Lymphoblastic Lymphoma\|Leukemia, Lymphoblastic\|Leukemia, T Cell\|Adult Acute Lymphoblastic Leukemia\|Lymphoblastic Lymphoma\|Lymphoblastic Leukemia	February 14, 2016	Phase 2\|Phase 3
NCT00035958	Children´s Hospital Medical Center, Cincinnati\|National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)\|Immunex Corporation	Dermatomyositis	August 2002	Phase 2\|Phase 3
NCT03193931	AIO-Studien-gGmbH	Cancer of Head and Neck	February 2, 2018	Phase 2
NCT01927757	Amgen	Moderate to Severe Rheumatoid Arthritis	May 6, 2013	Phase 4
NCT01790568	University of Michigan Rogel Cancer Center	Graft vs Host Disease\|Hematologic Neoplasms\|Non-Neoplastic Hematologic and Lymphocytic Disorder	December 2014	Phase 2
NCT02251821	Fred Hutchinson Cancer Center\|Incyte Corporation\|National Cancer Institute (NCI)	Primary Myelofibrosis\|Secondary Myelofibrosis	October 20, 2014	Phase 2
NCT00992602	University of Washington\|National Cancer Institute (NCI)	Central Nervous System Metastases\|Leptomeningeal Metastases\|Recurrent Breast Cancer\|Stage IV Breast Cancer\|Tumors Metastatic to Brain	April 2011	Phase 2
NCT01991158	Sun Yat-sen University\|Eli Lilly and Company	Extranodal NK+T-cell Lymphoma, Nasal Type	November 2013	Phase 2
NCT03797872	University of Oxford\|National Institute for Health Research, United Kingdom	Psoriatic Arthritis	April 17, 2019	Phase 4
NCT03117751	St. Jude Children´s Research Hospital\|Incyte Corporation\|Amgen\|Servier	Acute Lymphoblastic Leukemia\|Acute Lymphoblastic Lymphoma	March 29, 2017	Phase 2\|Phase 3
NCT03488225	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia in Remission\|B Acute Lymphoblastic Leukemia\|B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative	March 28, 2018	Phase 2
NCT00002766	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)	Leukemia\|Lymphoma	March 1996	Phase 3
NCT01059773	Janssen-Cilag International NV	Psoriasis	October 2009	Phase 4
NCT02269358	Prof. Arie Levine\|Wolfson Medical Center	Crohn´s Disease	July 2015	Phase 4
NCT00276601	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins\|National Cancer Institute (NCI)	Leukemia	October 2004	Phase 2
NCT02878161	Fen Li\|Central South University	Rheumatoid Arthritis	January 2016	Phase 4
NCT01668680	HaEmek Medical Center, Israel\|Clalit Health Services	Colorectal Cancer Metastatic	September 2012	Phase 2
NCT03719105	New York Medical College\|University of Alabama at Birmingham	NK-Cell Lymphoma\|NK-Cell Leukemia\|Peripheral T Cell Lymphoma	March 1, 2019	Early Phase 1
NCT00513981	Children´s Cancer and Leukaemia Group\|National Cancer Institute (NCI)	Brain and Central Nervous System Tumors\|Sarcoma\|Unspecified Childhood Solid Tumor, Protocol Specific	March 2007	Phase 1
NCT00019864	National Cancer Institute (NCI)	Cardiac Toxicity\|Sarcoma	March 2000	Phase 2
NCT00267865	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	AIDS-Related-Primary Central Nervous System Lymphoma	September 14, 2006	Phase 2
NCT00504777	Hoffmann-La Roche	Rheumatoid Arthritis	July 2007	Phase 4
NCT02693210	Hoffmann-La Roche	Rheumatoid Arthritis	February 2001	Phase 2
NCT02525172	National Taiwan University Hospital	Pompe Disease	August 2015	Phase 4
NCT00259610	University of Alabama at Birmingham\|Amgen\|Barr Laboratories\|Pfizer	Rheumatoid Arthritis	May 2004	Phase 4
NCT01424982	M.D. Anderson Cancer Center	Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Acute Lymphoblastic Leukemia\|Adult Acute Lymphoblastic Leukemia in Complete Remission\|B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1\|Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Philadelphia Chromosome Positive\|Untreated Adult Acute Lymphoblastic Leukemia	October 5, 2011	Phase 2
NCT00281879	OHSU Knight Cancer Institute\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Neoplasms\|Unusual Cancers of Childhood	February 2006	Phase 2
NCT01483690	Therapeutic Advances in Childhood Leukemia Consortium	Acute Lymphoblastic Leukemia\|Precursor B-Cell Lymphoblastic Leukemia\|Precursor T-Cell Lymphoblastic Leukemia	December 2011	Phase 1\|Phase 2
NCT00003783	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia	March 1999	Phase 2
NCT01117441	University Hospital Schleswig-Holstein\|Deutsche Krebshilfe e.V., Bonn (Germany)	Leukemia	June 2010	Phase 3
NCT00003632	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)	Lymphoma	September 1998	Phase 2
NCT00003937	Children´s Oncology Group\|National Cancer Institute (NCI)	Cardiac Toxicity\|Sarcoma	September 1999	Phase 3
NCT00130195	Japan Adult Leukemia Study Group	Acute Lymphoblastic Leukemia	September 2002	Phase 2
NCT04038970	Jiangsu Alphamab Biopharmaceuticals Co., Ltd	Rheumatoid Arthritis	November 8, 2019	Phase 2
NCT02006706	Hoffmann-La Roche	Rheumatoid Arthritis	August 10, 2006	Phase 3
NCT00070135	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Adult Acute Myeloid Leukemia in Remission\|Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome	January 2004	Phase 2
NCT03492658	Leiden University Medical Center	Rheumatoid Arthritis\|Rheumatic Diseases	May 17, 2018	Phase 4
NCT00022126	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia	November 2002	Phase 2
NCT02930343	Jawaharlal Institute of Postgraduate Medical Education & Research	Rheumatoid Arthritis	September 2016	Phase 3
NCT02867800	Monica Bhatia\|Columbia University	Sickle Cell Disease\|Graft Versus Host Disease	July 2016	Phase 1
NCT02420717	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Recurrent B Acute Lymphoblastic Leukemia\|Recurrent Ph-Like Acute Lymphoblastic Leukemia\|Refractory B Acute Lymphoblastic Leukemia\|Refractory Ph-Like Acute Lymphoblastic Leukemia	July 15, 2015	Phase 2
NCT01812954	Jochen Schmitt.\|Merck Sharp & Dohme LLC\|Technische Universität Dresden	Psoriasis	March 2013
NCT00618501	Asan Medical Center\|National Cancer Institute (NCI)	Leukemia	October 2005	Phase 2
NCT02366091	Johns Hopkins University\|National Heart, Lung, and Blood Institute (NHLBI)	Coronary Artery Disease	January 2015	Phase 2
NCT00818961	Northside Hospital, Inc.\|Blood and Marrow Transplant Group of Georgia	Leukemia\|Lymphoma\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases	May 2005	Phase 2
NCT05137262	M.D. Anderson Cancer Center\|AstraZeneca	Urothelial Carcinoma\|Bladder Cancer	October 13, 2021	Phase 2
NCT04239859	Singapore General Hospital\|Translational Immunology Institute	Plaque Psoriasis	January 2022	Phase 4
NCT00045539	New Approaches to Brain Tumor Therapy Consortium\|National Cancer Institute (NCI)	Lymphoma	October 2002	Phase 2
NCT03781375	Amgen	Juvenile Rheumatoid Arthritis	August 24, 2000	Phase 3
NCT00683319	Children´s Cancer and Leukaemia Group\|National Cancer Institute (NCI)	Brain and Central Nervous System Tumors\|Cognitive+Functional Effects\|Long-term Effects Secondary to Cancer Therapy in Children\|Ototoxicity	April 2008
NCT00281983	German CLL Study Group	Chronic Lymphocytic Leukemia	June 2000	Phase 1\|Phase 2
NCT02764515	Chinese SLE Treatment And Research Group\|CHENLIJI Pharmaceutical Company,Guangzhou Pharmaceutical Group\|CHINESE RHEUMATISM DATA CENTER	Rheumatoid Arthritis	September 2015	Phase 4
NCT00502853	Hoffmann-La Roche	Rheumatoid Arthritis	October 25, 2007	Phase 4
NCT00501826	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	T Acute Lymphoblastic Leukemia\|T Lymphoblastic Lymphoma	July 11, 2007	Phase 2
NCT00002755	Scottish Cancer Therapy Network\|National Cancer Institute (NCI)	Breast Cancer	November 1995	Phase 3
NCT01941095	Hoffmann-La Roche	Rheumatoid Arthritis	November 20, 2013	Phase 3
NCT00153530	Charite University, Berlin, Germany\|University Hospital Tuebingen	Central Nervous System Lymphoma	May 2000	Phase 4
NCT03063983	Grupo de Apoio ao Adolescente e a Crianca com Cancer	Osteosarcoma	January 2, 2017	Phase 2
NCT02378298	Göteborg University\|Sahlgrenska University Hospital, Sweden	Ophthalmopathy, Thyroid-Associated	December 2011	Phase 4
NCT00706797	Wyeth is now a wholly owned subsidiary of Pfizer	Rheumatoid Arthritis	September 2008	Phase 4
NCT02799888	Affiliated Hospital to Academy of Military Medical Sciences	Graft-versus-host Disease\|Hematopoietic Stem Cell Transplantation	April 2014	Phase 2
NCT05192889	St. Jude Children´s Research Hospital\|AbbVie	Refractory Acute Lymphoblastic Leukemia\|Relapsed Acute Lymphoblastic Leukemia	August 25, 2022	Phase 1\|Phase 2
NCT04196868	University Hospital, Bordeaux\|Ministry for Health and Solidarity, France	Arthritis, Rheumatoid	December 3, 2020	Phase 2
NCT00866918	Children´s Oncology Group\|National Cancer Institute (NCI)	Childhood Acute Promyelocytic Leukemia With PML-RARA\|Myeloid Neoplasm	March 9, 2009	Phase 3
NCT00002590	Children´s Oncology Group\|National Cancer Institute (NCI)	Lymphoma	July 1994	Phase 2
NCT00293475	OHSU Knight Cancer Institute\|National Cancer Institute (NCI)\|Oregon Health and Science University	Central Nervous System Lymphoma	October 14, 2005	Phase 1\|Phase 2
NCT04588818	Sun Yat-sen University	Uveitis	February 1, 2020	Phase 2
NCT04798755	Hospital San Carlos, Madrid	Uveitis	January 12, 2022	Phase 3
NCT05600426	Boston Children´s Hospital\|Center for International Blood and Marrow Transplant Research\|National Institutes of Health (NIH)\|National Heart, Lung, and Blood Institute (NHLBI)\|North American Pediatric Aplastic Anemia Consortium\|Pediatric Transplantation and Cellular Therapy Consortium\|Blood and Marrow Transplant Clinical Trials Network	Severe Aplastic Anemia	December 2022	Phase 3
NCT01358253	Ruijin Hospital	Acute Lymphoblastic Leukemia	December 2010	Phase 4
NCT05015335	Peking Union Medical College Hospital	Uveitis, Anterior\|Adalimumab	August 19, 2021	Phase 4
NCT01225393	Genentech, Inc.	Rheumatoid Arthritis	November 2010	Phase 2
NCT02206035	William R. Drobyski, MD\|Medical College of Wisconsin	Hematopoietic Stem Cell Transplantation	December 2014	Phase 2
NCT01283971	Hoffmann-La Roche	Rheumatoid Arthritis	May 2011	Phase 4
NCT00727831	University College, London\|Cancer Research UK	Chemotherapeutic Agent Toxicity\|Lymphoma\|Mucositis\|Neurotoxicity	July 2008	Phase 1\|Phase 2
NCT00041288	University of Texas Southwestern Medical Center	Leukemia\|Lymphoma	October 2001	Phase 2
NCT00635726	Hellenic Oncology Research Group\|University Hospital of Crete	Bladder Cancer	February 2008	Phase 2
NCT00993135	Vanderbilt University Medical Center\|National Cancer Institute (NCI)	Leukemia\|Renal Toxicity	December 2008
NCT00006258	Children´s Hospital Los Angeles\|National Cancer Institute (NCI)	Brain and Central Nervous System Tumors	November 1997	Phase 2
NCT01117129	Hoffmann-La Roche	Rheumatoid Arthritis	April 2010	Phase 4
NCT00106535	Hoffmann-La Roche	Rheumatoid Arthritis	January 2005	Phase 3
NCT00290498	M.D. Anderson Cancer Center\|Genentech, Inc.	Lymphoma	August 1, 2005	Phase 2
NCT04247815	Aclaris Therapeutics, Inc.	Rheumatoid Arthritis	March 16, 2020	Phase 2
NCT00199095	Johann Wolfgang Goethe University Hospital	Adult Acute Lymphocytic Leukemia	February 1997	Phase 4
NCT01227408	University of Southern California\|CTI BioPharma	Breast Cancer	February 2009	Phase 2
NCT00450983	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)\|National Institute of Allergy and Infectious Diseases (NIAID)	Graft Versus Host Disease\|Leukemia\|Myelodysplastic Syndromes	December 2006	Phase 2
NCT00002790	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Graft Versus Host Disease\|Leukemia\|Myelodysplastic Syndromes	March 1996	Phase 1\|Phase 2
NCT00587873	Memorial Sloan Kettering Cancer Center	Hodgkin´s Disease	March 1994	Phase 2
NCT00006747	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Graft Versus Host Disease\|Lymphoma	November 2000	Phase 2
NCT02981628	Children´s Oncology Group\|National Cancer Institute (NCI)	Recurrent B Acute Lymphoblastic Leukemia\|Recurrent B Lymphoblastic Lymphoma\|Refractory B Acute Lymphoblastic Leukemia\|Refractory B Lymphoblastic Lymphoma	June 5, 2017	Phase 2
NCT01014767	Tufts Medical Center	Brain Cancer\|Choroid Plexus Tumors	November 2009	Phase 3
NCT02814175	AbbVie	Psoriatic Arthritis	August 5, 2016	Phase 4
NCT00039130	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Leukemia\|Lymphoma	May 2002	Phase 2
NCT00003423	United Kingdom Children´s Cancer Study Group\|National Cancer Institute (NCI)	Lymphoma	May 1995	Phase 3
NCT01754389	Dana-Farber Cancer Institute	Graft Versus Host Disease	January 2013	Phase 2
NCT00002961	Children´s Hospital of Philadelphia	Leukemia	October 1995	Phase 3
NCT01469013	Eli Lilly and Company	Arthritis, Rheumatoid	November 2011	Phase 2
NCT00083031	Dana-Farber Cancer Institute\|National Cancer Institute (NCI)\|Genentech, Inc.	Breast Cancer	July 2003	Phase 2
NCT01862224	Janssen Research & Development, LLC	Rheumatoid Arthritis	July 2013	Phase 2
NCT05303792	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	B Acute Lymphoblastic Leukemia\|B Lymphoblastic Lymphoma	February 2023	Phase 2
NCT02376790	Amgen	Psoriatic Arthritis	March 3, 2015	Phase 3
NCT01162551	Children´s Hospital of Philadelphia\|The Leukemia and Lymphoma Society	Cancer\|Leukemia\|Lymphoma	May 2010	Phase 2
NCT00002487	Ottawa Regional Cancer Centre\|National Cancer Institute (NCI)	Ovarian Cancer	July 1991	Phase 2
NCT00390793	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|BCR-ABL1 Fusion Protein Expression\|Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Philadelphia Chromosome Positive\|Recurrent Acute Lymphoblastic Leukemia\|t(9;22)	September 28, 2006	Phase 2
NCT02293109	Mehrdad Abedi, MD\|Amgen\|University of California, Davis	Contiguous Stage II Adult Lymphoblastic Lymphoma\|Noncontiguous Stage II Adult Lymphoblastic Lymphoma\|Stage I Adult Lymphoblastic Lymphoma\|Stage III Adult Lymphoblastic Lymphoma\|Stage IV Adult Lymphoblastic Lymphoma\|Untreated Adult Acute Lymphoblastic Leukemia	December 17, 2015	Phase 1
NCT00669877	M.D. Anderson Cancer Center	Burkitt´s Lymphoma\|Burkitt´S-like Lymphoma	August 2002	Phase 2
NCT01020734	Asan Medical Center	Leukemia	May 2011	Phase 2
NCT04314219	King Faisal Specialist Hospital & Research Center	Acute Lymphoblastic Leukemia (ALL) in Partial Remission\|Acute Lymphoblastic Leukemia (ALL) in Complete Remission\|Acute Myeloid Leukemia (AML) in Remission	August 15, 2021	Phase 3
NCT02766465	Medical College of Wisconsin\|National Heart, Lung, and Blood Institute (NHLBI)\|Blood and Marrow Transplant Clinical Trials Network\|Dana-Farber Cancer Institute\|National Marrow Donor Program\|Emory University	Sickle Cell Disease	November 2016	Phase 2
NCT00783536	Wyeth is now a wholly owned subsidiary of Pfizer	Rheumatoid Arthritis	November 2008	Phase 4
NCT00357084	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Cancer	May 2006	Phase 2
NCT00003217	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia\|Lymphoma	March 1998	Phase 1
NCT02608112	Hoffmann-La Roche	Rheumatoid Arthritis	December 31, 2015
NCT01186328	Therapeutic Advances in Childhood Leukemia Consortium\|Enzon Pharmaceuticals, Inc.	Lymphoblastic Leukemia, Acute\|Lymphoblastic Leukemia, Acute, Childhood\|Leukemia, Lymphoblastic, Acute, T Cell\|Leukemia, Lymphoblastic, Acute	August 24, 2010	Phase 1
NCT00109408	Hoffmann-La Roche	Rheumatoid Arthritis	July 2005	Phase 3
NCT00860574	Fred Hutchinson Cancer Center\|National Heart, Lung, and Blood Institute (NHLBI)\|National Cancer Institute (NCI)	Accelerated Phase Chronic Myelogenous Leukemia\|Adult Acute Lymphoblastic Leukemia in Remission\|Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|Blastic Phase Chronic Myelogenous Leukemia\|Childhood Acute Lymphoblastic Leukemia in Remission\|Childhood Acute Myeloid Leukemia in Remission\|Childhood Chronic Myelogenous Leukemia\|Childhood Myelodysplastic Syndromes\|Chronic Myelomonocytic Leukemia\|de Novo Myelodysplastic Syndromes\|Previously Treated Myelodysplastic Syndromes\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood Acute Myeloid Leukemia\|Secondary Myelodysplastic Syndromes\|Untreated Adult Acute Lymphoblastic Leukemia\|Untreated Childhood Acute Lymphoblastic Leukemia	February 2009	Phase 2
NCT00489203	Fred Hutchinson Cancer Center	Hematopoietic+Lymphoid Cancer\|Accelerated Phase Chronic Myelogenous Leukemia\|Adult Acute Lymphoblastic Leukemia in Remission\|Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|Atypical Chronic Myeloid Leukemia\|Blastic Phase Chronic Myelogenous Leukemia\|Childhood Acute Lymphoblastic Leukemia in Remission\|Childhood Acute Myeloid Leukemia in Remission\|Childhood Chronic Myelogenous Leukemia\|Childhood Myelodysplastic Syndromes\|Chronic Eosinophilic Leukemia\|Chronic Myelomonocytic Leukemia\|Chronic Neutrophilic Leukemia\|Chronic Phase Chronic Myelogenous Leukemia\|Contiguous Stage II Adult Burkitt Lymphoma\|Contiguous Stage II Adult Diffuse Large Cell Lymphoma\|Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma\|Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma\|Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma\|Contiguous Stage II Adult Lymphoblastic Lymphoma\|Contiguous Stage II Grade 1 Follicular Lymphoma\|Contiguous Stage II Grade 2 Follicular Lymphoma\|Contiguous Stage II Grade 3 Follicular Lymphoma\|Contiguous Stage II Mantle Cell Lymphoma\|Contiguous Stage II Marginal Zone Lymphoma\|Contiguous Stage II Small Lymphocytic Lymphoma\|de Novo Myelodysplastic Syndromes\|Essential Thrombocythemia\|Extramedullary Plasmacytoma\|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue\|Graft Versus Host Disease\|Isolated Plasmacytoma of Bone\|Juvenile Myelomonocytic Leukemia\|Meningeal Chronic Myelogenous Leukemia\|Myelodysplastic+Myeloproliferative Disease, Unclassifiable\|Nodal Marginal Zone B-cell Lymphoma\|Noncontiguous Stage II Adult Burkitt Lymphoma\|Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma\|Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma\|Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma\|Noncontiguous Stage II Adult Lymphoblastic Lymphoma\|Noncontiguous Stage II Grade 1 Follicular Lymphoma\|Noncontiguous Stage II Grade 2 Follicular Lymphoma\|Noncontiguous Stage II Grade 3 Follicular Lymphoma\|Noncontiguous Stage II Mantle Cell Lymphoma\|Noncontiguous Stage II Marginal Zone Lymphoma\|Noncontiguous Stage II Small Lymphocytic Lymphoma\|Previously Treated Myelodysplastic Syndromes\|Primary Myelofibrosis\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Adult Burkitt Lymphoma\|Recurrent Adult Diffuse Large Cell Lymphoma\|Recurrent Adult Diffuse Mixed Cell Lymphoma\|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma\|Recurrent Adult Grade III Lymphomatoid Granulomatosis\|Recurrent Adult Hodgkin Lymphoma\|Recurrent Adult Lymphoblastic Lymphoma\|Recurrent Adult T-cell Leukemia+Lymphoma\|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma\|Recurrent Grade 1 Follicular Lymphoma\|Recurrent Grade 2 Follicular Lymphoma\|Recurrent Grade 3 Follicular Lymphoma\|Recurrent Mantle Cell Lymphoma\|Recurrent Marginal Zone Lymphoma\|Recurrent Mycosis Fungoides+Sezary Syndrome\|Recurrent Small Lymphocytic Lymphoma\|Recurrent+Refractory Childhood Hodgkin Lymphoma\|Refractory Chronic Lymphocytic Leukemia\|Refractory Hairy Cell Leukemia\|Relapsing Chronic Myelogenous Leukemia\|Secondary Myelodysplastic Syndromes\|Stage I Adult Burkitt Lymphoma\|Stage I Adult Diffuse Large Cell Lymphoma\|Stage I Adult Diffuse Mixed Cell Lymphoma\|Stage I Adult Diffuse Small Cleaved Cell Lymphoma\|Stage I Adult Hodgkin Lymphoma\|Stage I Adult Immunoblastic Large Cell Lymphoma\|Stage I Adult Lymphoblastic Lymphoma\|Stage I Adult T-cell Leukemia+Lymphoma\|Stage I Childhood Hodgkin Lymphoma\|Stage I Chronic Lymphocytic Leukemia\|Stage I Cutaneous T-cell Non-Hodgkin Lymphoma\|Stage I Grade 1 Follicular Lymphoma\|Stage I Grade 2 Follicular Lymphoma\|Stage I Grade 3 Follicular Lymphoma\|Stage I Mantle Cell Lymphoma\|Stage I Marginal Zone Lymphoma\|Stage I Multiple Myeloma\|Stage I Mycosis Fungoides+Sezary Syndrome\|Stage I Small Lymphocytic Lymphoma\|Stage II Adult Hodgkin Lymphoma\|Stage II Adult T-cell Leukemia+Lymphoma\|Stage II Chronic Lymphocytic Leukemia\|Stage II Cutaneous T-cell Non-Hodgkin Lymphoma\|Stage II Multiple Myeloma\|Stage II Mycosis Fungoides+Sezary Syndrome\|Stage III Adult Burkitt Lymphoma\|Stage III Adult Diffuse Large Cell Lymphoma\|Stage III Adult Diffuse Mixed Cell Lymphoma\|Stage III Adult Diffuse Small Cleaved Cell Lymphoma\|Stage III Adult Hodgkin Lymphoma\|Stage III Adult Immunoblastic Large Cell Lymphoma\|Stage III Adult Lymphoblastic Lymphoma\|Stage III Adult T-cell Leukemia+Lymphoma\|Stage III Chronic Lymphocytic Leukemia\|Stage III Cutaneous T-cell Non-Hodgkin Lymphoma\|Stage III Grade 1 Follicular Lymphoma\|Stage III Grade 2 Follicular Lymphoma\|Stage III Grade 3 Follicular Lymphoma\|Stage III Mantle Cell Lymphoma\|Stage III Marginal Zone Lymphoma\|Stage III Multiple Myeloma\|Stage III Mycosis Fungoides+Sezary Syndrome\|Stage III Small Lymphocytic Lymphoma\|Stage IV Adult Burkitt Lymphoma\|Stage IV Adult Diffuse Large Cell Lymphoma\|Stage IV Adult Diffuse Mixed Cell Lymphoma\|Stage IV Adult Diffuse Small Cleaved Cell Lymphoma\|Stage IV Adult Hodgkin Lymphoma\|Stage IV Adult Immunoblastic Large Cell Lymphoma\|Stage IV Adult Lymphoblastic Lymphoma\|Stage IV Adult T-cell Leukemia+Lymphoma\|Stage IV Chronic Lymphocytic Leukemia\|Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma\|Stage IV Grade 1 Follicular Lymphoma\|Stage IV Grade 2 Follicular Lymphoma\|Stage IV Grade 3 Follicular Lymphoma\|Stage IV Marginal Zone Lymphoma\|Stage IV Mycosis Fungoides+Sezary Syndrome\|Stage IV Small Lymphocytic Lymphoma	April 2007	Phase 2
NCT01376427	PETHEMA Foundation	Acute Lymphoblastic Leukemia Ph Positive	January 2007	Not Applicable
NCT00003536	Burzynski Research Institute\|National Cancer Institute (NCI)	Stage IV Breast Cancer\|Recurrent Breast Cancer		Phase 2
NCT01802593	Prof. Arie Levine\|Wolfson Medical Center	Crohn´s Disease	February 2013	Phase 4
NCT01007435	Hoffmann-La Roche	Rheumatoid Arthritis	October 31, 2009	Phase 3
NCT04237103	University Hospital, Bordeaux	Vitiligo	June 2, 2022	Phase 2
NCT04170504	Guang´anmen Hospital of China Academy of Chinese Medical Sciences	Rheumatoid Arthritis	November 2019	Phase 2\|Phase 3
NCT05543122	The Hospital for Sick Children\|St. Justine´s Hospital\|University of Waterloo	Breast Feeding	March 9, 2022
NCT01749111	Hospital Israelita Albert Einstein	Acute Myelogenous Leukemia\|Acute Lymphoid Leukemia\|Myeloproliferative Disease\|Myelodysplastic Syndrome\|Chronic Myeloid Leukemia\|Chronic Myelomonocytic Leukemia	December 2012	Phase 3
NCT00482833	Gruppo Italiano Malattie EMatologiche dell´Adulto\|Study Alliance Leukemia (SAL) Group	Leukemia	August 2007	Phase 3
NCT01557322	Pfizer	Rheumatoid Arthritis	October 2011
NCT00666354	MediQuest Therapeutics	Fingernail Psoriasis	October 2007	Phase 2
NCT00716248	Saitama Medical University\|Keio University	Rheumatoid Arthritis	January 2007	Phase 4
NCT02677181	Chinese PLA General Hospital\|309th Hospital of Chinese People´s Liberation Army\|Beijing Naval General Hospital\|Space Center Hospital, Peking University	aGVHD	January 2016	Phase 4
NCT00015873	Dutch Childhood Oncology Group	Leukemia	May 1999	Phase 3
NCT03602898	Fred Hutchinson Cancer Center	Acute Lymphoblastic Leukemia in Remission\|Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome\|Chronic Myelomonocytic Leukemia\|Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Hematopoietic and Lymphoid System Neoplasm\|Myelodysplastic Syndrome\|Myelofibrosis\|Myeloproliferative Neoplasm\|Recurrent Acute Myeloid Leukemia\|Recurrent Hodgkin Lymphoma\|Recurrent Non-Hodgkin Lymphoma\|Refractory Acute Myeloid Leukemia\|Therapy-Related Acute Myeloid Leukemia	June 1, 2021	Phase 2
NCT00409838	Bristol-Myers Squibb	Rheumatoid Arthritis	April 2007	Phase 3
NCT00161655	Wyeth is now a wholly owned subsidiary of Pfizer	Psoriasis\|Arthritis, Psoriatic	April 2005	Phase 4
NCT00003187	Virginia Commonwealth University\|National Cancer Institute (NCI)	Leukemia\|Lymphoma\|Myelodysplastic Syndromes	May 1995	Phase 2\|Phase 3
NCT00005977	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia\|Lymphoma	September 2000	Phase 3
NCT01741558	Instituto de Cardiologia do Rio Grande do Sul\|Instituto de Cardiologia de Santa Catarina	Myocardial Infarction	April 2013	Phase 2
NCT04308343	Assiut University	Ectopic Pregnancy	March 30, 2020	Not Applicable
NCT04944524	Shanghai Zhongshan Hospital	Granulomatosis With Polyangiitis	July 1, 2021	Phase 4
NCT01909427	Janssen Research & Development, LLC	Rheumatoid Arthritis	June 2013	Phase 2
NCT02451748	University of Illinois at Chicago\|UCB Pharma	Rheumatoid Arthritis	August 2015	Phase 4
NCT01087398	Tehran University of Medical Sciences	Osteopetrosis	September 2009	Phase 2\|Phase 3
NCT04971239	Assiut University	Psoriasis\|Methotrexate	October 1, 2021	Phase 4
NCT00003013	Fondazione IRCCS Istituto Nazionale dei Tumori, Milano\|National Cancer Institute (NCI)	Breast Cancer	October 1996	Phase 3
NCT02638948	Bristol-Myers Squibb	Rheumatoid Arthritis	February 16, 2016	Phase 2
NCT00230035	National Institute of Allergy and Infectious Diseases (NIAID)	Systemic Lupus Erythematosus	September 2005	Phase 2
NCT03112603	Incyte Corporation	Graft-versus-host Disease (GVHD)	March 7, 2018	Phase 3
NCT03737708	Astellas Pharma Korea, Inc.\|Astellas Pharma Inc	Rheumatoid Arthritis (RA)	February 13, 2019	Phase 4
NCT01709578	Sanofi\|Regeneron Pharmaceuticals	Rheumatoid Arthritis	October 2012	Phase 3
NCT01353859	Hoffmann-La Roche	Rheumatoid Arthritis	March 2011	Phase 3
NCT01976364	Pfizer	Arthritis, Psoriatic	February 17, 2014	Phase 3
NCT03817320	Therapeutic Advances in Childhood Leukemia Consortium\|Takeda\|Children´s Hospital Los Angeles	ALL, Childhood\|Lymphoblastic Lymphoma, Childhood\|Lymphoblastic Leukemia, Acute, Childhood	February 12, 2019	Phase 1\|Phase 2
NCT00000834	National Institute of Allergy and Infectious Diseases (NIAID)	HIV Infections		Phase 1
NCT00439283	Association de Recherche Clinique en Rhumatologie	Ankylosing Spondylitis	April 2003	Phase 3
NCT00651040	Institute of Rheumatology, Prague\|Karolinska Institutet	Polymyositis\|Dermatomyositis	May 2008	Phase 3
NCT02504268	Bristol-Myers Squibb	Rheumatoid Arthritis	September 3, 2015	Phase 3
NCT01706692	Swiss Dermatology Network for Targeted Therapies	Psoriasis	July 2011
NCT00406393	Medical College of Wisconsin\|National Heart, Lung, and Blood Institute (NHLBI)\|Blood and Marrow Transplant Clinical Trials Network\|National Cancer Institute (NCI)	Leukemia, Myelocytic, Acute\|Leukemia, Lymphocytic, Acute\|Leukemia, Myeloid, Chronic\|Myelodysplastic Syndromes	November 2006	Phase 3
NCT03994731	Horizon Therapeutics Ireland DAC\|Horizon Pharma Ireland, Ltd., Dublin Ireland	Gout	June 13, 2019	Phase 4
NCT02101853	National Cancer Institute (NCI)	Recurrent B Acute Lymphoblastic Leukemia	December 8, 2014	Phase 3
NCT03739853	University of Oxford	Psoriatic Arthritis	May 14, 2019	Phase 4
NCT01710358	Eli Lilly and Company	Rheumatoid Arthritis	October 2012	Phase 3
NCT01399372	Radiation Therapy Oncology Group\|National Cancer Institute (NCI)\|NRG Oncology	Chemotherapeutic Agent Toxicity\|Cognitive+Functional Effects\|Lymphoma\|Neurotoxicity\|Radiation Toxicity	September 2011	Phase 2
NCT00498589	Centre Hospitalier Universitaire de Besancon	Ulcerative Colitis	September 2007	Phase 2
NCT00002499	Grupo Argentino de Tratamiento de la Leucemia Aguda\|National Cancer Institute (NCI)	Leukemia	January 1990	Phase 2\|Phase 3
NCT02504359	OHSU Knight Cancer Institute\|Oregon Health and Science University	Plasma Cell Leukemia\|Recurrent Plasma Cell Myeloma	July 20, 2015	Phase 1
NCT02074319	Pakistan Institute of Living and Learning\|Abbasi Shaheed Hospital\|Dow University of Health Sciences\|Karwan e Hayat, Karachi, Pakistan\|Institute of Behavioural Sciences, Karachi, Pakistan	Schizophrenia\|Schizoaffective Disorder\|Schizophreniform Disorder	December 2013	Phase 1
NCT01323920	Dana-Farber Cancer Institute	Leukemia\|Lymphoma\|Myelodysplastic Syndrome	May 2011	Phase 2
NCT01079988	Merck KGaA, Darmstadt, Germany	Psoriasis	February 2004	Phase 4
NCT01884636	Astellas Pharma Global Development, Inc.\|Basilea Pharmaceutica International Ltd\|Astellas Pharma Inc	Pharmacokinetics of Isavuconazole\|Pharmacokinetics of Methotrexate\|Pharmacokinetics of 7-hydroxymethotrexate\|Healthy Subjects	February 2013	Phase 1
NCT02029599	Maoxiang Group Jilin Pharmaceutical Co., Ltd.	Rheumatoid Arthritis	March 2014	Phase 2
NCT01587989	Hoffmann-La Roche	Rheumatoid Arthritis	February 2012	Phase 3
NCT00121186	Southwest Oncology Group\|National Cancer Institute (NCI)	Lymphoma	July 2005	Phase 2
NCT03815448	Zhujiang Hospital\|Peking Union Medical College Hospital\|Third Affiliated Hospital, Sun Yat-Sen University\|Beijing Hospital\|Xuanwu Hospital, Beijing\|The First Affiliated Hospital of Anhui Medical University\|The Second People´s Hospital of GuangDong Province\|Peking University People´s Hospital\|Shenzhen Third People´s Hospital\|Central People´s Hospital of Zhanjiang	Knee Osteoarthritis\|Effusion Synovial\|Knee Pain	July 24, 2019	Not Applicable
NCT00002835	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Lymphoma	October 30, 1995	Phase 3
NCT01745055	Pfizer	Rheumatoid Arthritis	April 2005	Phase 1
NCT00014469	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)	Graft Versus Host Disease\|Leukemia\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Neoplasms	December 2000	Phase 2
NCT03369795	Sheba Medical Center	Schizophrenia	December 15, 2017	Phase 2
NCT00020943	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Lymphoma	June 2001	Phase 2
NCT00004323	National Center for Research Resources (NCRR)\|University of California, Los Angeles	Aplastic Anemia	February 1995	Phase 2
NCT02894645	National University Hospital, Singapore	Acute Lymphoblastic Leukemia (ALL)	October 2008	Phase 4
NCT01976182	Rennes University Hospital	Large Granular Lymphocytes Leukemia	November 26, 2013	Phase 2
NCT00574496	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)	Lymphoma	November 13, 2007	Phase 2
NCT03553238	Nanfang Hospital of Southern Medical University	Leukemia, Acute\|Leukemia, T Cell\|Leukemia, Lymphoblastic	February 14, 2016	Phase 2\|Phase 3
NCT00565409	Pfizer	Arthritis, Rheumatoid	March 2008	Phase 4
NCT00555048	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Graft Versus Host Disease\|Leukemia\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases	September 2007	Phase 1\|Phase 2
NCT04895423	National Medical Research Center for Children´s Health, Russian Federation	Atopic Dermatitis	November 25, 2021	Phase 4
NCT02097745	Hoffmann-La Roche\|Biogen	Rheumatoid Arthritis	June 2004	Phase 3
NCT03719560	Brown University	Diffuse Large B Cell Lymphoma	July 1, 2019	Phase 2
NCT02293902	Sanofi\|Regeneron Pharmaceuticals	Rheumatoid Arthritis	November 2014	Phase 3
NCT00002598	Memorial Sloan Kettering Cancer Center	Leukemia	June 1994	Phase 2
NCT02877303	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	B Acute Lymphoblastic Leukemia\|B Lymphoblastic Lymphoma	November 1, 2016	Phase 2
NCT00264550	Centocor, Inc.\|Schering-Plough	Rheumatoid Arthritis	December 2005	Phase 3
NCT03327116	University of Sao Paulo General Hospital\|FUNADERSP (Foundation for Research Support of the State of São Paulo)	Atopic Dermatitis	November 1, 2017	Not Applicable
NCT03892785	Centre Hospitalier Universitaire Dijon	Giant Cell Arteritis	January 27, 2020	Phase 3
NCT05600660	Second Affiliated Hospital, School of Medicine, Zhejiang University	Primary Central Nervous System Lymphoma	August 1, 2022	Phase 2
NCT01639521	University of Southern California\|National Cancer Institute (NCI)	Anterior Urethral Cancer\|Localized Transitional Cell Cancer of the Renal Pelvis and Ureter\|Posterior Urethral Cancer\|Recurrent Bladder Cancer\|Recurrent Urethral Cancer\|Regional Transitional Cell Cancer of the Renal Pelvis and Ureter\|Stage III Bladder Cancer\|Transitional Cell Carcinoma of the Bladder\|Ureter Cancer\|Urethral Cancer Associated With Invasive Bladder Cancer	May 2013	Phase 2
NCT01895764	University Hospital, Tours	Ankylosing Spondylitis	March 2013	Phase 4
NCT01661140	Hoffmann-La Roche	Rheumatoid Arthritis	September 2012	Phase 4
NCT00035074	National Center for Research Resources (NCRR)\|Crohn´s and Colitis Foundation	Inflammatory Bowel Disease		Not Applicable
NCT02795299	Bird Rock Bio, Inc.\|Techtrials Pesquisa e Tecnologia Ltda\|Pharmagenix	Rheumatoid Arthritis	January 2018	Phase 2
NCT04622956	University of Sao Paulo General Hospital\|Libbs Farmacêutica LTDA	Graft Vs Host Disease\|Hematopoietic Neoplasm	October 7, 2020	Phase 1\|Phase 2
NCT03680092	Dimitrios Tzachanis, MD PhD\|Bristol-Myers Squibb\|University of California, San Diego	GVHD\|Hematologic Neoplasms	November 26, 2019	Phase 2
NCT01314417	National Eye Institute (NEI)\|National Institutes of Health Clinical Center (CC)	Non-infectious Intermediate and Posterior Uveitis	February 2011	Phase 1\|Phase 2
NCT01619176	Chinese Academy of Sciences\|Shanghai Guanghua Hospital of Integrated Traditional Chinese and Western Medicine	Rheumatoid Arthritis	October 2012	Not Applicable
NCT00131053	Japan Adult Leukemia Study Group	Lymphoblastic Leukemia, Acute	September 2002	Phase 2
NCT00003436	Medical Research Council\|National Cancer Institute (NCI)	Leukemia\|Myelodysplastic Syndromes	July 1998	Phase 3
NCT00096135	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia	November 2004	Not Applicable
NCT01670084	Mayo Clinic	B-cell Adult Acute Lymphoblastic Leukemia\|Blastic Phase Chronic Myelogenous Leukemia\|Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Philadelphia Chromosome Positive Adult Precursor Acute Lymphoblastic Leukemia\|Untreated Adult Acute Lymphoblastic Leukemia	December 2012	Phase 2
NCT01235507	Hoffmann-La Roche	Rheumatoid Arthritis	February 2011	Phase 3
NCT04379219	Mansoura University	Cesarean Scar Pregnancy	December 1, 2019	Phase 4
NCT00053196	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Leukemia\|Lymphoma\|Multiple Myeloma\|Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myeloproliferative Neoplasms	December 2002	Phase 2
NCT00194779	University of Washington\|National Cancer Institute (NCI)	Estrogen Receptor-negative Breast Cancer\|Estrogen Receptor-positive Breast Cancer\|HER2-positive Breast Cancer\|Progesterone Receptor-negative Breast Cancer\|Progesterone Receptor-positive Breast Cancer\|Stage IA Breast Cancer\|Stage IB Breast Cancer\|Stage II Breast Cancer\|Stage IIIA Breast Cancer	October 2003	Phase 2
NCT02606539	Maher elesawi kamel elesawi\|Mansoura University	Gestational Trophoblastic Neoplasms	September 2015	Phase 2\|Phase 3
NCT05380934	Chia Tai Tianqing Pharmaceutical Group Co., Ltd.	Rheumatoid Arthritis	May 2022	Phase 1
NCT03131973	Bristol-Myers Squibb	Rheumatoid Arthritis	May 13, 2017	Phase 1
NCT02831855	Pfizer	Rheumatoid Arthritis	September 1, 2016	Phase 4
NCT00945724	International Extranodal Lymphoma Study Group (IELSG)	Large B-cell Diffuse Lymphoma of Testis	April 2009	Phase 2
NCT02706873	AbbVie	Rheumatoid Arthritis	February 23, 2016	Phase 3
NCT00707083	Prince of Wales Hospital, Shatin, Hong Kong	Leukemia	May 1, 2008	Phase 3
NCT01737671	M.D. Anderson Cancer Center	Brain Tumor\|Malignant Neoplasm of Fourth Ventricle of Brain	December 27, 2012	Early Phase 1
NCT00003209	European Organisation for Research and Treatment of Cancer - EORTC\|Medical Research Council	Cervical Cancer	December 1997	Phase 3
NCT02339441	University of Manchester	Early Diffuse Cutaneous Systemic Sclerosis	June 2010
NCT05279417	Aclaris Therapeutics, Inc.	Rheumatoid Arthritis	February 2, 2022	Phase 2
NCT04127721	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Allogeneic Stem Cell Transplant Recipient\|Hematologic and Lymphocytic Disorder\|Hematopoietic and Lymphoid Cell Neoplasm	September 22, 2020	Phase 2
NCT04845035	University of Michigan Rogel Cancer Center\|Takeda	Acute Lymphoblastic Leukemia	October 2022	Phase 2
NCT02845596	Michael Pulsipher, MD\|Children´s Hospital Los Angeles	Severe Aplastic Anemia	August 2016	Not Applicable
NCT00301912	University of California, San Francisco\|National Cancer Institute (NCI)	Anemia\|Chronic Myeloproliferative Disorders\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases	January 2002	Phase 2
NCT00317785	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Leukemia\|Lymphoma\|Myelodysplastic Syndromes	May 2005	Phase 2
NCT02422641	Wake Forest University Health Sciences\|Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	Metastatic Breast Cancer\|Leptomeningeal Disease	May 2015	Phase 2
NCT01664910	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Hematopoietic and Lymphoid Cell Neoplasm	October 29, 2012	Phase 1\|Phase 2
NCT00003592	Eastern Cooperative Oncology Group\|National Cancer Institute (NCI)	Head and Neck Cancer	September 1998	Phase 3
NCT04482543	Shahid Beheshti University of Medical Sciences	Proliferative Vitreoretinopathy	August 1, 2020	Phase 2\|Phase 3
NCT00005945	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia	June 2000	Phase 3
NCT00833053	Merck Sharp & Dohme LLC	Psoriasis	October 2009	Phase 3
NCT00402558	M.D. Anderson Cancer Center	Myelodysplastic Syndrome\|Leukemia	May 2006	Phase 1
NCT00004784	National Center for Research Resources (NCRR)\|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)\|University of Texas\|Office of Rare Diseases (ORD)	Liver Cirrhosis, Biliary	January 1994	Phase 3
NCT00146614	Dana-Farber Cancer Institute\|Brigham and Women´s Hospital\|Beth Israel Deaconess Medical Center\|Massachusetts General Hospital	Graft Versus Host Disease\|Hematologic Malignancies	July 2002	Phase 2
NCT00551460	Southwest Oncology Group\|National Cancer Institute (NCI)	Leukemia	November 2007	Phase 2
NCT02660762	Sun Yat-sen University	Leukaemia,Lymphoblastic	January 2016	Phase 2
NCT05476770	Therapeutic Advances in Childhood Leukemia Consortium	Hematologic Malignancy\|AML\|ALL\|BPDCN\|MDS\|Lymphoblastic Lymphoma\|Lymphoma, B-Cell\|Lymphoma, T-Cell\|Hodgkin Lymphoma\|Mixed Phenotype Acute Leukemia\|Acute Undifferentiated Leukemia	November 11, 2022	Phase 1
NCT02065713	Instituto de Medicina Molecular João Lobo Antunes\|Merck Sharp & Dohme LLC	Psoriatic Arthritis	August 2014	Phase 3
NCT01190930	Children´s Oncology Group\|National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|Adult B Lymphoblastic Lymphoma\|Ann Arbor Stage I B Lymphoblastic Lymphoma\|Ann Arbor Stage II B Lymphoblastic Lymphoma\|Childhood B Acute Lymphoblastic Leukemia\|Childhood B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1\|Childhood B Lymphoblastic Lymphoma\|Down Syndrome\|Hypodiploid B Acute Lymphoblastic Leukemia\|Philadelphia Chromosome Positive	August 9, 2010	Phase 3
NCT04192617	SinoMab BioScience Ltd	Rheumatoid Arthritis	December 31, 2014	Phase 2
NCT02772965	University of North Carolina, Chapel Hill\|Patient-Centered Outcomes Research Institute\|ImproveCareNow (ICN)\|The Leona M. and Harry B. Helmsley Charitable Trust\|Children´s Hospital Medical Center, Cincinnati\|Grifols Diagnostics Solutions, Inc\|National Institutes of Health (NIH)\|National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)	Pediatric Crohn´s Disease	October 2016	Phase 3
NCT05518383	Federal Research Institute of Pediatric Hematology, Oncology and Immunology	Non-hodgkin Lymphoma,B Cell\|Burkitt Lymphoma\|Primary Mediastinal Lymphoma\|Primary CNS Lymphoma\|Diffuse Large B-cell Lymphoma	May 25, 2022	Phase 4
NCT03172325	Cinnagen	Active Rheumatoid Arthritis	November 18, 2015	Phase 3
NCT00006033	H. Lee Moffitt Cancer Center and Research Institute\|National Cancer Institute (NCI)	Head and Neck Cancer	June 2000	Phase 2
NCT00012311	Herbert Irving Comprehensive Cancer Center\|National Cancer Institute (NCI)	Breast Cancer	January 2000	Phase 2
NCT05054426	Peking Union Medical College Hospital	Diffuse Large B Cell Lymphoma\|Central Nervous System Lymphoma	October 8, 2021	Phase 3
NCT01104025	Children´s Hospital Medical Center, Cincinnati	Hemophagocytic Lymphohistiocytosis	April 2010	Phase 2
NCT00809172	Hospices Civils de Lyon	Atopic Dermatitis	December 2008	Phase 3
NCT03792256	Children´s Oncology Group	Leukemia, Lymphocytic\|Lymphoblastic Lymphoma\|T-cell Lymphoma\|T-cell Leukemia\|Recurrent Disease\|Acute Leukemia	April 11, 2019	Phase 1
NCT04299971	Shanghai Zhongshan Hospital	Takayasu Arteritis\|Methotrexate\|Inhibition\|Treatment	March 1, 2020	Phase 4
NCT01617590	Shanxi Medical University	Rheumatoid Arthritis	May 2012	Not Applicable
NCT00741455	Dartmouth-Hitchcock Medical Center	Hematologic Malignancies	June 2004	Not Applicable
NCT00295997	University of California, San Francisco\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Kidney Cancer\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Neoplasms	May 2005	Not Applicable
NCT01379209	Regimmune Corporation	Graft Versus Host Disease	September 2011	Phase 1\|Phase 2
NCT02590510	Hui Bu\|Hebei Medical University	Meningeal Carcinomatosis	October 2015	Phase 4
NCT00695188	Ludwig-Boltzmann Institut fuer Rheumatologie, Balneologie und Rehabilitation	Rheumatoid Arthritis	May 2008	Phase 4
NCT00687648	National Cancer Centre, Singapore\|National Cancer Institute (NCI)	Breast Cancer	May 2008	Phase 2
NCT00006168	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	Liver Cirrhosis, Biliary	January 1994	Phase 3
NCT02710734	Fox Chase Cancer Center	Urothelial Carcinoma of the Bladder	February 24, 2016	Phase 2
NCT02825147	Ruijin Hospital	Nasal Type Extranodal NK+T-Cell Lymphoma	September 2013	Phase 2
NCT03980483	GlaxoSmithKline\|Iqvia Pty Ltd	Arthritis, Rheumatoid	May 16, 2019	Phase 3
NCT00016302	National Cancer Institute (NCI)	T-cell Childhood Acute Lymphoblastic Leukemia\|Untreated Childhood Acute Lymphoblastic Leukemia	April 2001	Not Applicable
NCT04571697	Janssen Research & Development, LLC	Dementia\|Alzheimer Disease	September 28, 2020
NCT01143337	Mitsubishi Tanabe Pharma Corporation	Rheumatoid Arthritis	June 2010	Phase 2
NCT03148860	Dr. Frank Behrens\|Janssen-Cilag Ltd.\|Fraunhofer Institute for Molecular Biology and Applied Ecology	Psoriatic Arthritis	December 15, 2016	Phase 3
NCT03495960	International Extranodal Lymphoma Study Group (IELSG)	Primary Central Nervous System Lymphoma	June 15, 2019	Phase 2
NCT02639650	Weiguo Lv\|Shandong University\|Huazhong University of Science and Technology\|First Affiliated Hospital of Zhongshan Medical University\|Women´s Hospital School Of Medicine Zhejiang University	Gestational Trophoblastic Neoplasms	March 1, 2016	Phase 3
NCT01856478	Boehringer Ingelheim	Head and Neck Neoplasms	May 23, 2013	Phase 3
NCT00210314	International Extranodal Lymphoma Study Group (IELSG)	Lymphoma, B Cell	July 2003	Phase 2
NCT02112916	National Cancer Institute (NCI)	Adult T Acute Lymphoblastic Leukemia\|Ann Arbor Stage II Adult Lymphoblastic Lymphoma\|Ann Arbor Stage II Childhood Lymphoblastic Lymphoma\|Ann Arbor Stage III Adult Lymphoblastic Lymphoma\|Ann Arbor Stage III Childhood Lymphoblastic Lymphoma\|Ann Arbor Stage IV Adult Lymphoblastic Lymphoma\|Ann Arbor Stage IV Childhood Lymphoblastic Lymphoma\|Childhood T Acute Lymphoblastic Leukemia	September 30, 2014	Phase 3
NCT00003273	NYU Langone Health	Brain and Central Nervous System Tumors\|Neuroblastoma\|Retinoblastoma\|Sarcoma	November 1997	Phase 2
NCT01085617	University College, London	Leukemia\|Mucositis\|Oral Complications	December 2010	Phase 3
NCT03703271	Women´s Hospital School Of Medicine Zhejiang University\|Sun Yat-sen University\|Huazhong University of Science and Technology\|Qilu Hospital of Shandong University	Gestational Trophoblastic Neoplasia	March 1, 2019	Phase 3
NCT05393050	Quan Jiang\|Guang´anmen Hospital of China Academy of Chinese Medical Sciences	Rheumatoid Arthritis	July 2022	Phase 4
NCT03571321	University of Chicago\|Incyte Corporation	Acute Lymphoblastic Leukemia\|ALL, Childhood\|ALL	May 28, 2019	Phase 1
NCT01005914	OHSU Knight Cancer Institute\|National Cancer Institute (NCI)	Leukemia	June 2009	Phase 2
NCT00003376	Eastern Cooperative Oncology Group\|National Cancer Institute (NCI)\|Cancer and Leukemia Group B	Bladder Cancer\|Transitional Cell Cancer of the Renal Pelvis and Ureter\|Urethral Cancer	September 1998	Phase 3
NCT03217734	Jeffrey J Crowley MD\|AbbVie\|Bakersfield Dermatology & Skin Cancer Medical Group	Psoriasis	April 10, 2017	Phase 2\|Phase 3
NCT00588536	Memorial Sloan Kettering Cancer Center	Langerhans Cell Histiocytosis	January 1995	Phase 2
NCT00848354	Pfizer\|Amgen	Rheumatoid Arthritis	June 2009	Phase 4
NCT02557100	Bristol-Myers Squibb	Rheumatoid Arthritis	November 19, 2015	Phase 4
NCT00006054	Fairview University Medical Center\|Office of Rare Diseases (ORD)	Immunologic Deficiency Syndromes\|Chediak-Higashi Syndrome\|Common Variable Immunodeficiency\|Graft Versus Host Disease\|X-Linked Lymphoproliferative Syndrome\|Familial Erythrophagocytic Lymphohistiocytosis\|Hemophagocytic Lymphohistiocytosis\|X-linked Agammaglobulinemia\|Wiskott-Aldrich Syndrome\|Chronic Granulomatous Disease\|X-linked Hyper IgM Syndrome\|Severe Combined Immunodeficiency\|Leukocyte Adhesion Deficiency Syndrome\|Virus-Associated Hemophagocytic Syndrome	March 2000	Not Applicable
NCT00873093	National Cancer Institute (NCI)	B-cell Adult Acute Lymphoblastic Leukemia\|B-cell Childhood Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Lymphoblastic Lymphoma\|Recurrent Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood Lymphoblastic Lymphoma\|T-cell Adult Acute Lymphoblastic Leukemia\|T-cell Childhood Acute Lymphoblastic Leukemia	March 2009	Phase 2
NCT00002582	Institute of Cancer Research, United Kingdom\|Cancer Research Campaign Clinical Trials Centre\|Scottish Cancer Therapy Network\|Yorkshire Regional Clinical Trials Research Unit\|National Cancer Institute (NCI)	Breast Cancer	June 1993	Phase 3
NCT02385110	M.D. Anderson Cancer Center	Leukemia	September 23, 2015	Phase 2
NCT00002531	Johann Wolfgang Goethe University Hospital\|National Cancer Institute (NCI)	Leukemia	January 1993	Phase 2
NCT05445440	Bristol-Myers Squibb	Healthy Participants	September 6, 2022	Phase 1
NCT01142726	Bristol-Myers Squibb	Rheumatoid Arthritis	December 2010	Phase 3
NCT00309569	Austrian Breast & Colorectal Cancer Study Group	Early Stage Breast Cancer	October 1991	Phase 3
NCT03914625	National Cancer Institute (NCI)	B Acute Lymphoblastic Leukemia\|B Lymphoblastic Lymphoma\|Down Syndrome	June 28, 2019	Phase 3
NCT00309478	Austrian Breast & Colorectal Cancer Study Group\|AstraZeneca	Early-stage Breast Cancer	December 1990	Phase 3
NCT01829295	University of California, San Francisco\|Aravind Eye Hospitals, India\|Oregon Health and Science University\|Asociación para Evitar la Ceguera en México\|Royal Victoria Eye and Ear Hospital\|Northwestern University\|National Eye Institute (NEI)\|King Khaled Eye Specialist Hospital	Uveitis	August 2013	Phase 3
NCT02177071	Groupe d´Etude Therapeutique des Affections Inflammatoires Digestives\|Saint-Louis Hospital, Paris, France	Crohn´s Disease	October 9, 2015	Phase 4
NCT00558519	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Leukemia	March 12, 2008	Phase 2
NCT03736161	Globe Pharmaceuticals Limited	Psoriatic Arthritis	September 15, 2017	Phase 3
NCT02046603	Hoffmann-La Roche	Rheumatoid Arthritis	March 4, 2014	Phase 3
NCT02916979	Dartmouth-Hitchcock Medical Center	Leukemia, Lymphoid\|Leukemia, Myeloid\|Myelodysplastic Syndromes\|Myelofibrosis\|Lymphoma, Malignant\|Multiple Myeloma\|Waldenstrom Macroglobulinemia	September 6, 2016	Phase 1
NCT05427175	Aswan University Hospital	Psoriasis	January 10, 2022	Phase 4
NCT02905110	The University of Texas Health Science Center, Houston	Brain Tumor Recurrent	October 2016	Early Phase 1
NCT00445770	Pfizer	Arthritis, Rheumatoid	July 2006	Phase 3
NCT00878254	University of Miami	Mantle-Cell Lymphoma	March 25, 2009	Phase 2
NCT02313870	University Hospital, Montpellier	Bullous Pemphigoid	January 22, 2008	Phase 3
NCT00003061	European Organisation for Research and Treatment of Cancer - EORTC	Lymphoma	July 1997	Phase 2
NCT00057811	Children´s Oncology Group\|National Cancer Institute (NCI)	Childhood Burkitt Lymphoma\|Childhood Diffuse Large Cell Lymphoma\|Childhood Immunoblastic Large Cell Lymphoma\|Stage I Childhood Large Cell Lymphoma\|Stage I Childhood Small Noncleaved Cell Lymphoma\|Stage II Childhood Large Cell Lymphoma\|Stage II Childhood Small Noncleaved Cell Lymphoma\|Stage III Childhood Large Cell Lymphoma\|Stage III Childhood Small Noncleaved Cell Lymphoma\|Stage IV Childhood Large Cell Lymphoma\|Stage IV Childhood Small Noncleaved Cell Lymphoma\|Untreated Childhood Acute Lymphoblastic Leukemia	June 2004	Phase 2
NCT04440267	wang, jianxiang\|Institute of Hematology & Blood Diseases Hospital	Acute Leukemia of Ambiguous Lineage	June 20, 2020	Phase 2
NCT02037191	University Hospital, Rouen	ALOPECIA AREATA	February 2014	Phase 3
NCT00422227	Wyeth is now a wholly owned subsidiary of Pfizer	Rheumatoid Arthritis	June 2007	Phase 4
NCT00462345	Hoffmann-La Roche	Rheumatoid Arthritis	June 2007	Phase 4
NCT00195494	Wyeth is now a wholly owned subsidiary of Pfizer	Rheumatoid Arthritis	November 2004	Phase 4
NCT01861002	Therapeutic Advances in Childhood Leukemia Consortium\|Gateway for Cancer Research	Lymphoblastic Leukemia, Acute, Childhood\|Myelogenous Leukemia, Acute, Childhood	May 22, 2013	Phase 1
NCT00002498	Leiden University Medical Center\|National Cancer Institute (NCI)	Breast Cancer	July 1992	Phase 2
NCT00002514	Eastern Cooperative Oncology Group\|National Cancer Institute (NCI)\|Medical Research Council	Leukemia	April 1993	Phase 3
NCT01446211	Nordic Pharma SAS	Wegeners Granulomatosis	November 2011	Phase 3
NCT00578903	Baylor College of Medicine\|The Methodist Hospital Research Institute\|Center for Cell and Gene Therapy, Baylor College of Medicine	Aplastic Anemia	February 2002	Phase 2
NCT00245037	OHSU Knight Cancer Institute\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Neoplasms\|Precancerous Condition	June 2005	Phase 1\|Phase 2
NCT02122081	Ohio State University Comprehensive Cancer Center	Adult Acute Lymphoblastic Leukemia in Remission\|Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|de Novo Myelodysplastic Syndromes\|Previously Treated Myelodysplastic Syndromes\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Myeloid Leukemia\|Secondary Myelodysplastic Syndromes\|Untreated Adult Acute Lymphoblastic Leukemia\|Untreated Adult Acute Myeloid Leukemia	July 27, 2015	Not Applicable
NCT00002494	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Leukemia\|Lymphoma	May 1992	Phase 2
NCT01758198	Bristol-Myers Squibb\|Ono Pharmaceutical Co. Ltd	Rheumatoid Arthritis	April 11, 2013	Phase 4
NCT00162292	Bristol-Myers Squibb	Rheumatoid Arthritis	November 2005	Phase 1
NCT04329325	Memorial Sloan Kettering Cancer Center\|Amgen	Acute Lymphoblastic Leukemia\|Philadelphia Chromosome-Positive	March 30, 2020	Phase 2
NCT01027000	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)\|Genentech, Inc.\|Biologics, Inc.	Leukemia\|Lymphoma	February 2010	Phase 2
NCT00846703	Sun Yat-sen University	Acute Lymphoblastic Leukemia	July 2008	Phase 4
NCT00002676	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Lymphoma	July 1995	Phase 2
NCT00003870	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Leukemia	February 1999	Phase 2
NCT00973479	Centocor, Inc.\|Schering-Plough	Arthritis, Rheumatoid	September 2009	Phase 3
NCT00557193	Children´s Oncology Group\|National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|Acute Undifferentiated Leukemia\|Childhood T Acute Lymphoblastic Leukemia	January 14, 2008	Phase 3
NCT00526175	PETHEMA Foundation	Acute Lymphoblastic Leukemia	June 2001	Phase 4
NCT00001498	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Breast Cancer\|Breast Neoplasms	February 1996	Phase 2
NCT00317876	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Fanconi Anemia	June 1998	Phase 1
NCT00536978	M.D. Anderson Cancer Center	Lymphoma\|Leukemia	September 2007	Phase 2
NCT01810926	Franco Locatelli\|University of Milano Bicocca\|medac GmbH\|Fresenius AG\|Bambino Gesù Hospital and Research Institute	Graft Versus Host Disease	September 2011	Phase 2
NCT00002700	European Organisation for Research and Treatment of Cancer - EORTC\|Acute Leukemia French Association	Leukemia\|Lymphoma	August 1995	Phase 3
NCT00003700	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Leukemia	January 1999	Phase 2
NCT02383901	Isofol Medical AB	Osteosarcoma	September 2014
NCT00002701	European Organisation for Research and Treatment of Cancer - EORTC\|Gruppo Italiano Malattie EMatologiche dell´Adulto\|National Cancer Institute (NCI)	Leukemia	October 1995	Phase 3
NCT00450801	University of Miami	Lymphoma	April 2004	Phase 2
NCT00448357	UNC Lineberger Comprehensive Cancer Center\|National Cancer Institute (NCI)\|Otsuka America Pharmaceutical	Chronic Myeloproliferative Disorders\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes	October 2005	Phase 1\|Phase 2
NCT03518242	Fred Hutchinson Cancer Center\|GlaxoSmithKline	Breast Cancer Female\|Anatomic Stage IIB Breast Cancer AJCC v8\|Anatomic Stage III Breast Cancer AJCC v8\|Anatomic Stage IIIA Breast Cancer AJCC v8\|Anatomic Stage IIIB Breast Cancer AJCC v8\|Anatomic Stage IIIC Breast Cancer AJCC v8\|Invasive Breast Carcinoma\|Prognostic Stage IIB Breast Cancer AJCC v8\|Prognostic Stage III Breast Cancer AJCC v8\|Prognostic Stage IIIA Breast Cancer AJCC v8\|Prognostic Stage IIIB Breast Cancer AJCC v8\|Prognostic Stage IIIC Breast Cancer AJCC v8	June 6, 2018	Phase 1
NCT02535806	Children´s Mercy Hospital Kansas City\|Millennium Pharmaceuticals, Inc.	Acute Lymphoblastic Leukemia\|Lymphoblastic Lymphoma	July 2015	Phase 2
NCT01056614	Fred Hutchinson Cancer Center\|National Heart, Lung, and Blood Institute (NHLBI)\|National Cancer Institute (NCI)	Accelerated Phase Chronic Myelogenous Leukemia\|Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|Blastic Phase Chronic Myelogenous Leukemia\|Childhood Acute Myeloid Leukemia in Remission\|Childhood Chronic Myelogenous Leukemia\|Childhood Myelodysplastic Syndromes\|Chronic Phase Chronic Myelogenous Leukemia\|de Novo Myelodysplastic Syndromes\|Hematopoietic+Lymphoid Cancer\|Myelodysplastic+Myeloproliferative Neoplasm, Unclassifiable\|Previously Treated Myelodysplastic Syndromes\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Childhood Acute Myeloid Leukemia\|Relapsing Chronic Myelogenous Leukemia	September 2004	Phase 2
NCT03757364	Ryszard Górecki\|University of Warmia and Mazury	Nail Psoriasis	January 7, 2018
NCT01659242	Singapore General Hospital	Rheumatoid Arthritis	July 2012	Phase 4
NCT02714634	University Hospital, Strasbourg, France	Rheumatoid Arthritis\|Insufficient Response to Methotrexate or Leflunomide	March 30, 2016	Phase 4
NCT01633983	Edward Averbukh\|Hadassah Medical Organization	Central Serous Chorioretinopathy	August 2012	Phase 2
NCT01876004	Federal University of São Paulo	Ectopic Pregnancy	September 2011	Phase 4
NCT02655705	Seoul National University Hospital	Psoriasis	August 2014	Phase 4
NCT02940561	Amneal Pharmaceuticals, LLC\|Accutest Research Laboratories (I) Pvt. Ltd.	Psoriasis\|Rheumatoid Arthritis	August 2016	Phase 1
NCT04356222	Hui Bu\|Hebei Medical University	Leptomeningeal Metastasis\|Durvalumab	June 2020	Phase 4
NCT00002704	National Cancer Institute (NCI)	Leukemia	January 1996	Phase 2
NCT02714998	Ege University	Ectopic Pregnancy\|Infertility	January 2013	Not Applicable
NCT00194272	University of Pennsylvania\|Bill and Melinda Gates Foundation	Ectopic Pregnancy	March 2001	Phase 3
NCT00993317	Korea Otsuka Pharmaceutical Co., Ltd.	Rheumatoid Arthritis	October 2009	Phase 3
NCT01491958	Ohio State University Comprehensive Cancer Center	Acute Myelogenous Leukemia\|Acute Lymphocytic Leukemia\|Myelodysplastic Syndrome	December 10, 2011	Phase 2
NCT00976599	Pfizer	Rheumatoid Arthritis	November 2009	Phase 2
NCT02611492	Assistance Publique - Hôpitaux de Paris	Philadelphia Chromosome Positive Adult Acute Lymphoblastic Leukemia	April 2016	Phase 3
NCT00344253	Heidelberg University\|Serono GmbH	Uveitis, Intermediate\|Macular Edema\|Multiple Sclerosis	March 2006	Phase 3
NCT00408005	National Cancer Institute (NCI)	T Acute Lymphoblastic Leukemia\|T Lymphoblastic Lymphoma	January 22, 2007	Phase 3
NCT01788501	Seoul National University Hospital	Graft vs Host Disease	November 2011	Phase 2\|Phase 3
NCT00299182	M.D. Anderson Cancer Center\|Amgen	Lymphoma	March 2006	Phase 1\|Phase 2
NCT00129506	Wiebe, Ellen, M.D.\|Ibis Reproductive Health	Unwanted Pregnancies	May 2005	Phase 4
NCT02487069	Nanfang Hospital of Southern Medical University\|Guangdong Provincial People´s Hospital\|Third Affiliated Hospital, Sun Yat-Sen University\|Guangzhou General Hospital of Guangzhou Military Command\|Guangzhou First People´s Hospital\|Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University\|Zhujiang Hospital\|Tongji Hospital\|Wuhan Union Hospital, China\|Fujian Medical University Union Hospital\|First Affiliated Hospital of Guangxi Medical University\|Xiangya Hospital of Central South University	Acute Leukemia\|Chronic Myeloid Leukemia\|Myelodysplastic Syndrome	June 2015	Not Applicable
NCT02046616	Hoffmann-La Roche	Rheumatoid Arthritis	May 28, 2014	Phase 3
NCT00803010	H. Lee Moffitt Cancer Center and Research Institute	Acute Graft Versus Host Disease	September 2008	Phase 2
NCT01363128	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|Adult Acute Lymphoblastic Leukemia in Complete Remission\|Burkitt Leukemia\|Burkitt Lymphoma\|CD20 Positive\|Childhood Acute Lymphoblastic Leukemia in Complete Remission\|Lymphoblastic Lymphoma	July 12, 2011	Phase 2
NCT00718718	Centocor, Inc.	Arthritis, Rheumatoid	August 11, 2008	Phase 2
NCT05263505	Washington University School of Medicine\|Eli Lilly and Company	Mucous Membrane Pemphigoid\|Cicatrizing Conjunctivitis	February 21, 2022	Phase 2
NCT04453345	Institute of Hematology & Blood Diseases Hospital\|The First Affiliated Hospital of Nanchang University\|First Affiliated Hospital of Guangxi Medical University\|Henan Cancer Hospital\|The First Hospital of Jilin University\|Central South University\|Tianjin First Central Hospital	T-LGL Leukemia\|Clpd-Nk	May 20, 2013	Phase 2\|Phase 3
NCT00003650	UNICANCER	Lymphoma	February 1997	Phase 3
NCT02052167	medac GmbH\|PPD	Juvenile Idiopathic Arthritis	April 2014	Early Phase 1
NCT00252668	Wyeth is now a wholly owned subsidiary of Pfizer	Rheumatoid Arthritis	June 2004	Phase 4
NCT01345682	Boehringer Ingelheim	Head and Neck Neoplasms\|Carcinoma, Squamous Cell	January 5, 2012	Phase 3
NCT02762838	Biocad	Rheumatoid Arthritis	January 2016	Phase 3
NCT02715947	Central South University	Psoriasis Vulgaris	December 2015	Phase 2
NCT04396223	Hospices Civils de Lyon\|Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany	Gestational Trophoblastic Neoplasias (GTN)	February 12, 2020	Phase 1\|Phase 2
NCT02299999	UNICANCER\|Fondation ARC\|AstraZeneca	Metastatic Breast Cancer	April 7, 2014	Phase 2
NCT00002816	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia	December 1996	Phase 3
NCT00563589	Hospital Authority, Hong Kong\|Hoffmann-La Roche	Graft vs Host Disease\|Hematopoietic Stem Cell Transplantation	August 2003	Not Applicable
NCT00002919	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)	Bladder Cancer	November 1996	Phase 2
NCT03257852	Astellas Pharma Inc	Rheumatoid Arthritis (RA)	September 29, 2017	Phase 2
NCT00336024	Children´s Oncology Group\|National Cancer Institute (NCI)	Untreated Childhood Medulloblastoma\|Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor	October 22, 2007	Phase 3
NCT00081055	Mesoblast International Sàrl\|National Cancer Institute (NCI)\|Mesoblast, Ltd.	Graft Versus Host Disease\|Leukemia\|Myelodysplastic Syndromes		Phase 2
NCT00002547	Barbara Ann Karmanos Cancer Institute\|National Cancer Institute (NCI)	Leukemia\|Myelodysplastic Syndromes	August 1987	Phase 2
NCT00918554	Assistance Publique - Hôpitaux de Paris	Sarcoid-associated Uveitis\|Ocular Sarcoidosis\|Macular Edema	September 2009	Phase 4
NCT00180908	Gustave Roussy, Cancer Campus, Grand Paris	Osteosarcoma\|Localised High Grade Osteosarcoma of the Limbs	June 1994	Phase 3
NCT05522582	Yancheng First People´s Hospital	Solid Tumors	November 15, 2021	Phase 2
NCT03635957	Horizon Therapeutics Ireland DAC\|Horizon Pharma Ireland, Ltd., Dublin Ireland	Gout	September 26, 2018	Phase 4
NCT00287924	Children´s Cancer and Leukaemia Group\|National Cancer Institute (NCI)	Brain and Central Nervous System Tumors	March 2005	Phase 2
NCT03505008	Keio University\|Eisai Co., Ltd.	Rheumatoid Arthritis	April 18, 2018	Phase 4
NCT00492856	Southwest Oncology Group\|National Cancer Institute (NCI)	Leukemia	June 2007	Phase 3
NCT00029523	Pacira Pharmaceuticals, Inc	Meningeal Neoplasms	April 2001	Phase 4
NCT05315128	Zagazig University	Non-melanoma Skin Cancers	July 6, 2020	Phase 2
NCT01960283	University Hospital, Tours	Chronic Urticaria	November 2011	Phase 3
NCT00299104	Genentech, Inc.\|Hoffmann-La Roche	Rheumatoid Arthritis	January 2006	Phase 3
NCT00002768	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Leukemia	June 1996	Phase 2
NCT00003701	Eastern Cooperative Oncology Group\|National Cancer Institute (NCI)	Bladder Cancer\|Urethral Cancer	March 1999	Phase 3
NCT00068250	Radiation Therapy Oncology Group\|National Cancer Institute (NCI)\|NRG Oncology	Brain and Central Nervous System Tumors\|Lymphoma	July 2003	Phase 1\|Phase 2
NCT00234936	Abbott	Rheumatoid Arthritis	December 2003	Phase 3
NCT00458250	Tehran University of Medical Sciences	Leukemia, Myeloid, Acute\|Leukemia, Lymphoblastic, Acute	September 2006	Phase 1
NCT03684980	Memorial Sloan Kettering Cancer Center\|University of Alabama at Birmingham	Central Nervous System Lymphoma	November 14, 2018	Early Phase 1
NCT00213538	University Hospital, Rouen	Rheumatoid Arthritis	June 2003
NCT00732875	Merck Sharp & Dohme LLC	Arthritis, Rheumatoid	August 2006	Phase 3
NCT00659412	Astellas Pharma Inc\|Biogen	Psoriatic Arthritis	September 2003	Phase 2
NCT01858740	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)\|National Heart, Lung, and Blood Institute (NHLBI)	Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Acute Biphenotypic Leukemia\|Acute Leukemia of Ambiguous Lineage\|Acute Undifferentiated Leukemia\|Adult Acute Lymphoblastic Leukemia in Remission\|Adult Acute Myeloid Leukemia in Remission\|Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Childhood Acute Lymphoblastic Leukemia in Remission\|Childhood Acute Myeloid Leukemia in Remission\|Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Myelodysplastic Syndrome With Excess Blasts-1\|Myelodysplastic Syndrome With Excess Blasts-2\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood Acute Myeloid Leukemia\|Refractory Adult Acute Lymphoblastic Leukemia\|Refractory Childhood Acute Lymphoblastic Leukemia	December 17, 2013	Phase 2
NCT03263572	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)\|Amgen\|Takeda	Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Acute Lymphoblastic Leukemia\|BCR-ABL1 Fusion Protein Expression\|Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Philadelphia Chromosome Positive\|Recurrent Acute Lymphoblastic Leukemia\|Refractory Acute Lymphoblastic Leukemia\|t(9;22)	November 29, 2017	Phase 2
NCT00959036	Ablynx	Active Rheumatoid Arthritis	September 2009	Phase 1\|Phase 2
NCT00112645	Milton S. Hershey Medical Center\|National Cancer Institute (NCI)	Neuroblastoma\|Sarcoma\|Unspecified Childhood Solid Tumor, Protocol Specific	April 2005	Phase 1
NCT02777736	Czech Lymphoma Study Group	Diffuse Large B-cell Lymphoma	July 2015	Phase 3
NCT00002831	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Leukemia	August 1, 1995	Phase 1\|Phase 2
NCT02076659	Philogen S.p.A.	Rheumatoid Arthritis	September 2011	Phase 1
NCT01629511	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Allogeneic Hematopoietic Stem Cell Transplantation Recipient\|Chronic Lymphocytic Leukemia\|Prolymphocytic Leukemia\|Richter Syndrome	November 21, 2012	Phase 1\|Phase 2
NCT04360785	Assistance Publique - Hôpitaux de Paris	Spondyloarthritis	June 2020	Not Applicable
NCT01225874	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia	December 1999	Not Applicable
NCT00890656	M.D. Anderson Cancer Center\|Enzon Pharmaceuticals, Inc.	Acute Lymphoblastic Leukemia	June 2003	Phase 2
NCT02883049	National Cancer Institute (NCI)	B Acute Lymphoblastic Leukemia\|Central Nervous System Leukemia\|Ph-Like Acute Lymphoblastic Leukemia\|Testicular Leukemia	February 27, 2012	Phase 3
NCT00354107	National Cancer Institute (NCI)	Anaplastic Large Cell Lymphoma\|Recurrent Childhood Anaplastic Large Cell Lymphoma	January 2007	Phase 1\|Phase 2
NCT01871961	medac GmbH\|PPD	Rheumatoid Arthritis (RA)	October 2012	Phase 1
NCT00112034	Biogen	Multiple Sclerosis, Relapsing-Remitting	June 2003	Phase 4
NCT04326894	University of Alexandria	Pain Reduction\|Physical Function Improvement	December 2011	Phase 4
NCT00779142	Wake Forest University\|Wake Forest University Health Sciences	Diabetic Macular Edema	September 2011	Not Applicable
NCT00857389	M.D. Anderson Cancer Center	Stem Cell Transplantation\|Leukemia\|Lymphoma	March 2, 2009	Phase 2
NCT00002581	Scottish Cancer Therapy Network\|National Cancer Institute (NCI)	Breast Cancer	June 1993	Phase 3
NCT00440726	Therapeutic Advances in Childhood Leukemia Consortium	Acute Lymphoblastic Leukemia	August 4, 2006	Phase 1\|Phase 2
NCT05049473	PETHEMA Foundation\|Grupo Español de Linfomas y Transplante Autólogo de Médula Ósea	Mature B-Cell Leukemia Burkitt Type\|Burkitt Lymphoma (BL)\|Unclassifiable Lymphoma Between DCBL and BL	January 2014	Phase 2
NCT03414502	University of Nebraska	Rheumatoid Arthritis	August 2007	Phase 3
NCT01578499	Millennium Pharmaceuticals, Inc.\|Seagen Inc.\|Takeda	Primary Cutaneous Anaplastic Large Cell Lymphoma\|Mycosis Fungoides\|Cutaneous T-Cell Lymphoma	June 11, 2012	Phase 3
NCT04464642	Dr. Mohammad Mamun Khan\|Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh	Rheumatoid Arthritis	July 10, 2019	Phase 4
NCT01432145	University of Oxford	Breast Cancer\|Ovarian Cancer	May 2011	Phase 2
NCT00810199	Hoffmann-La Roche	Rheumatoid Arthritis	March 2009	Phase 3
NCT05602675	Eli Lilly and Company	Healthy	October 31, 2022	Phase 1
NCT03746223	Peking Union Medical College Hospital	Primary Intraocular Lymphoma	November 15, 2018	Phase 2
NCT01645280	Janssen Research & Development, LLC	Arthritis, Rheumatoid	August 2012	Phase 2
NCT01371630	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1\|B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative\|Burkitt-Like Lymphoma With 11q Aberration\|High Grade B-Cell Lymphoma With MYC and BCL2 and+or BCL6 Rearrangements\|High Grade B-Cell Lymphoma, Not Otherwise Specified\|Recurrent B Acute Lymphoblastic Leukemia\|Recurrent Burkitt Lymphoma\|Refractory B Acute Lymphoblastic Leukemia\|Refractory Burkitt Lymphoma	August 26, 2011	Phase 1\|Phase 2
NCT00331097	National Cancer Institute, Naples	Breast Cancer	July 2003	Phase 3
NCT01063062	Hoffmann-La Roche	Rheumatoid Arthritis	February 28, 2010	Phase 3
NCT03813771	University of Leeds\|Samsung Bioepis Co., Ltd.	Rheumatoid Arthritis	March 2019	Phase 4
NCT00084838	Dana-Farber Cancer Institute\|National Cancer Institute (NCI)	Central Nervous System Tumor, Pediatric	February 2003	Phase 2
NCT02196701	AbbVie	Psoriasis	August 5, 2014	Phase 3
NCT00241189	University of California, Los Angeles	Systemic Sclerosis	August 2002	Phase 1\|Phase 2
NCT00760968	Takeda	Arthritis, Rheumatoid	August 2007	Phase 2
NCT00037102	MidAmerica Neuroscience Research Foundation at Rowe Neurology Institute\|Consultants in Neurology\|Biogen	Multiple Sclerosis	July 2001	Phase 4
NCT00439296	Therapeutic Advances in Childhood Leukemia Consortium\|Abbott	Recurrent Pediatric ALL\|Relapsed Pediatric ALL\|Acute Lymphoblastic Leukemia\|Refractory Pediatric ALL	May 22, 2006	Phase 1\|Phase 2
NCT01123265	University of Rochester\|National Psoriasis Foundation	Psoriatic Arthritis	June 2010
NCT00925652	Dana-Farber Cancer Institute\|Brigham and Women´s Hospital\|Beth Israel Deaconess Medical Center\|Translational Breast Cancer Research Consortium\|Genentech, Inc.	Breast Cancer	September 2010	Phase 2
NCT00199069	Johann Wolfgang Goethe University Hospital\|Deutsche Krebshilfe e.V., Bonn (Germany)	Adult Acute Lymphocytic Leukemia	April 1993	Phase 4
NCT02458339	The University of Texas Health Science Center, Houston	Brain Tumor, Recurrent\|Malignant Neoplasm of Fourth Ventricle of Brain	June 15, 2015	Phase 1
NCT01521923	UCB Pharma	Rheumatoid Arthritis	January 2012	Phase 3
NCT02722694	Jiangsu Simcere Pharmaceutical Co., Ltd.\|Bristol-Myers Squibb	Rheumatoid Arthritis (RA)	August 2016	Phase 3
NCT00005086	University of Chicago\|National Cancer Institute (NCI)	Bladder Cancer	August 1999	Phase 2
NCT00005585	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia	April 2000	Phase 3
NCT00199017	Johann Wolfgang Goethe University Hospital	Lymphoma, Lymphoblastic	April 2004	Phase 4
NCT02114229	St. Jude Children´s Research Hospital\|Millennium Pharmaceuticals, Inc.\|Takeda Pharmaceuticals U.S.A., Inc.	Malignant Rhabdoid Tumor\|Atypical Teratoid Rhabdoid Tumor	May 14, 2014	Phase 2
NCT04830878	Stanford University	Proliferative Vitreoretinopathy	April 2021	Phase 1
NCT00968253	M.D. Anderson Cancer Center\|Novartis	Leukemia\|Acute Lymphocytic Leukemia	November 2009	Phase 1\|Phase 2
NCT01230983	Children´s Oncology Group\|National Cancer Institute (NCI)	Cardiac Toxicity\|Leukemia\|Lymphoma	June 1996	Phase 3
NCT01068405	Centre Hospitalier Universitaire de Nice	Polyarthritis	March 2010	Phase 3
NCT00006184	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Multiple Myeloma	February 8, 2001	Phase 2
NCT00317408	European Inter-group Cooperation on Childhood and Adolescent Non Hodgkin Lymphoma\|National Cancer Institute (NCI)	Lymphoma	April 2004	Not Applicable
NCT00195663	AbbVie (prior sponsor, Abbott)\|AbbVie	Early Rheumatoid Arthritis	December 2000	Phase 3
NCT02419755	St. Jude Children´s Research Hospital	Mixed Lineage Acute Leukemia\|Acute Myeloid Leukemia\|Acute Lymphoid Leukemia	April 14, 2015	Phase 2
NCT01535053	GOG Foundation\|National Cancer Institute (NCI)	Choriocarcinoma\|FIGO Stage I Gestational Trophoblastic Tumor\|FIGO Stage II Gestational Trophoblastic Tumor\|FIGO Stage III Gestational Trophoblastic Tumor\|Hydatidiform Mole	June 18, 2012	Phase 3
NCT00038610	M.D. Anderson Cancer Center\|Novartis Pharmaceuticals	Leukemia	March 2001	Phase 2
NCT00003388	Eastern Cooperative Oncology Group\|National Cancer Institute (NCI)	Lymphoma	February 1999	Phase 2
NCT00613457	Associazione Italiana Ematologia Oncologia Pediatrica	Leukemia	September 2000	Phase 3
NCT01709760	Mycenax Biotech Inc.	Rheumatoid Arthritis	November 2012	Phase 3
NCT01001208	Amgen\|Immunex Corporation	Psoriasis	November 2009	Phase 3
NCT03001219	Hoffmann-La Roche	Rheumatoid Arthritis	December 22, 2016	Phase 2
NCT04762498	Horizon Therapeutics Ireland DAC\|Horizon Pharma Ireland, Ltd., Dublin Ireland	Uncontrolled Gout\|Chronic Gout	January 26, 2021	Phase 4
NCT00003019	Children´s Oncology Group\|National Cancer Institute (NCI)\|Children´s Cancer Group	Desmoid Tumor	August 1997	Phase 2
NCT03965728	Bayer	Healthy Volunteers	June 5, 2019	Phase 1
NCT01791153	Hoffmann-La Roche	Giant Cell Arteritis	July 22, 2013	Phase 3
NCT00243750	Charite University, Berlin, Germany	Ankylosing Spondylitis	September 2003	Phase 2
NCT00003838	National Heart, Lung, and Blood Institute (NHLBI)\|National Institutes of Health Clinical Center (CC)	Myeloproliferative Disorders\|Acute Myelogenous Leukemia\|Chronic Myelogenous Leukemia\|Myelodysplastic Syndrome\|Acute Lymphoblastic Leukemia	April 15, 1999	Phase 2
NCT01711359	Eli Lilly and Company	Rheumatoid Arthritis	November 2012	Phase 3
NCT01900431	Sanofi	Uveitis	October 2013	Phase 2
NCT00477412	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Mantle Cell Lymphoma	April 3, 2007	Phase 1\|Phase 2
NCT00365001	Hoffmann-La Roche	Rheumatoid Arthritis		Phase 1
NCT00499889	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Leukemia	February 2003	Phase 2
NCT04934579	Second Affiliated Hospital, School of Medicine, Zhejiang University	Primary Central Nervous System Lymphoma	January 1, 2020	Phase 2
NCT04469829	Universita di Verona	Psoriasis\|Metabolic Syndrome	August 1, 2020	Phase 4
NCT01232920	University of California, San Francisco\|Aravind Eye Hospitals, India	Uveitis	October 2010	Phase 3
NCT00003671	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia	December 1998	Phase 2
NCT00002784	ETOP IBCSG Partners Foundation	Breast Cancer	June 1996	Phase 3
NCT02228772	Massachusetts General Hospital\|Millennium Pharmaceuticals, Inc.	Acute Lymphoblastic Leukemia\|Lymphoblastic Lymphoma\|B-cell Adult Acute Lymphoblastic Leukemia\|T-cell Adult Acute Lymphoblastic Leukemia	December 2014	Phase 1
NCT04154852	University of Leeds\|Abbott	Oligoarthritis	June 2011	Phase 2
NCT00003437	Medical Research Council\|National Cancer Institute (NCI)	Leukemia	January 1997	Phase 3
NCT00136435	Dana-Farber Cancer Institute\|Brigham and Women´s Hospital\|Massachusetts General Hospital\|Queen Elizabeth II Health Sciences Centre	Acute Lymphoblastic Leukemia	June 2002	Phase 2
NCT00002554	Fred Hutchinson Cancer Center	Leukemia	November 1993	Phase 2
NCT01558089	Pfizer	Rheumatoid Arthritis	March 2013
NCT00266227	Genentech, Inc.	Rheumatoid Arthritis	January 2006	Phase 3
NCT00002757	Children´s Oncology Group\|National Cancer Institute (NCI)\|Societe Francaise Oncologie Pediatrique\|Children´s Cancer and Leukaemia Group	Leukemia\|Lymphoma	June 2001	Phase 3
NCT02862574	Gilead Sciences	Rheumatoid Arthritis	December 15, 2016	Phase 2
NCT00036868	European Organisation for Research and Treatment of Cancer - EORTC	Breast Cancer	February 2002	Phase 2
NCT00005940	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)	October 1999	Phase 2
NCT03856216	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|B Acute Lymphoblastic Leukemia\|Lymphocytic Neoplasm\|Lymphoma	October 28, 2019	Phase 2
NCT05623592	University of Bonn	Giant Cell Arteritis	November 2022	Phase 2
NCT00234845	Abbott	Rheumatoid Arthritis	March 2003	Phase 3
NCT00535782	Hoffmann-La Roche	Rheumatoid Arthritis	October 31, 2007	Phase 3
NCT05157971	City of Hope Medical Center\|National Cancer Institute (NCI)	B Acute Lymphoblastic Leukemia\|Ph-Like Acute Lymphoblastic Leukemia	March 17, 2022	Phase 1
NCT05390749	Peking Union Medical College Hospital\|Beijing Tiantan Hospital\|Sanbo Brain Hospital Capital Medical University	Primary Central Nervous System Lymphoma	April 11, 2022	Phase 2
NCT02093026	Hoffmann-La Roche\|Genentech, Inc.	Rheumatoid Arthritis	August 2002	Phase 2
NCT01313858	Merck Sharp & Dohme LLC	Arthritis, Rheumatoid\|Arthritis, Psoriatic\|Spondylitis, Ankylosing	April 2010
NCT05320380	LLS PedAL Initiative, LLC\|Children´s Oncology Group\|ImmunoGen, Inc.\|National Cancer Institute (NCI)	Recurrent Acute Myeloid Leukemia\|Recurrent B Acute Lymphoblastic Leukemia\|Recurrent Mixed Phenotype Acute Leukemia\|Recurrent T Acute Lymphoblastic Leukemia\|Refractory Acute Myeloid Leukemia\|Refractory B Acute Lymphoblastic Leukemia\|Refractory Mixed Phenotype Acute Leukemia\|Refractory T Acute Lymphoblastic Leukemia	December 20, 2022	Phase 1\|Phase 2
NCT00003893	University Hospital Birmingham\|National Cancer Institute (NCI)	Breast Cancer	July 1998	Phase 3
NCT00098774	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Lymphoma	October 2004	Phase 2
NCT00000361	National Institute on Deafness and Other Communication Disorders (NIDCD)	Hearing Loss, Sensorineural	March 1998	Phase 3
NCT02152696	Yale University\|Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)\|Augusta University\|Penn State University\|University of California, San Francisco\|University of North Carolina\|University of Oklahoma\|University of Pennsylvania	Persistent Pregnancy of Unknown Location\|Ectopic Pregnancy	July 25, 2014	Phase 3
NCT04352465	Azidus Brasil\|InCor Heart Institute\|Hospital Santa Marcelina\|Prevent Senior Institute	COVID-19	May 1, 2020	Phase 1\|Phase 2
NCT04942860	Nicolaus Copernicus University	Non-segmental Vitiligo	October 1, 2019	Phase 3
NCT00022737	National Cancer Institute (NCI)	Childhood Acute Lymphoblastic Leukemia in Remission\|Recurrent Childhood Acute Lymphoblastic Leukemia	October 2002	Phase 3
NCT05353829	Region Västerbotten\|Region Gävleborg\|Umeå University\|Uppsala University\|County Council of Norrbotten, Sweden\|Vastra Gotaland Region\|Jämtland County Council, Sweden\|Västernorrland County Council, Sweden\|Dalarna County Council, Sweden\|Karolinska University Hospital\|Danderyd Hospital\|Region Stockholm\|Sormland County Council, Sweden	Rheumatoid Arthritis	April 28, 2022	Phase 4
NCT03962465	University of Virginia\|Pfizer\|Vanderbilt University\|University of Wisconsin, Madison\|Virginia Commonwealth University	B-cell Acute Lymphoblastic Leukemia	July 22, 2022	Phase 1
NCT00033683	Institute of Cancer Research, United Kingdom\|National Cancer Institute (NCI)	Breast Cancer	February 2001	Phase 2
NCT00400946	Dana-Farber Cancer Institute\|National Cancer Institute (NCI)	Drug+Agent Toxicity by Tissue+Organ\|Leukemia	April 2005	Phase 3
NCT00022516	ETOP IBCSG Partners Foundation	Breast Cancer	November 2000	Phase 3
NCT00012051	Commissie Voor Klinisch Toegepast Onderzoek\|National Cancer Institute (NCI)	Lymphoma	September 2000	Phase 3
NCT00896168	Xian-Janssen Pharmaceutical Ltd.	Arthritis, Rheumatoid	June 2007	Phase 4
NCT04268394	Celgene	Healthy Volunteer	March 13, 2020	Phase 1
NCT00298272	Biogen\|Hoffmann-La Roche\|Genentech, Inc.	Rheumatoid Arthritis	May 2006	Phase 2
NCT00213564	University Hospital, Rouen	Rheumatoid Arthritis	April 2003
NCT02518750	St. Jude Children´s Research Hospital\|Novartis Pharmaceuticals\|Spectrum Pharmaceuticals, Inc	Acute Lymphoblastic Leukemia\|Lymphoma, Non-Hodgkin´s\|Leukemia, T-Cell\|Leukemia, B-Cell	November 23, 2016	Phase 2
NCT00049569	National Cancer Institute (NCI)	L1 Childhood Acute Lymphoblastic Leukemia\|L2 Childhood Acute Lymphoblastic Leukemia\|Non-T, Non-B Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood Acute Lymphoblastic Leukemia\|T-cell Childhood Acute Lymphoblastic Leukemia	January 2003	Not Applicable
NCT00448201	UNC Lineberger Comprehensive Cancer Center\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes	January 7, 2011	Phase 2
NCT02001987	Hoffmann-La Roche	Rheumatoid Arthritis	January 2014	Phase 3
NCT00296010	ETOP IBCSG Partners Foundation	Breast Cancer	August 2005	Phase 3
NCT00653068	Children´s Oncology Group\|National Cancer Institute (NCI)	Childhood Atypical Teratoid+Rhabdoid Tumor	December 8, 2008	Phase 3
NCT01015547	Helsinki University Central Hospital\|Foundation for Paediatric Research, Finland\|Päivikki and Sakari Sohlberg Foundation, Finland\|Rheumatism Foundation Hospital\|Scandinavian Rheumatology Research Foundation\|Paijat-Hame Hospital District	Juvenile Idiopathic Arthritis	May 2003	Phase 3
NCT00406419	Genentech, Inc.\|Roche Pharma AG	Rheumatoid Arthritis	December 27, 2006	Phase 3
NCT00485589	Genentech, Inc.\|Roche Pharma AG	Rheumatoid Arthritis	June 11, 2007	Phase 3
NCT03864419	Fred Hutchinson Cancer Center	Burkitt Lymphoma\|KSHV-associated Multicentric Castleman Disease\|Diffuse Large B-Cell Lymphoma	October 24, 2019	Phase 1
NCT01319981	M.D. Anderson Cancer Center\|Spectrum Pharmaceuticals, Inc	Leukemia	March 5, 2013	Phase 2
NCT01768572	Sanofi\|Regeneron Pharmaceuticals	Rheumatoid Arthritis	March 2013	Phase 3
NCT00334672	Children´s Cancer and Leukaemia Group\|National Cancer Institute (NCI)	Nonneoplastic Condition	March 2006	Phase 3
NCT00783510	AbbVie	Juvenile Idiopathic Arthritis\|JIA	July 11, 2008
NCT01554696	Astellas Pharma Inc	Arthritis, Rheumatoid	July 6, 2012	Phase 2
NCT01393405	University of North Carolina, Chapel Hill\|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	Ulcerative Colitis	February 2012	Phase 2
NCT00194792	University of Washington\|National Cancer Institute (NCI)	Estrogen Receptor-positive Breast Cancer\|HER2-negative Breast Cancer\|Progesterone Receptor-positive Breast Cancer\|Stage I Breast Cancer\|Stage II Breast Cancer\|Stage IIIA Breast Cancer	August 2005	Phase 2
NCT01527149	Roswell Park Cancer Institute\|National Comprehensive Cancer Network	Stage I Mantle Cell Lymphoma\|Stage II Contiguous Mantle Cell Lymphoma\|Stage II Non-Contiguous Mantle Cell Lymphoma\|Stage III Mantle Cell Lymphoma\|Stage IV Mantle Cell Lymphoma	December 6, 2011	Phase 2
NCT00006056	Fairview University Medical Center\|Office of Rare Diseases (ORD)	Chediak-Higashi Syndrome\|Graft Versus Host Disease\|X-Linked Lymphoproliferative Syndrome\|Familial Erythrophagocytic Lymphohistiocytosis\|Hemophagocytic Lymphohistiocytosis\|Virus-Associated Hemophagocytic Syndrome	March 2000	Not Applicable
NCT01490723	M.D. Anderson Cancer Center\|Spectrum Pharmaceuticals, Inc	Leukemia\|Lymphoma	January 2013	Phase 2
NCT02634801	Eli Lilly and Company	Plaque Psoriasis	January 20, 2016	Phase 3
NCT04108468	The Leeds Teaching Hospitals NHS Trust\|Janssen Pharmaceutica N.V., Belgium	Psoriatic Arthritis	October 27, 2015	Phase 3
NCT00919503	Fred Hutchinson Cancer Center\|medac GmbH\|National Cancer Institute (NCI)\|National Heart, Lung, and Blood Institute (NHLBI)	Non-Neoplastic Hematologic and Lymphocytic Disorder	July 31, 2009	Phase 2
NCT00004228	Children´s Oncology Group\|National Cancer Institute (NCI)	Lymphoma	June 2000	Phase 3
NCT00636909	Beth Israel Deaconess Medical Center\|Amgen	AML\|ALL\|CML Chronic Phase, Accelerated Phase, or Blast Crisis\|CLL\|MDS\|RELAPSED NON-HODGKIN´S OR HODGKIN´S LYMPHOMA\|APLASTIC ANEMIA\|MULTIPLE MYELOMA\|MYELOPROLIFERATIVE DISORDER (P Vera, CMML, ET)	July 1999	Phase 2
NCT00002696	Grupo Oncologico Cooperativo del Sur\|National Cancer Institute (NCI)	Breast Cancer	October 1995	Phase 3
NCT03332719	Gema Biotech S.A.\|QUID Quality in Drugs and Devices Latin American Consulting SRL	Rheumatoid Arthritis	February 2016	Phase 3
NCT04758689	Cairo University	Rheumatoid Arthritis	November 20, 2020	Not Applicable
NCT00039377	National Cancer Institute (NCI)	Adult Acute Lymphoblastic Leukemia in Remission	April 2002	Phase 2
NCT01414257	Pfizer	Arthritis\|Rheumatoid\|High Dose	May 2011
NCT00808639	Dana-Farber Cancer Institute\|Beth Israel Deaconess Medical Center\|Brigham and Women´s Hospital\|Amgen	Bladder Cancer\|Muscle-invasive Bladder Cancer	December 2008	Phase 2
NCT04747912	University of Chicago	Lymphoblastic Leukemia\|Acute Lymphoblastic Leukemia\|ph&addition; Acute Lymphoblastic Leukemia	March 2, 2021	Phase 2
NCT05575297	Seoul National University Hospital	Drug Interaction	December 20, 2021	Phase 1
NCT05549284	Affiliated Hospital to Academy of Military Medical Sciences	Primary Central Nervous System Lymphoma	June 1, 2022	Phase 2
NCT02020161	PETHEMA Foundation	APL	June 2012	Phase 4
NCT02323659	Polish Lymphoma Research Group	Lymphoma, T-Cell, Cutaneous\|Mycosis Fungoides	June 1, 2014	Phase 4
NCT00866749	M.D. Anderson Cancer Center	Lymphoblastic Leukemia\|Lymphoblastic Lymphoma	September 12, 2006	Phase 2
NCT02412670	ECOG-ACRIN Cancer Research Group\|National Cancer Institute (NCI)\|Eastern Cooperative Oncology Group	High Grade Upper Tract Urothelial Carcinoma	April 1, 2015	Phase 2
NCT01358201	PETHEMA Foundation	Acute Lymphoblastic Leukemia	May 2010	Phase 4
NCT00264537	Centocor, Inc.\|Schering-Plough	Rheumatoid Arthritis	December 2005	Phase 3
NCT00003549	Southwest Oncology Group\|National Cancer Institute (NCI)	Neuroendocrine Carcinoma of the Skin	October 1998	Phase 2
NCT01654575	University of Alexandria	Osteoarthritis	July 2011	Not Applicable
NCT02776605	PETHEMA Foundation	ALL	June 2016	Phase 2
NCT00002812	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia	September 1996	Phase 3
NCT00275106	Children´s Cancer and Leukaemia Group\|European Inter-group Cooperation on Childhood and Adolescent Non Hodgkin Lymphoma\|National Cancer Institute (NCI)	Lymphoma	September 2004	Phase 3
NCT01786018	Azienda Ospedaliera San Giovanni Battista	B-cell Lymphoma Refractory	February 2013	Phase 2
NCT01230827	Janssen Research & Development, LLC\|Schering-Plough	Juvenile Idiopathic Arthritis	December 2010	Phase 3
NCT03402087	Bristol-Myers Squibb	Lupus\|Psoriatic Arthritis	January 8, 2018	Phase 1
NCT03959085	Children´s Oncology Group\|National Cancer Institute (NCI)	B Acute Lymphoblastic Leukemia\|B Lymphoblastic Lymphoma\|Central Nervous System Leukemia\|Mixed Phenotype Acute Leukemia\|Testicular Leukemia	October 28, 2019	Phase 3
NCT00005603	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia	March 2000	Phase 3
NCT00764907	University Hospital, Motol\|National Cancer Institute (NCI)	Leukemia	November 2002	Phase 3
NCT00397501	OHSU Knight Cancer Institute\|National Cancer Institute (NCI)	Brain and Central Nervous System Tumors\|Breast Cancer\|Cognitive+Functional Effects\|Drug+Agent Toxicity by Tissue+Organ\|Psychosocial Effects of Cancer and Its Treatment	October 2013	Phase 1\|Phase 2
NCT04009525	First Affiliated Hospital of Guangxi Medical University\|Peking University People´s Hospital\|Ruijin Hospital\|The 923th Hospital of People´s Liberation Army\|Fourth Affiliated Hospital of Guangxi Medical University\|Liuzhou General Hospital\|Hainan General Hospital\|The Affiliated Hospital Of Guizhou Medical University\|The First People´s Hospital of Yunnan	Thalassemia Major	June 1, 2019	Phase 4
NCT01769209	Stanford University\|National Cancer Institute (NCI)	B-cell Adult Acute Lymphoblastic Leukemia (ALL)\|Ph-positive Adult Acute Lymphoblastic Leukemia (ALL)\|Recurrent Adult Acute Lymphoblastic Leukemia (ALL)\|T-cell Adult Acute Lymphoblastic Leukemia (ALL)	March 2013	Phase 2
NCT00215046	Boston Children´s Hospital\|Dana-Farber Cancer Institute	Intraluminal Pulmonary Vein Stenosis	March 2000	Phase 2
NCT00003311	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Lymphoma	May 20, 1998	Phase 2
NCT00005854	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes	December 1999	Phase 2
NCT00578305	Hoffmann-La Roche	Rheumatoid Arthritis	November 2007	Phase 3
NCT02389400	Peking Union Medical College Hospital	Langerhans Cell Histiocytosis	January 2014	Phase 2
NCT03449758	Sanofi\|Regeneron Pharmaceuticals	Rheumatoid Arthritis	March 5, 2018	Phase 4
NCT01855789	Hoffmann-La Roche	Rheumatoid Arthritis	November 7, 2013	Phase 3
NCT01500278	UCB Pharma SA\|Parexel\|UCB Pharma	Rheumatoid Arthritis	December 2011	Phase 4
NCT00343369	Universitätsklinikum Hamburg-Eppendorf\|National Cancer Institute (NCI)	Leukemia	January 2003	Not Applicable
NCT00901550	Chinese University of Hong Kong	Rheumatoid Arthritis	November 2008	Not Applicable
NCT00496665	Dana-Farber Cancer Institute\|AstraZeneca\|Massachusetts General Hospital\|Brigham and Women´s Hospital	Metastatic Breast Cancer	July 2007	Phase 1
NCT00003060	Louisiana State University Health Sciences Center Shreveport	Melanoma (Skin)	March 1995	Phase 1
NCT00441961	Radboud University Medical Center	Fasciitis	October 2006	Not Applicable
NCT05429450	Cairo University	Thyroid Associated Orbitopathy	July 1, 2020	Phase 2
NCT00550992	Dutch Childhood Oncology Group\|BFM Germany\|CORS Monza Italy\|Associazione Italiana Ematologia Oncologia Pediatrica\|Australian and New Zealand Children´s Oncology Group\|BFM Austria\|CLCG France Belgium Portugal\|COALL Germany\|CPH, Czech republic\|DFCI consortium USA\|FRALLE France\|Hong Kong\|MD Anderson USA\|NOPHO Scandinavian countries\|PINDA, Chile\|PPLLSG Poland\|Seattle USA\|SJCRH USA\|UKCCSG United Kingdom	Leukemia	January 2006	Not Applicable
NCT04546399	National Cancer Institute (NCI)	Down Syndrome\|Recurrent B Acute Lymphoblastic Leukemia	December 4, 2020	Phase 2
NCT00028756	European Organisation for Research and Treatment of Cancer - EORTC\|National Cancer Institute (NCI)\|Groupe D´Etude des Tumeurs Uro-Genitales\|Institute of Cancer Research, United Kingdom\|NCIC Clinical Trials Group\|Arbeitsgemeinschaft Urologische Onkologie	Stage III Bladder Cancer\|Stage IV Bladder Cancer\|Transitional Cell Carcinoma of the Bladder	October 2001	Phase 3
NCT00002744	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia	May 1996	Phase 3
NCT00392834	AIDS Malignancy Consortium\|National Cancer Institute (NCI)\|The Emmes Company, LLC	Lymphoma	September 2006	Phase 2
NCT01176981	The Hospital for Sick Children	Osteosarcoma	October 2010	Phase 3
NCT03813199	Abivax S.A.	Rheumatoid Arthritis	July 4, 2019	Phase 2
NCT00642460	Hoffmann-La Roche	Juvenile Idiopathic Arthritis	May 2008	Phase 3
NCT02187055	Pfizer	Rhematoid Arthritis	August 2014	Phase 4
NCT00082797	Eastern Cooperative Oncology Group\|National Cancer Institute (NCI)	Brain and Central Nervous System Tumors	February 2005	Phase 2
NCT05008887	Assiut University	Vitiligo	September 2022	Phase 4
NCT02413047	Indiana University	Inflammatory Bowel Disease\|Ulcerative Colitis\|Crohn´s Disease	May 2015	Not Applicable
NCT00335140	Eastern Cooperative Oncology Group	Lymphoma	December 2006	Phase 2
NCT00049634	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Leukemia\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases	January 2002	Phase 1\|Phase 2
NCT02017964	Children´s Oncology Group\|National Cancer Institute (NCI)	Desmoplastic+Nodular Medulloblastoma\|Medulloblastoma\|Medulloblastoma With Extensive Nodularity\|Nevoid Basal Cell Carcinoma Syndrome\|Untreated Childhood Medulloblastoma	April 22, 2014	Phase 2
NCT05300009	Assiut University	Warts	June 15, 2022	Not Applicable
NCT00210379	International Extranodal Lymphoma Study Group (IELSG)	Lymphoma, B Cell	November 2000	Phase 2
NCT02203526	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Primary Central Nervous System Lymphoma	August 14, 2014	Phase 1
NCT02897011	Seoul National University Hospital	Rheumatoid Arthritis\|Influenza\|Methotrexate	September 2016	Not Applicable
NCT00121134	Harold J. Burstein, MD, PhD\|Genentech, Inc.\|Beth Israel Deaconess Medical Center\|Indiana University School of Medicine\|University of California, San Francisco\|University of North Carolina\|Dana-Farber Cancer Institute	Breast Cancer	June 2005	Not Applicable
NCT02339350	The Korean Society of Pediatric Hematology Oncology	Acute Lymphoblastic Leukemia\|Child	January 2015	Phase 2
NCT00443430	Seattle Children´s Hospital\|National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)\|Amgen	Juvenile Chronic Polyarthritis\|Juvenile Idiopathic Arthritis\|Juvenile Rheumatoid Arthritis	May 2007	Phase 4
NCT00187122	St. Jude Children´s Research Hospital	Lymphoblastic Lymphoma	March 1993	Not Applicable
NCT00382109	Children´s Oncology Group\|National Cancer Institute (NCI)	B-cell Childhood Acute Lymphoblastic Leukemia\|Childhood Acute Lymphoblastic Leukemia in Remission\|Graft Versus Host Disease\|L1 Childhood Acute Lymphoblastic Leukemia\|L2 Childhood Acute Lymphoblastic Leukemia\|T-cell Childhood Acute Lymphoblastic Leukemia	March 2007	Phase 3
NCT00002557	National Cancer Institute (NCI)	Lymphoma	June 1993	Phase 2
NCT00057954	Eastern Cooperative Oncology Group\|National Cancer Institute (NCI)	Lymphoma	June 2005	Phase 2
NCT00470522	University Health Network, Toronto\|McGill University Health Centre+Research Institute of the McGill University Health Centre	Systemic Lupus Erythematosus	June 1995	Phase 3
NCT00018954	National Institutes of Health Clinical Center (CC)\|National Cancer Institute (NCI)	Leukemia\|Lymphoma	October 1992	Phase 2
NCT04168619	The University of Hong Kong	Psoriasis\|Liver Fibrosis	June 10, 2019
NCT04691505	Brigham and Women´s Hospital\|National Institute on Aging (NIA)\|Rutgers University\|Johns Hopkins University	Rheumatoid Arthritis	December 23, 2020
NCT00002785	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia	July 1996	Phase 2
NCT00967057	Children´s Cancer and Leukaemia Group\|National Cancer Institute (NCI)	Leukemia	October 2002	Phase 3
NCT00392886	Children´s Hospital Los Angeles\|National Cancer Institute (NCI)	Brain and Central Nervous System Tumors	March 2004	Phase 3
NCT02419469	M.D. Anderson Cancer Center\|Jazz Pharmaceuticals	Leukemia\|Precursor-B Acute Lymphoblastic Leukemia\|Lymphoblastic Lymphoma\|Lymphoma	November 13, 2015	Phase 2
NCT00470223	UNICANCER\|Novartis\|Chugai Pharmaceutical\|National Cancer Institute, France\|SFCE\|Ligue contre le cancer, France	Sarcoma	March 2007	Phase 3
NCT02553460	St. Jude Children´s Research Hospital\|Gateway for Cancer Research\|Baylor College of Medicine	Acute Lymphoblastic Leukemia	January 29, 2016	Phase 1\|Phase 2
NCT00193011	SCRI Development Innovations, LLC\|Aventis Pharmaceuticals	Breast Cancer	March 2002	Phase 3
NCT03150693	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	B Acute Lymphoblastic Leukemia	June 1, 2017	Phase 3
NCT04157010	University of Leeds\|Hoffmann-La Roche	Rheumatoid Arthritis	May 2013	Phase 4
NCT00932113	Tufts Medical Center	Psoriasis	June 2009	Phase 4
NCT01927484	University of Alexandria	Reduction in Pain\|Reduction of Inflammation\|Improvement in Function	March 7, 2020	Not Applicable
NCT01870128	All India Institute of Medical Sciences, New Delhi	Rheumatoid Arthritis	August 2009	Phase 3
NCT00487825	Novartis	Rheumatoid Arthritis	March 2007	Phase 2
NCT00003012	Scottish Cancer Therapy Network\|National Cancer Institute (NCI)	Breast Cancer	October 1996	Phase 3
NCT00003577	University Hospital Birmingham\|National Cancer Institute (NCI)	Breast Cancer	March 1996	Phase 3
NCT00003215	Swiss Group for Clinical Cancer Research	Lymphoma	April 1997	Phase 3
NCT00792948	National Cancer Institute (NCI)	Acute Lymphoblastic Leukemia\|Adult B Acute Lymphoblastic Leukemia\|Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1\|Adult L1 Acute Lymphoblastic Leukemia\|Adult L2 Acute Lymphoblastic Leukemia\|Adult T Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Lymphoblastic Leukemia	September 1, 2009	Phase 2
NCT00290433	M.D. Anderson Cancer Center\|Ortho Biotech, Inc.	Lymphoma	September 2003	Phase 2
NCT01009242	UCB Pharma	Arthritis\|Rheumatoid Arthritis	October 2009	Phase 1\|Phase 2
NCT04177173	King Edward Medical University	Arthritis, Rheumatoid	September 1, 2017	Phase 4
NCT00296023	University of California, San Francisco\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes	January 1999	Not Applicable
NCT00124111	Amgen	Breast Cancer		Phase 2
NCT00003680	Scottish Cancer Therapy Network\|National Cancer Institute (NCI)	Breast Cancer	November 1998	Phase 3
NCT00928200	Therapeutic Advances in Childhood Leukemia Consortium	Relapsed Acute Lymphoblastic Leukemia\|Allergy to PEG e.Coli Asparaginase\|Allergy to Native e.Coli Asparaginase	April 13, 2009	Phase 1
NCT00775632	University Health Network, Toronto\|Bayer	Graft Versus Host Disease\|Bone Marrow Transplantation	October 2008	Phase 2
NCT00458848	Gruppo Italiano Malattie EMatologiche dell´Adulto	Leukemia	October 2004	Phase 2
NCT03569995	Won Seog Kim\|Celltrion\|Samsung Medical Center	Primary CNS Lymphoma	November 30, 2018	Phase 2
NCT01228331	Universitätsklinikum Hamburg-Eppendorf	Leukemia	October 2010	Phase 2\|Phase 3
NCT00346359	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Graft Versus Host Disease\|Leukemia\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases	March 2006	Phase 2
NCT01519791	UCB Pharma SA\|UCB Pharma	Rheumatoid Arthritis	January 2012	Phase 3
NCT00516750	Kyoto University\|National Cancer Institute (NCI)	Bladder Cancer	July 2007	Phase 2
NCT00616122	University of California, San Francisco\|National Cancer Institute (NCI)	Breast Cancer	March 1, 2006	Phase 1\|Phase 2
NCT00003910	Eastern Cooperative Oncology Group\|National Cancer Institute (NCI)	Leukemia	July 16, 1999	Phase 2
NCT02275299	Jiangsu Simcere Pharmaceutical Co., Ltd.	Rheumatoid Arthritis	September 2013	Phase 4
NCT03277924	Grupo Espanol de Investigacion en Sarcomas	Soft Tissue Sarcoma\|Bone Sarcoma	May 31, 2017	Phase 1\|Phase 2
NCT00253552	OHSU Knight Cancer Institute\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Graft Versus Host Disease\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases\|Sarcoma	May 2004	Not Applicable
NCT00002798	National Cancer Institute (NCI)	Childhood Acute Erythroleukemia (M6)\|Childhood Acute Megakaryocytic Leukemia (M7)\|Childhood Acute Monoblastic Leukemia (M5a)\|Childhood Acute Monocytic Leukemia (M5b)\|Childhood Acute Myeloblastic Leukemia With Maturation (M2)\|Childhood Acute Myeloblastic Leukemia Without Maturation (M1)\|Childhood Acute Myelomonocytic Leukemia (M4)\|Childhood Myelodysplastic Syndromes\|Chronic Myelomonocytic Leukemia\|de Novo Myelodysplastic Syndromes\|Refractory Anemia\|Refractory Anemia With Excess Blasts\|Refractory Anemia With Excess Blasts in Transformation\|Refractory Anemia With Ringed Sideroblasts\|Secondary Myelodysplastic Syndromes\|Untreated Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies	August 1996	Phase 3
NCT05032183	M.D. Anderson Cancer Center	Recurrent Adult Lymphoblastic Lymphoma\|Recurrent B Acute Lymphoblastic Leukemia\|Recurrent T Acute Lymphoblastic Leukemia\|Refractory B Acute Lymphoblastic Leukemia\|Refractory Lymphoblastic Lymphoma\|Refractory T Acute Lymphoblastic Leukemia	February 17, 2022	Phase 1\|Phase 2
NCT00074178	OHSU Knight Cancer Institute\|National Cancer Institute (NCI)	Lymphoma	January 2000	Phase 2
NCT00023998	National Cancer Institute (NCI)	Metastatic Osteosarcoma	July 2001	Phase 2
NCT01848457	Children´s Hospital of Philadelphia\|Gateway for Cancer Research	Osteosarcoma\|Nephrotoxicity\|Ototoxicity	April 2013	Phase 2
NCT00523692	University Hospital Birmingham\|Wyeth is now a wholly owned subsidiary of Pfizer	Rheumatoid Arthritis	September 2007	Phase 4
NCT00476996	Genentech, Inc.\|Roche Pharma AG	Rheumatoid Arthritis	May 15, 2007	Phase 3
NCT00133991	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins\|National Cancer Institute (NCI)	Leukemia\|Lymphoma	July 2005	Phase 2
NCT05408208	Sohag University	Localized Psoriasis	May 21, 2022	Not Applicable
NCT03964090	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Central Nervous System Lymphoma\|Secondary Central Nervous System Lymphoma	June 27, 2019	Phase 2
NCT04129710	Second Affiliated Hospital, School of Medicine, Zhejiang University\|Ruijin Hospital\|The First Affiliated Hospital of Nanchang University\|Fujian Medical University Union Hospital\|RenJi Hospital\|Shanghai Tong Ren Hospital\|Shandong Provincial Hospital\|Cancer Hospital of Guangxi Medical University\|Sir Run Run Shaw Hospital\|Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University\|Ningbo Medical Center Lihuili Hospital\|Yinzhou Hospital Affiliated to Medical School of Ningbo University\|Zhejiang University	Recurrent+RefractoryPrimary Central Nervous System Lymphoma (PCNSL)	January 1, 2020	Phase 2
NCT00176462	Rutgers, The State University of New Jersey\|National Cancer Institute (NCI)	Acute Lymphocytic Leukemia	February 2001	Phase 2
NCT02076997	Baylor College of Medicine\|Texas Children´s Cancer Center	Cancer	January 1, 2014	Not Applicable
NCT00981799	Therapeutic Advances in Childhood Leukemia Consortium\|GlaxoSmithKline\|Novartis	Relapsed T-Cell Acute Lymphoblastic Leukemia\|Relapsed T-Cell Lymphoblastic Lymphoma	June 2010	Phase 1\|Phase 2
NCT00126191	Dana-Farber Cancer Institute\|Beth Israel Deaconess Medical Center\|Brigham and Women´s Hospital	Burkitt Lymphoma\|Non-Hodgkins Lymphoma\|Atypical Burkitt Lymphoma	July 2005	Phase 2
NCT00632827	University of California, San Francisco\|Eisai Inc.\|Washington University School of Medicine	Peripheral T-Cell Lymphoma	July 1, 2008	Phase 2
NCT00014274	European Organisation for Research and Treatment of Cancer - EORTC	Bladder Cancer\|Transitional Cell Cancer of the Renal Pelvis and Ureter\|Urethral Cancer	January 2001	Phase 2\|Phase 3
NCT04293562	Children´s Oncology Group\|National Cancer Institute (NCI)	Acute Myeloid Leukemia	July 20, 2020	Phase 3
NCT05535166	St. Jude Children´s Research Hospital	Medulloblastoma	November 2022	Phase 2
NCT00579644	University of Nebraska	Rheumatoid Arthritis	January 2001	Phase 3
NCT00973752	Massachusetts General Hospital\|Dana-Farber Cancer Institute\|Beth Israel Deaconess Medical Center\|Enzon Pharmaceuticals, Inc.\|Genzyme, a Sanofi Company	Acute Lymphoblastic Leukemia	August 2009	Phase 2
NCT00002552	Barbara Ann Karmanos Cancer Institute\|National Cancer Institute (NCI)	Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm	October 1993	Phase 2
NCT03589326	Takeda	Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph&addition;ALL)	August 10, 2018	Phase 3
NCT04077957	Nanfang Hospital of Southern Medical University	Ankylosing Spondylitis\|Spondyloarthritis	October 7, 2019	Phase 4
NCT02252042	Merck Sharp & Dohme LLC	Head and Neck Squamous Cell Cancer	November 17, 2014	Phase 3
NCT00934648	Hoffmann-La Roche	Rheumatoid Arthritis	October 2007	Phase 4
NCT02393378	Takeda	Rheumatoid Arthritis	April 8, 2015	Phase 2
NCT01390441	Merck Sharp & Dohme LLC	Rheumatoid Arthritis	July 2011	Phase 1
NCT00002789	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Leukemia	May 1996	Phase 3
NCT00002618	Children´s Oncology Group\|National Cancer Institute (NCI)	Lymphoma	December 1994	Phase 3
NCT00974792	Cancer Research UK\|National Cancer Institute (NCI)	Lymphoma	January 2006	Phase 2
NCT03424629	Tianjin Ever Union Biotechnology Co., Ltd.	Moderate and Severe Plaque Psoriasis	June 1, 2018	Phase 1
NCT00024050	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Leukemia\|Myelodysplastic Syndromes	February 2001	Phase 2
NCT00439556	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	CD20 Positive\|Hematopoietic and Lymphoid Cell Neoplasm\|Lymphocytic Neoplasm\|Lymphoma	February 13, 2007	Phase 2
NCT05579769	St. Jude Children´s Research Hospital	Hematologic Malignancy\|Myeloid Malignancy	November 4, 2022	Phase 2
NCT00282308	Genentech, Inc.	Rheumatoid Arthritis	January 23, 2006	Phase 2
NCT03813147	National Cancer Institute (NCI)\|Children´s Oncology Group	Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome\|Recurrent Acute Myeloid Leukemia\|Recurrent Myelodysplastic Syndrome\|Refractory Acute Myeloid Leukemia\|Refractory Myelodysplastic Syndrome	May 1, 2019	Phase 1
NCT02022358	University College, London\|Richard Scowcroft Foundation	Osteosarcoma\|Spindle Cell Sarcoma of Bone	July 2007	Phase 2
NCT00002578	Roswell Park Cancer Institute\|National Cancer Institute (NCI)	Lymphoma	August 1994	Phase 2
NCT00134030	Children´s Oncology Group\|National Cancer Institute (NCI)\|University College London Hospitals	Localized Osteosarcoma\|Metastatic Osteosarcoma	November 14, 2005	Phase 3
NCT03518112	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Philadelphia Chromosome Negative\|Recurrent B Acute Lymphoblastic Leukemia\|Refractory B Acute Lymphoblastic Leukemia	April 18, 2018	Phase 2
NCT00028600	Alliance for Clinical Trials in Oncology\|National Cancer Institute (NCI)	Multiple Myeloma\|Plasma Cell Neoplasm	November 2001	Phase 2
NCT02885181	Gilead Sciences	Rheumatoid Arthritis	September 21, 2016	Phase 2
NCT05508815	Beijing University of Chinese Medicine	Arthritis, Rheumatoid	September 1, 2022	Early Phase 1
NCT01884623	Gustave Roussy, Cancer Campus, Grand Paris\|National Cancer Institute, France\|Ligue contre le cancer, France\|Merck Serono International SA	Head Neck Cancer Squamous Cell Recurrent	November 6, 2013	Phase 3
NCT03408756	Postgraduate Institute of Medical Education and Research	Psoriasis Vulgaris	April 1, 2018	Phase 4
NCT04383743	University of Washington\|Merck Sharp & Dohme LLC	Stage II Bladder Cancer AJCC v8\|Stage IIIA Bladder Cancer AJCC v8\|Muscle Invasive Bladder Carcinoma	November 24, 2020	Phase 2
NCT02373579	Nancy Samir Elbarbary\|Ain Shams University	Acute Lymphoblastic Leukemia	June 2012	Phase 2
NCT00002665	Southwest Oncology Group\|National Cancer Institute (NCI)	Leukemia\|Neutropenia\|Thrombocytopenia	July 1995	Phase 2
NCT00544115	City of Hope Medical Center\|National Cancer Institute (NCI)	Chronic Myeloproliferative Disorders\|Graft Versus Host Disease\|Leukemia\|Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases\|Precancerous+Nonmalignant Condition	October 16, 2001	Phase 2
NCT03058900	Odense University Hospital\|Region of Southern Denmark\|University of Southern Denmark\|The Danish Rheumatism Association\|Odense Patient Data Explorative Network\|The Psoriasis Association, Denmark\|Manufacturer Vilhelm Pedersen Foundation\|The Danish Regions (Medicinpuljen)	Psoriatic Arthritis	May 16, 2017	Not Applicable
NCT05398224	Peking University	Secondary Central Nervous System Lymphoma	February 26, 2021	Phase 2
NCT00299130	Genentech, Inc.\|Hoffmann-La Roche	Rheumatoid Arthritis	October 2005	Phase 3
NCT03244462	Bayer	Inflammation	August 18, 2017	Phase 1
NCT01162421	AbbVie (prior sponsor, Abbott)\|Mount Sinai Hospital, Canada\|AbbVie	Rheumatoid Arthritis	September 2010	Phase 4
NCT00853008	PETHEMA Foundation	Acute Lymphoblastic Leukemia	January 2003	Phase 4
NCT04514393	Huiqiang Huang\|Guangdong 999 Brain Hospital\|Nanfang Hospital of Southern Medical University\|Xian-Janssen Pharmaceutical Ltd.\|Sun Yat-sen University	Primary Central Nervous System Lymphoma\|PCNSL\|Non Hodgkin Lymphoma	October 10, 2020	Phase 2
NCT01789255	National Cancer Institute (NCI)	Accelerated Phase Chronic Myelogenous Leukemia\|Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|Adult Grade III Lymphomatoid Granulomatosis\|B-cell Chronic Lymphocytic Leukemia\|Chronic Myelogenous Leukemia, BCR-ABL1 Positive\|Chronic Myelomonocytic Leukemia\|Chronic Phase Chronic Myelogenous Leukemia\|Contiguous Stage II Adult Burkitt Lymphoma\|Contiguous Stage II Adult Diffuse Large Cell Lymphoma\|Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma\|Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma\|Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma\|Contiguous Stage II Adult Lymphoblastic Lymphoma\|Contiguous Stage II Grade 1 Follicular Lymphoma\|Contiguous Stage II Grade 2 Follicular Lymphoma\|Contiguous Stage II Grade 3 Follicular Lymphoma\|Contiguous Stage II Mantle Cell Lymphoma\|Contiguous Stage II Marginal Zone Lymphoma\|Contiguous Stage II Small Lymphocytic Lymphoma\|Cutaneous B-cell Non-Hodgkin Lymphoma\|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue\|Graft Versus Host Disease\|Intraocular Lymphoma\|Myelodysplastic Syndrome With Isolated Del(5q)\|Myelodysplastic+Myeloproliferative Neoplasm, Unclassifiable\|Nodal Marginal Zone B-cell Lymphoma\|Noncontiguous Stage II Adult Burkitt Lymphoma\|Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma\|Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma\|Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma\|Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma\|Noncontiguous Stage II Adult Lymphoblastic Lymphoma\|Noncontiguous Stage II Grade 1 Follicular Lymphoma\|Noncontiguous Stage II Grade 2 Follicular Lymphoma\|Noncontiguous Stage II Grade 3 Follicular Lymphoma\|Noncontiguous Stage II Mantle Cell Lymphoma\|Noncontiguous Stage II Marginal Zone Lymphoma\|Noncontiguous Stage II Small Lymphocytic Lymphoma\|Post-transplant Lymphoproliferative Disorder\|Primary Central Nervous System Hodgkin Lymphoma\|Primary Central Nervous System Non-Hodgkin Lymphoma\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Adult Burkitt Lymphoma\|Recurrent Adult Diffuse Large Cell Lymphoma\|Recurrent Adult Diffuse Mixed Cell Lymphoma\|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma\|Recurrent Adult Grade III Lymphomatoid Granulomatosis\|Recurrent Adult Hodgkin Lymphoma\|Recurrent Adult Immunoblastic Large Cell Lymphoma\|Recurrent Adult Lymphoblastic Lymphoma\|Recurrent Grade 1 Follicular Lymphoma\|Recurrent Grade 2 Follicular Lymphoma\|Recurrent Grade 3 Follicular Lymphoma\|Recurrent Mantle Cell Lymphoma\|Recurrent Marginal Zone Lymphoma\|Recurrent Small Lymphocytic Lymphoma\|Refractory Anemia\|Refractory Anemia With Excess Blasts\|Refractory Anemia With Ringed Sideroblasts\|Refractory Chronic Lymphocytic Leukemia\|Refractory Cytopenia With Multilineage Dysplasia\|Refractory Hairy Cell Leukemia\|Relapsing Chronic Myelogenous Leukemia\|Secondary Central Nervous System Hodgkin Lymphoma\|Secondary Central Nervous System Non-Hodgkin Lymphoma\|Small Intestine Lymphoma\|Splenic Marginal Zone Lymphoma\|Stage I Adult Burkitt Lymphoma\|Stage I Adult Diffuse Large Cell Lymphoma\|Stage I Adult Diffuse Mixed Cell Lymphoma\|Stage I Adult Diffuse Small Cleaved Cell Lymphoma\|Stage I Adult Hodgkin Lymphoma\|Stage I Adult Immunoblastic Large Cell Lymphoma\|Stage I Adult Lymphoblastic Lymphoma\|Stage I Chronic Lymphocytic Leukemia\|Stage I Grade 1 Follicular Lymphoma\|Stage I Grade 2 Follicular Lymphoma\|Stage I Grade 3 Follicular Lymphoma\|Stage I Mantle Cell Lymphoma\|Stage I Marginal Zone Lymphoma\|Stage I Small Lymphocytic Lymphoma\|Stage II Adult Hodgkin Lymphoma\|Stage II Chronic Lymphocytic Leukemia\|Stage III Adult Burkitt Lymphoma\|Stage III Adult Diffuse Large Cell Lymphoma\|Stage III Adult Diffuse Mixed Cell Lymphoma\|Stage III Adult Diffuse Small Cleaved Cell Lymphoma\|Stage III Adult Hodgkin Lymphoma\|Stage III Adult Immunoblastic Large Cell Lymphoma\|Stage III Adult Lymphoblastic Lymphoma\|Stage III Chronic Lymphocytic Leukemia\|Stage III Grade 1 Follicular Lymphoma\|Stage III Grade 2 Follicular Lymphoma\|Stage III Grade 3 Follicular Lymphoma\|Stage III Mantle Cell Lymphoma\|Stage III Marginal Zone Lymphoma\|Stage IV Adult Burkitt Lymphoma\|Stage IV Adult Diffuse Large Cell Lymphoma\|Stage IV Adult Diffuse Mixed Cell Lymphoma\|Stage IV Adult Diffuse Small Cleaved Cell Lymphoma\|Stage IV Adult Hodgkin Lymphoma\|Stage IV Adult Immunoblastic Large Cell Lymphoma\|Stage IV Adult Lymphoblastic Lymphoma\|Stage IV Chronic Lymphocytic Leukemia\|Stage IV Grade 1 Follicular Lymphoma\|Stage IV Grade 2 Follicular Lymphoma\|Stage IV Grade 3 Follicular Lymphoma\|Stage IV Mantle Cell Lymphoma\|Stage IV Marginal Zone Lymphoma\|Stage IV Small Lymphocytic Lymphoma\|Testicular Lymphoma\|Waldenström Macroglobulinemia	June 2013	Phase 2
NCT01481272	Polish Lymphoma Research Group	Diffuse Large B Cell Lymphoma	November 2011	Phase 2
NCT04311567	Vastra Gotaland Region\|Göteborg University	Rheumatoid Arthritis\|Interstitial Lung Disease Due to Systemic Disease (Disorder)\|RA\|ILD	November 7, 2020	Phase 4
NCT00106522	Hoffmann-La Roche	Rheumatoid Arthritis	May 2005	Phase 3
NCT00576433	Hoffmann-La Roche	Rheumatoid Arthritis	December 2007	Phase 4
NCT00002579	Scottish Cancer Therapy Network\|National Cancer Institute (NCI)	Breast Cancer	March 1993	Phase 3
NCT00074191	OHSU Knight Cancer Institute\|National Cancer Institute (NCI)	Lymphoma	January 2000	Phase 2
NCT00689845	University Hospital Southampton NHS Foundation Trust\|National Cancer Institute (NCI)	Lymphoma	June 2007	Not Applicable
NCT01281696	National Taiwan University Hospital\|Taipei Veterans General Hospital, Taiwan\|Taichung Veterans General Hospital\|Chang Gung Memorial Hospital	Breast Neoplasms\|Leptomeningeal Metastasis\|Brain Metastases	January 2011	Phase 2
NCT00446784	Pfizer	Arthritis, Rheumatoid	April 2007	Phase 1
NCT00002809	Temple University	Leukemia\|Myelodysplastic Syndromes\|Myelodysplastic+Myeloproliferative Diseases	August 1996	Phase 2
NCT00000658	National Institute of Allergy and Infectious Diseases (NIAID)\|Schering-Plough	Lymphoma, Non-Hodgkin\|HIV Infections		Phase 3
NCT01366898	PETHEMA Foundation	Acute Lymphoblastic Leukemia	June 30, 2007	Phase 4
NCT02881086	Goethe University	Acute Lymphoblastic Leukemia\|Lymphoblastic Lymphoma	August 2016	Phase 3
NCT03692416	Assiut University	Vasculitis	November 11, 2018	Phase 3
NCT04958538	Peking University People´s Hospital	Acute Graft Versus Host Disease	April 21, 2021	Phase 2
NCT01613079	Peking Union Medical College Hospital	Arthritis, Rheumatoid	May 2012	Phase 2\|Phase 3
NCT03912818	Stanford University\|AstraZeneca	Bladder Adenocarcinoma\|Bladder Mixed Adenocarcinoma\|Bladder Squamous Cell Carcinoma\|Bladder Urothelial Carcinoma\|Infiltrating Bladder Urothelial Carcinoma Sarcomatoid Variant\|Infiltrating Bladder Urothelial Carcinoma With Giant Cells\|Infiltrating Bladder Urothelial Carcinoma With Glandular Differentiation\|Infiltrating Bladder Urothelial Carcinoma With Trophoblastic Differentiation\|Infiltrating Bladder Urothelial Carcinoma, Clear Cell Variant\|Infiltrating Bladder Urothelial Carcinoma, Micropapillary Variant\|Infiltrating Bladder Urothelial Carcinoma, Nested Variant\|Infiltrating Bladder Urothelial Carcinoma, Plasmacytoid Variant	April 10, 2019	Phase 2
NCT02347332	Pierre Fabre Medicament	Recurrent or Metastatic Head and Neck Carcinoma	April 25, 2014	Phase 3
NCT04898894	St. Jude Children´s Research Hospital\|Karyopharm Therapeutics Inc\|AbbVie\|Gateway for Cancer Research	Acute Leukemia of Ambiguous Lineage in Relapse\|Acute Myeloid Leukemia, in Relapse\|Refractory Acute Leukemia of Ambiguous Lineage\|Refractory Acute Myeloid Leukemia	November 15, 2021	Phase 1
NCT01258712	Chugai Pharma Taiwan	Rheumatoid Arthritis (RA)	December 2010	Phase 3
NCT01572662	M.D. Anderson Cancer Center	Leukemia\|Acute Myeloid Leukemia\|Acute Lymphocytic Leukemia\|Chronic Myeloid Leukemia\|Chronic Lymphocytic Leukemia\|Myeloproliferative Diseases\|Non-Hodgkins Lymphoma\|Hodgkins Lymphoma\|Multiple Myeloma\|Myelodysplastic Syndrome	April 11, 2012	Phase 2
NCT03123718	Chonnam National University Hospital\|Consortium for Improving Survival of Lymphoma	DLBCL	July 1, 2017	Phase 3
NCT03171831	First Affiliated Hospital of Guangxi Medical University	Thalassemia Major	April 1, 2017	Phase 4
NCT01285817	Assistance Publique Hopitaux De Marseille	Solid Tumours.	November 2010	Phase 2
NCT00268528	Children´s Oncology Group\|National Cancer Institute (NCI)	Childhood Acute Lymphoblastic Leukemia in Remission	May 30, 2005
NCT00119301	Memorial Sloan Kettering Cancer Center\|National Cancer Institute (NCI)	Sarcoma	April 2005	Phase 1
NCT00553202	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia	January 2008	Phase 2
NCT00905034	M.D. Anderson Cancer Center\|Leadiant Biosciences, Inc.	Leukemia, Lymphocytic, Acute	March 2009	Phase 2
NCT00005047	Southwest Oncology Group\|National Cancer Institute (NCI)\|NCIC Clinical Trials Group\|University of Southern California	Bladder Cancer	August 1997	Phase 3
NCT02764762	Takeda	Crohn Disease	June 12, 2017	Phase 4
NCT04725422	Seattle Children´s Hospital\|Boston Children´s Hospital, Boston, MA, USA\|Hospital for Special Surgery, New York City, NY, USA\|Joseph M Sanzari Children´s Hospital, Hackensack University Medical Center, Hackensack, NJ, USA\|Riley Children´s Hospital, Indianapolis, IN, USA\|University of North Carolina, Chapel Hill, NC, USA\|Royal Children´s Hospital, Melbourne, Australia\|Hacettepe University, Ankara, Turkey\|Bambino Gesù Children´s Hospital, Rome, Italy\|University of British Columbia, Vancouver, BC, Canada\|Meyer Children´s Hospital, Florence, Italy\|Mansoura University	Chronic Nonbacterial Osteomyelitis\|Chronic Recurrent Multifocal Osteomyelitis	August 1, 2018
NCT02744196	Biocad	Rheumatoid Arthritis	January 2015	Phase 3
NCT01700946	St. Jude Children´s Research Hospital\|Cookies for Kids´ Cancer\|Assisi Foundation	Recurrent B-Cell Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood B-Lymphoblastic Lymphoma	April 15, 2013	Phase 2
NCT03516903	University of Sao Paulo\|Fundação de Amparo à Pesquisa do Estado de São Paulo	Myocardial Infarction, Anterior Wall\|Myocardial Remodeling, Ventricular	April 17, 2018	Phase 2\|Phase 3
NCT01878318	Hoffmann-La Roche	Rheumatoid Arthritis	June 2013	Phase 4
NCT03860844	Sanofi	Acute Lymphoblastic Leukemia\|Acute Myeloid Leukemia	August 6, 2019	Phase 2
NCT00002463	M.D. Anderson Cancer Center\|National Cancer Institute (NCI)	Brain and Central Nervous System Tumors	February 1989	Phase 2
NCT00002756	Children´s Oncology Group\|National Cancer Institute (NCI)	Leukemia	June 1996	Phase 2
NCT02205762	North American Consortium for Histiocytosis\|Histiocyte Society	Langerhans Cell Histiocytosis	July 2014	Phase 2\|Phase 3
NCT02379091	Takeda	Rheumatoid Arthritis	December 17, 2014	Phase 2
NCT00003868	Fred Hutchinson Cancer Center\|National Cancer Institute (NCI)	Leukemia	February 1999	Phase 2
NCT00000689	National Institute of Allergy and Infectious Diseases (NIAID)	Lymphoma, Non-Hodgkin\|HIV Infections		Phase 1
NCT01471444	M.D. Anderson Cancer Center\|Sanofi	Disorder Related to Bone Marrow Transplantation\|Leukemia\|Transplantation Infection	November 2, 2011	Phase 3
NCT02644044	Tel-Aviv Sourasky Medical Center	To Evaluate the Effect of Therapy With IT MTX on the Disease Course of Patients With Progressive MS	January 2016	Early Phase 1
NCT02177695	Southwest Oncology Group\|National Cancer Institute (NCI)	Bladder Cancer	July 2014	Phase 2
NCT01529827	Roswell Park Cancer Institute	Accelerated Phase Chronic Myelogenous Leukemia\|Adult Acute Lymphoblastic Leukemia in Remission\|Adult Acute Myeloid Leukemia in Remission\|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities\|Adult Acute Myeloid Leukemia With Del(5q)\|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)\|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)\|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)\|Adult Grade III Lymphomatoid Granulomatosis\|Adult Nasal Type Extranodal NK+T-cell Lymphoma\|Anaplastic Large Cell Lymphoma\|Angioimmunoblastic T-cell Lymphoma\|Aplastic Anemia\|Burkitt Lymphoma\|Childhood Acute Lymphoblastic Leukemia in Remission\|Childhood Acute Myeloid Leukemia in Remission\|Childhood Chronic Myelogenous Leukemia\|Childhood Diffuse Large Cell Lymphoma\|Childhood Grade III Lymphomatoid Granulomatosis\|Childhood Immunoblastic Large Cell Lymphoma\|Childhood Myelodysplastic Syndromes\|Childhood Nasal Type Extranodal NK+T-cell Lymphoma\|Chronic Myelomonocytic Leukemia\|Chronic Phase Chronic Myelogenous Leukemia\|Congenital Amegakaryocytic Thrombocytopenia\|Diamond-Blackfan Anemia\|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue\|Hepatosplenic T-cell Lymphoma\|Juvenile Myelomonocytic Leukemia\|Myelodysplastic+Myeloproliferative Neoplasm, Unclassifiable\|Nodal Marginal Zone B-cell Lymphoma\|Paroxysmal Nocturnal Hemoglobinuria\|Peripheral T-cell Lymphoma\|Polycythemia Vera\|Post-transplant Lymphoproliferative Disorder\|Previously Treated Myelodysplastic Syndromes\|Primary Myelofibrosis\|Recurrent Adult Acute Lymphoblastic Leukemia\|Recurrent Adult Acute Myeloid Leukemia\|Recurrent Adult Burkitt Lymphoma\|Recurrent Adult Diffuse Large Cell Lymphoma\|Recurrent Adult Diffuse Mixed Cell Lymphoma\|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma\|Recurrent Adult Grade III Lymphomatoid Granulomatosis\|Recurrent Adult Hodgkin Lymphoma\|Recurrent Adult Immunoblastic Large Cell Lymphoma\|Recurrent Adult Lymphoblastic Lymphoma\|Recurrent Adult T-cell Leukemia+Lymphoma\|Recurrent Childhood Acute Lymphoblastic Leukemia\|Recurrent Childhood Acute Myeloid Leukemia\|Recurrent Childhood Anaplastic Large Cell Lymphoma\|Recurrent Childhood Grade III Lymphomatoid Granulomatosis\|Recurrent Childhood Large Cell Lymphoma\|Recurrent Childhood Lymphoblastic Lymphoma\|Recurrent Childhood Small Noncleaved Cell Lymphoma\|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma\|Recurrent Grade 1 Follicular Lymphoma\|Recurrent Grade 2 Follicular Lymphoma\|Recurrent Grade 3 Follicular Lymphoma\|Recurrent Mantle Cell Lymphoma\|Recurrent Marginal Zone Lymphoma\|Recurrent Mycosis Fungoides+Sezary Syndrome\|Recurrent Small Lymphocytic Lymphoma\|Recurrent+Refractory Childhood Hodgkin Lymphoma\|Refractory Chronic Lymphocytic Leukemia\|Refractory Hairy Cell Leukemia\|Refractory Multiple Myeloma\|Secondary Acute Myeloid Leukemia\|Secondary Myelodysplastic Syndromes\|Secondary Myelofibrosis\|Severe Combined Immunodeficiency\|Severe Congenital Neutropenia\|Shwachman-Diamond Syndrome\|Splenic Marginal Zone Lymphoma\|T-cell Large Granular Lymphocyte Leukemia\|Waldenstrom Macroglobulinemia\|Wiskott-Aldrich Syndrome	February 28, 2012	Phase 2
NCT00367237	Merck Sharp & Dohme LLC\|Integrated Therapeutics Group	Arthritis, Psoriatic	May 2006	Phase 3
NCT02699710	Genentech, Inc.	Healthy Volunteer	September 3, 2015	Phase 1
NCT01451203	Astellas Pharma Inc\|UCB Japan Co. Ltd.	Rheumatoid Arthritis	October 11, 2011	Phase 3
NCT00001677	National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)\|National Institutes of Health Clinical Center (CC)	Arthritis, Rheumatoid\|Synovitis	June 1998	Phase 2
NCT00791531	KEMRI-Wellcome Trust Collaborative Research Program\|University of Oxford	Malaria	March 2009	Phase 1
NCT01198002	Eli Lilly and Company	Rheumatoid Arthritis	December 2010	Phase 3
NCT00734773	Northwestern University\|Pharmacyclics LLC.	Brain and Central Nervous System Tumors\|Lymphoma\|Neurotoxicity	November 2008	Early Phase 1
NCT05057130	Blokhin´s Russian Cancer Research Center	Osteosarcoma\|Neoplasms, Connective Tissue\|Neoplasms, Connective and Soft Tissue\|Sarcoma\|Sarcoma of Bone	January 10, 2022	Phase 2\|Phase 3
NCT01920737	Memorial Sloan Kettering Cancer Center\|Shire\|Duke University\|Weill Medical College of Cornell University\|Lehigh Valley Health Network	Leukemia	August 2013	Phase 2
NCT04909801	Bristol-Myers Squibb	Rheumatoid Arthritis	September 15, 2021	Phase 3
NCT04537689	Singapore General Hospital\|Translational Immunology Institute	Plaque Psoriasis	December 10, 2020	Phase 4
NCT01953770	Federal Research Institute of Pediatric Hematology, Oncology and Immunology	Childhood Acute Lymphoblastic Leukemia	February 2008	Not Applicable
NCT00199082	Nicola Goekbuget\|Goethe University	Burkitt´s Lymphoma\|Burkitt´s Leukemia\|Mediastinal Neoplasms\|Lymphoblastic Lymphoma\|Large Cell Anaplastic Lymphoma	July 2002	Phase 4
NCT01411267	Therapeutic Advances in Childhood Leukemia Consortium\|Ambit Biosciences Corporation	Lymphoblastic Leukemia, Acute, Childhood\|Myelogenous Leukemia, Acute, Childhood	September 1, 2011	Phase 1
NCT00671658	M.D. Anderson Cancer Center	Leukemia\|Acute Lymphoblastic Leukemia	November 2002	Phase 2
NCT02328755	University of Michigan Rogel Cancer Center	Acute Myeloid Leukemia	January 2015	Phase 1\|Phase 2
NCT02003222	National Cancer Institute (NCI)\|Canadian Cancer Trials Group	Acute Lymphoblastic Leukemia\|B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative	December 23, 2013	Phase 3
NCT01338987	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	Myelodysplastic Syndrome\|Acute Lymphocytic Leukemia\|Acute Myelogenous Leukemia\|Chronic Myelogenous Leukemia\|Chronic Myelomonocytic Leukemia	April 19, 2011	Phase 2
NCT00002657	Southwest Oncology Group\|National Cancer Institute (NCI)\|Eastern Cooperative Oncology Group	Lymphoma\|Multiple Myeloma and Plasma Cell Neoplasm	May 1995	Phase 2

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : ≥ 50 mg/mL ( 110.03 mM )

* "≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.2005 mL	11.0026 mL	22.0051 mL
5 mM	0.4401 mL	2.2005 mL	4.4010 mL
10 mM	0.2201 mL	1.1003 mL	2.2005 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (5.50 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (5.50 mM); Clear solution
3.

Add each solvent one by one: 5% DMSO >> 40% PEG300 >> 5% Tween-80 >> 50% saline

Solubility: ≥ 2.5 mg/mL (5.50 mM); Clear solution
4.

Add each solvent one by one: 5% DMSO >> 95% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (5.50 mM); Clear solution

* All of the co-solvents are available by MCE.

References

Synonyms

L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-

Glutamic acid, N-[p-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, L-(+)-

N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid

CL 14377

Amethopterin

4-Amino-10-methylfolic acid

4-Amino-N¹⁰-methylpteroylglutamic acid

N-[p-[[2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-(+)-glutamic acid

Methotrexate

MTX

NSC 740

R 9985

Antifolan

L-Methotrexate

Amethopterine

4-Amino-N¹⁰-methylfolic acid

(+)-Amethopterin

L-Amethopterin

Methotrexat-Ebewe

Ledertrexate

Emtexate

Mexate

Metatrexan

EMT 25299

Methylaminopterin

Rheumatrex

Methoxtrexate

Trexall

Emthexate PF

Emtrexate

(2S)-2-[[4-[[(2,4-Diaminopteridin-6-yl)methyl]methylamino]benzoyl]amino]pentanedioic acid

Folitrax

Folex PFS

Folex

Mexate-AQ

Methotrexate LPF

Trilem

Zexate

Oncotrex

Methocip

Merex

Caditrex

Remtrex

Metorex

Methocel

LMTX

Nordimet

Jylamvo