[CAS NO. 60133-18-8] Ercalcitriol

Name: Ercalcitriol
Brand: Arctom Scientific
SKU: HY-32350

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PRODUCTS SPECIFICATIONS [60133-18-8]

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Catalog

HY-32350

Brand

MCE

CAS

60133-18-8

DESCRIPTION [60133-18-8]

Overview

MDL	-
Molecular Weight	428.65
Molecular Formula	C28H44O3
SMILES	C=C1[C@H](C[C@@H](C/C1=C/C=C2[C@]3([C@@](C)([C@H](CC3)[C@@H](/C=C/[C@@H](C(C)(O)C)C)C)CCC/2)[H])O)O

For research use only. We do not sell to patients.

1 Publications Citing Use of MCE

[1]J Lipid Res. 2019 May;60(5):1058-1064.

Summary

Ercalcitriol (1α,25-Dihydroxy Vitamin D2) is an active metabolite of vitamin D2.

IC50 & Target

Human Endogenous Metabolite

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light, stored under nitrogen

* The compound is unstable in solutions, freshly prepared is recommended.

Solvent & Solubility

In Vitro:

DMSO : ≥ 50 mg/mL ( 116.65 mM )

* "≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.3329 mL	11.6645 mL	23.3291 mL
5 mM	0.4666 mL	2.3329 mL	4.6658 mL
10 mM	0.2333 mL	1.1665 mL	2.3329 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (5.83 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (5.83 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO >> 90% corn oil

Solubility: ≥ 2.5 mg/mL (5.83 mM); Clear solution

* All of the co-solvents are available by MCE.

References

Synonyms

1,3-Cyclohexanediol, 4-methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,2E)-5-hydroxy-1,4,5-trimethyl-2-hexen-1-yl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1R,3S,5Z)-

9,10-Secoergosta-5,7,10(19),22-tetraene-1,3,25-triol, (1α,3β,5Z,7E,22E)-

(1R,3S,5Z)-4-Methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,2E)-5-hydroxy-1,4,5-trimethyl-2-hexen-1-yl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol

1α,25-Dihydroxyvitamin D₂

1α,25-Dihydroxycalciferol

1α,25-Dihydroxyergocalciferol

Ercalcitriol

Ro 17-6218

1,25-Dihydroxyergocalciferol

1,25-Dihydroxyvitamin D₂

1,25-Dihydroxycalciferol