[CAS NO. 82209-74-3] Andrograpanin
PRODUCTS SPECIFICATIONS [82209-74-3]
DESCRIPTION [82209-74-3]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 318.45 |
| Molecular Formula | C20H30O3 |
| SMILES | O=C1OCC=C1CC[C@@H]2C(CC[C@]3([H])[C@](C)(CO)CCC[C@@]23C)=C |
Summary
In Vitro
Andrograpanin exhibits anti-inflammatory properties in lipopolysaccharide-induced macrophage cells through down-regulating the p38 MAPKs signaling pathways
[1]
.
Andrograpanin enhances chemokine SDF-1α-induced leukocytes chemotaxis in Jurkat, THP-1 and PBL cells
[2]
.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 100 mg/mL ( 314.02 mM ; ultrasonic and warming and heat to 60°C)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 3.1402 mL | 15.7011 mL | 31.4021 mL |
| 5 mM | 0.6280 mL | 3.1402 mL | 6.2804 mL |
| 10 mM | 0.3140 mL | 1.5701 mL | 3.1402 mL |
References
- [1] 1.Li-Li Ji, et al.Andrograpanin, a compound isolated from anti-inflammatory traditional Chinese medicine Andrographis paniculata, enhances chemokine SDF-1alpha-induced leukocytes chemotaxis. J Cell Biochem. 2005 Aug 1;95(5):970-8.
- [2] 2.Jun Liu, et al. Andrograpanin, isolated from Andrographis paniculata, exhibits anti-inflammatory property in lipopolysaccharide-induced macrophage cells through down-regulating the p38 MAPKs signaling pathways. Int Immunopharmacol. 2008 Jul;8(7):951-8.
Synonyms
