[CAS NO. 870487-09-5] Boc-Val-Cit-PAB
PRODUCTS SPECIFICATIONS [870487-09-5]
DESCRIPTION [870487-09-5]
Overview
| MDL | MFCD22200277 |
|---|---|
| Molecular Weight | 479.57 |
| Molecular Formula | C23H37N5O6 |
| SMILES | OCC(C=C1)=CC=C1NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(OC(C)(C)C)=O)=O)=O |
Summary
Boc-Val-Cit-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1] .
IC50 & Target
|
Protease Cleavable |
Cleavable |
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 100 mg/mL ( 208.52 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 2.0852 mL | 10.4260 mL | 20.8520 mL |
| 5 mM | 0.4170 mL | 2.0852 mL | 4.1704 mL |
| 10 mM | 0.2085 mL | 1.0426 mL | 2.0852 mL |
