[CAS NO. 912288-64-3] YHO-13351freebase

Name: YHO-13351freebase
Brand: Arctom Scientific
SKU: HY-12758A

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PRODUCTS SPECIFICATIONS [912288-64-3]

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Catalog

HY-12758A

Brand

MCE

CAS

912288-64-3

DESCRIPTION [912288-64-3]

Overview

MDL	-
Molecular Weight	483.62
Molecular Formula	C26H33N3O4S
SMILES	N#C/C(C1=CC=C(OC)C(OC)=C1)=C\C2=CC=C(N3CCC(OC(CN(CC)CC)=O)CC3)S2

For research use only. We do not sell to patients.

Summary

YHO-13351 free base is the prodrug of YHO-13177, which is a potent and specific inhibitor of BCRP .

Appearance

Solid

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 206.77 mM ; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.0677 mL	10.3387 mL	20.6774 mL
5 mM	0.4135 mL	2.0677 mL	4.1355 mL
10 mM	0.2068 mL	1.0339 mL	2.0677 mL

* Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

Solubility: ≥ 2.5 mg/mL (5.17 mM); Clear solution

* All of the co-solvents are available by MCE.