[CAS NO. 698394-73-9]  Vercirnon

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PRODUCTS SPECIFICATIONS [698394-73-9]

Store
Catalog
SLK-E0395
Brand
Selleck
CAS
698394-73-9

DESCRIPTION [698394-73-9]

Overview

MDLMFCD28137610
Molecular Weight444.93
Molecular FormulaC22H21ClN2O4S
SMILESO=S(C1=CC=C(C(C)(C)C)C=C1)(NC2=CC=C(Cl)C=C2C(C3=CC=[N+]([O-])C=C3)=O)=O

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Description

Vercirnon (GSK1605786A, CCX-282, Traficet-EN), an orally bioavailable, selective, and potent antagonist of CCR9, is an equipotent inhibitor of CCL25-directed chemotaxis of both splice forms of CCR9.

Targets

CCR9B [1]
(in the chemotaxis assays)
CCR9A [1]
(in the chemotaxis assays)
2.6 nM2.8 nM