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PRODUCTS SPECIFICATIONS [1424635-83-5]
Store
Catalog
SLK-E1061
Brand
Selleck
CAS
1424635-83-5
DESCRIPTION [1424635-83-5]
Overview
MDL
-
Molecular Weight
334.40
Molecular Formula
C18H14N4OS
SMILES
O=C(C1=CNC2=NC=CC=C21)/N=C3SC=CN\3CC4=CC=CC=C4
For research use only.
Storage
3 years,-20°C,powder 1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Description
TRULI inhibits both with a IC50 of 0.2 nM, suppresses Yap phosphorylation, induces cell proliferation in several cell lines and tissues, and promotes the initial stages of proliferative regeneration of the sensory receptors in the inner ear.
TRULI acts as an inhibitor of Lats kinases in vitro, suppresses Yap phosphorylation, induces cell proliferation in several cell lines and tissues, and promotes the initial stages of proliferative regeneration of the sensory receptors in the inner ear.