[CAS NO. 1538593-71-3]  Piperazine Erastin

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PRODUCTS SPECIFICATIONS [1538593-71-3]

Store
Catalog
SLK-E1063
Brand
Selleck
CAS
1538593-71-3

DESCRIPTION [1538593-71-3]

Overview

MDL-
Molecular Weight645.19
Molecular FormulaC35H41ClN6O4
SMILES-

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM1.5499 mL7.7497 mL15.4993 mL
5 mM0.3100 mL1.5499 mL3.0999 mL
10 mM0.1550 mL0.7750 mL1.5499 mL
50 mM0.0310 mL0.1550 mL0.3100 mL

Description

Piperazine Erastin is an analog of Erastin, which can induces ferroptosis in cancer cells, an iron-dependent form of nonapoptotic cell death.

In vitro

Piperazine Erastin, an analogue of Erastin, induces ferroptosis of cancer cells and upregulates PTGS2 in BJeLR cells that is suppressed when cotreatment of vitamin E.