[CAS NO. 251945-92-3] Derenofylline (SLV320)

Name: Derenofylline (SLV320)
Brand: Arctom Scientific
SKU: SLK-S0272

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PRODUCTS SPECIFICATIONS [251945-92-3]

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Catalog

SLK-S0272

Brand

Selleck

CAS

251945-92-3

DESCRIPTION [251945-92-3]

Overview

MDL	MFCD12756289
Molecular Weight	308.38
Molecular Formula	C18H20N4O
SMILES	N(C1=C2C(=NC(=N1)C3=CC=CC=C3)NC=C2)[C@@H]4CC[C@@H](O)CC4

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	3.2428 mL	16.2138 mL	32.4275 mL
5 mM	0.6486 mL	3.2428 mL	6.4855 mL
10 mM	0.3243 mL	1.6214 mL	3.2428 mL
50 mM	0.0649 mL	0.3243 mL	0.6486 mL

Description

Derenofylline (SLV320) is a selective and potent antagonist with Ki of 1 nM. Derenofylline shows selective for adenosine A1 over A2A, A2B, and A3 receptors with Ki of 398 nM, 3981 nM, and 200 nM, respectively.

Targets

Adenosine A1 receptor ^[1]
(Cell-free assay)

1 nM(Ki)

References

[1] P Kalk, et al. Br J Pharmacol. 2007 Aug;151(7):1025-32.

Synonyms

Cyclohexanol, 4-[(2-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-, trans-

Cyclohexanol, 4-[(2-phenyl-1H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-, trans-

trans-4-[(2-Phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexanol

4-[(4-trans-Hydroxycyclohexyl)amino]-2-phenyl-7H-pyrrolo[2,3-d]pyrimidine

SLV 320

Derenofylline