[CAS NO. 1507370-20-8] BC-1215
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PRODUCTS SPECIFICATIONS [1507370-20-8]
Store
Catalog
SLK-S0322
Brand
Selleck
CAS
1507370-20-8
DESCRIPTION [1507370-20-8]
Overview
| MDL | MFCD28118991 |
|---|---|
| Molecular Weight | 394.51 |
| Molecular Formula | C26H26N4 |
| SMILES | C1(CNCCNCC2=CC=C(C3=NC=CC=C3)C=C2)=CC=C(C4=NC=CC=C4)C=C1 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Description
BC-1215 is an inhibitor of with IC50 of 0.9 μg/mL and LC50 of 87 μg/ml for IL-1β release. BC-1215 inhibits the Fbxo3-TRAF activation pathway by destabilizing TRAF1-6.
In vitro
BC-1215, a Fbxo3 inhibitor, inhibits the Fbxo3-TRAF activation pathway by destabilizing TRAF1-6 proteins. Also, BC-1215 inhibits LPS-induced secretion of a broad spectrum of T1 panel cytokines in human PBMC.
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