[CAS NO. 289480-64-4] Treprostinil sodium

Name: Treprostinil sodium
Brand: Arctom Scientific
SKU: SLK-S0325

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PRODUCTS SPECIFICATIONS [289480-64-4]

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Catalog

SLK-S0325

Brand

Selleck

CAS

289480-64-4

DESCRIPTION [289480-64-4]

Overview

MDL	MFCD08141832
Molecular Weight	412.49
Molecular Formula	C23H33NaO5
SMILES	C(C[C@H](CCCCC)O)[C@@H]1[C@@]2([C@@](CC=3C(C2)=CC=CC3OCC(O)=O)(C[C@H]1O)[H])[H].[Na]

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	2.4243 mL	12.1215 mL	24.2430 mL
5 mM	0.4849 mL	2.4243 mL	4.8486 mL
10 mM	0.2424 mL	1.2122 mL	2.4243 mL
50 mM	0.0485 mL	0.2424 mL	0.4849 mL

Description

Treprostinil sodium (UT-15, Remodulin, Orenitram, Tyvaso, Trevyent) is a potent agonist of , and receptors with Ki 4.4 nM, 3.6 nM and 32 nM, respectively.

Targets

EP2 ^[1] (Cell-free assay)	DP1 ^[1] (Cell-free assay)	IP ^[1] (Cell-free assay)
3.6 nM(Ki)	4.4 nM(Ki)	32 nM(Ki)

References

[1] Brendan J Whittle, et al. Biochem Pharmacol. 2012 Jul 1;84(1):68-75.

Synonyms

Acetic acid, 2-[[(1R,2R,3aS,9aS)-2,3,3a,4,9,9a-hexahydro-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1H-benz[f]inden-5-yl]oxy]-, sodium salt (1:1)

Acetic acid, [[(1R,2R,3aS,9aS)-2,3,3a,4,9,9a-hexahydro-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1H-benz[f]inden-5-yl]oxy]-, monosodium salt

Remodulin

Treprostinil sodium

UT 15

UT 15 (pharmaceutical)

Trepulmix