[CAS NO. 163042-96-4]  Namodenoson (CF-102)

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PRODUCTS SPECIFICATIONS [163042-96-4]

Store
Catalog
SLK-S0498
Brand
Selleck
CAS
163042-96-4

DESCRIPTION [163042-96-4]

Overview

MDLMFCD01861178
Molecular Weight544.73
Molecular FormulaC18H18ClIN6O4
SMILESO=C([C@H]1O[C@@H](N2C=NC3=C(NCC4=CC=CC(I)=C4)N=C(Cl)N=C23)[C@H](O)[C@@H]1O)NC

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM1.8358 mL9.1789 mL18.3577 mL
5 mM0.3672 mL1.8358 mL3.6715 mL
10 mM0.1836 mL0.9179 mL1.8358 mL
50 mM0.0367 mL0.1836 mL0.3672 mL

Description

Namodenoson (CF-102, 2-Cl-IB-MECA) is an orally bioavailable and selective agonist of the with Ki of 0.33 nM. Namodenoson exerts an anti‑NASH effect mediated via the de‑regulation of the PI3K/NF‑κB/Wnt/β‑catenin signaling pathway.

Targets

A3AR [1]
(Cell-free assay)
0.33 nM(Ki)

In vitro

Namodenoson (CF-102, 2-Cl-IB-MECA) is an orally bioavailable and selective agonist of the A3 adenosine receptor (A3AR).