[CAS NO. 148451-96-1] L-732138

Name: L-732138
Brand: Arctom Scientific
SKU: SLK-S0772

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PRODUCTS SPECIFICATIONS [148451-96-1]

Store

Catalog

SLK-S0772

Brand

Selleck

CAS

148451-96-1

DESCRIPTION [148451-96-1]

Overview

MDL	MFCD00237267
Molecular Weight	472.38
Molecular Formula	C22H18F6N2O3
SMILES	C([C@@H](C(OCC1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)=O)NC(C)=O)C=2C=3C(NC2)=CC=CC3

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Description

L-732138 (L-732,138) is a selective, potent and competitive antagonist of . L-732138 inhibits the binding of I-SP to the human NK-1 receptor stably expressed in CHO cells with IC50 of 2.3 nM.

Targets

NK-1 receptor ^[1]
(in CHO cells)

2.3 nM

References

[1] M A Cascieri, et al. J Biol Chem. 1994 Mar 4;269(9):6587-91.

Synonyms

L-Tryptophan, N-acetyl-, [3,5-bis(trifluoromethyl)phenyl]methyl ester

L 732138

N-Acetyltryptophan 3,5-bis(trifluoromethyl)benzyl ester

N-Acetyl-L-tryptophan 3,5-bis(trifluoromethyl)benzyl ester

(S)-3,5-Bis(trifluoromethyl)benzyl 2-acetamido-3-(1H-indol-3-yl)propanoate