[CAS NO. 1188296-52-7]  PF 4800567

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PRODUCTS SPECIFICATIONS [1188296-52-7]

Store
Catalog
SLK-S2249
Brand
Selleck
CAS
1188296-52-7

DESCRIPTION [1188296-52-7]

Overview

MDLMFCD22123245
Molecular Weight359.81
Molecular FormulaC17H18ClN5O2
SMILESC(OC1=CC(Cl)=CC=C1)C=2C=3C(N(N2)C4CCOCC4)=NC=NC3N

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.7792 mL13.8962 mL27.7924 mL
5 mM0.5558 mL2.7792 mL5.5585 mL
10 mM0.2779 mL1.3896 mL2.7792 mL
50 mM0.0556 mL0.2779 mL0.5558 mL

Description

PF 4800567 is a novel and potent inhibitor of (IC50=32 nM) with greater than 20-fold selectivity over (IC50=711 nM).

Targets

casein kinase 1 epsilon [1]
(Cell-free assay)
casein kinase 1 delta [1]
32 nM711 nM


Synonyms

1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-[(3-chlorophenoxy)methyl]-1-(tetrahydro-2H-pyran-4-yl)-
3-[(3-Chlorophenoxy)methyl]-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
PF 4800567