[CAS NO. 117-39-5] Quercetin (NSC 9221)
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PRODUCTS SPECIFICATIONS [117-39-5]
Store
Catalog
SLK-S2391
Brand
Selleck
CAS
117-39-5
DESCRIPTION [117-39-5]
Overview
| MDL | MFCD00006828 |
|---|---|
| Molecular Weight | 302.24 |
| Molecular Formula | C15H10O7 |
| SMILES | O=C1C=2C(OC(=C1O)C3=CC(O)=C(O)C=C3)=CC(O)=CC2O |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.3086 mL | 16.5431 mL | 33.0863 mL |
| 5 mM | 0.6617 mL | 3.3086 mL | 6.6173 mL |
| 10 mM | 0.3309 mL | 1.6543 mL | 3.3086 mL |
| 50 mM | 0.0662 mL | 0.3309 mL | 0.6617 mL |
Description
Quercetin (NSC 9221, Sophoretin, C.I. 75720), a natural flavonoid present in vegetables, fruit and wine, is a stimulator of recombinant and also a inhibitor with of 2.4-5.4 μM. Quercetin induces , and protective . Phase 4.
Targets
In vitro
Quercetin is a type of plant-based chemical, or phytochemical, known as a flavonol and a plant-derived flavonoid found in fruits, vegetables, leaves and grains. It also may be used as an ingredient in supplements, beverages or foods. In several studies, it may have anti-inflammatory and antioxidant properties, and it is being investigated for a wide range of potential health benefits. Quercetin (Sophoretin) is a PI3K inhibitor with IC50 of 2.4 – 5.4 μM. It strongly abrogated PI3K and Src kinases, mildly inhibited Akt1/2, and slightly affected PKC, p38 and ERK1/2. Quercetin inhibits TNF-induced LDH% release, EC-dependent neutrophils adhesion to bovine pulmonary artery endothelial cells (BPAEC), and BPAEC DNA synthesis and proliferation.
References
Synonyms
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-
Flavone, 3,3′,4′,5,7-pentahydroxy-
Flavone, 3,4′,5,5′,7-pentahydroxy-
2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one
C.I. 75670
Meletin
3,5,7,3′,4′-Pentahydroxyflavone
Quercetin
Quercetine
Quercetol
Quertine
Sophoretin
Xanthaurine
3,3′,4′,5,7-Pentahydroxyflavone
Cyanidelonon 1522
Quertin
NSC 57655
NSC 9219
2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-benzopyran-4-one
Corvitin
Korvitin
3′-Hydroxykaempferol
LDN 0052529
Lipoflavon
3,5,7-Trihydroxy-2-(3,4-dihydroxyphenyl)-4H-chromen-4-one
2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one
2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one
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