[CAS NO. 31993-01-8] SIB 1757
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PRODUCTS SPECIFICATIONS [31993-01-8]
Store
Catalog
SLK-S2645
Brand
Selleck
CAS
31993-01-8
DESCRIPTION [31993-01-8]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 213.24 |
| Molecular Formula | C12H11N3O |
| SMILES | N(=NC1=CC=CC=C1)C2=C(O)C=CC(C)=N2 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 4.6896 mL | 23.4478 mL | 46.8955 mL |
| 5 mM | 0.9379 mL | 4.6896 mL | 9.3791 mL |
| 10 mM | 0.4690 mL | 2.3448 mL | 4.6896 mL |
| 50 mM | 0.0938 mL | 0.4690 mL | 0.9379 mL |
Description
SIB 1757 is a highly selective, noncompetitive antagonist of with IC50 of 0.4 μM at hmGluR5 compared with >30 µM at hmGluR1b, hmGluR2, hmGluR4, hmGluR6, hmGluR7 and hmGluR8.
Targets
| mGluR5 [1] (Cell-free assay) |
| 0.4 μM |
Synonyms
3-Pyridinol, 6-methyl-2-(2-phenyldiazenyl)-
3-Pyridinol, 6-methyl-2-(phenylazo)-
6-Methyl-2-(2-phenyldiazenyl)-3-pyridinol
3-Hydroxy-6-methyl-2-phenylazopyridine
SIB 1757
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