[CAS NO. 1821387-73-8] CU-T12-9
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PRODUCTS SPECIFICATIONS [1821387-73-8]
Store
Catalog
SLK-S2979
Brand
Selleck
CAS
1821387-73-8
DESCRIPTION [1821387-73-8]
Overview
| MDL | - |
|---|---|
| Molecular Weight | 362.31 |
| Molecular Formula | C17H13F3N4O2 |
| SMILES | - |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.7601 mL | 13.8003 mL | 27.6007 mL |
| 5 mM | 0.5520 mL | 2.7601 mL | 5.5201 mL |
| 10 mM | 0.2760 mL | 1.3800 mL | 2.7601 mL |
| 50 mM | 0.0552 mL | 0.2760 mL | 0.5520 mL |
Description
CU-T12-9 is a specific agonist of with EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay. CU-T12-9 activates both the innate and the adaptive immune systems. CU-T12-9 signals through and invokes an elevation of the downstream effectors , , and .
Targets
| TLR 1/2 [1] (HEK-Blue hTLR2 SEAP assay) |
| 52.9 nM(EC50) |
In vitro
CU-T12-9 specifically induces TLR1/2 activation, and facilitates the TLR1/2 heterodimeric complex formation, which in turn activates the downstream NF-κB signaling.
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