[CAS NO. 738-70-5] Trimethoprim
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PRODUCTS SPECIFICATIONS [738-70-5]
Store
Catalog
SLK-S3129
Brand
Selleck
CAS
738-70-5
DESCRIPTION [738-70-5]
Overview
| MDL | MFCD00036761 |
|---|---|
| Molecular Weight | 290.32 |
| Molecular Formula | C14H18N4O3 |
| SMILES | C(C1=CC(OC)=C(OC)C(OC)=C1)C=2C(N)=NC(N)=NC2 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.4445 mL | 17.2224 mL | 34.4448 mL |
| 5 mM | 0.6889 mL | 3.4445 mL | 6.8890 mL |
| 10 mM | 0.3444 mL | 1.7222 mL | 3.4445 mL |
| 50 mM | 0.0689 mL | 0.3444 mL | 0.6889 mL |
Description
Trimethoprim (BW 56-72, NIH 204, NSC-106568) is a bacteriostatic antibiotic mainly used in the prophylaxis and treatment of urinary tract infections.
In vitro
Trimethoprim acts by interfering with the action of bacterial dihydrofolate reductase, inhibiting synthesis of tetrahydrofolic acid. The Inhibition starves the bacteria of nucleotides necessary for DNA replication causing, in certain circumstances, cell lethality due to thymineless death.
References
Synonyms
2,4-Pyrimidinediamine, 5-[(3,4,5-trimethoxyphenyl)methyl]-
Pyrimidine, 2,4-diamino-5-(3,4,5-trimethoxybenzyl)-
5-[(3,4,5-Trimethoxyphenyl)methyl]-2,4-pyrimidinediamine
BW 56-72
2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine
Syraprim
Trimethoprim
NIH 204
2,4-Diamino-5-(3′,4′,5′-trimethoxybenzyl)pyrimidine
Trimethioprim
Trimetoprim
Triprim
Trimpex
Trimanyl
Instalac
Trimogal
Wellcoprim
Monotrim
Proloprim
Tiempe
Trimopan
Uretrim
NSC 106568
Infectotrimet
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