[CAS NO. 30197-14-9]  Desoxyrhaponticin

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PRODUCTS SPECIFICATIONS [30197-14-9]

Store
Catalog
SLK-S3300
Brand
Selleck
CAS
30197-14-9

DESCRIPTION [30197-14-9]

Overview

MDLMFCD00063444
Molecular Weight404.41
Molecular FormulaC21H24O8
SMILESO[C@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)[C@@H]1OC2=CC(/C=C/C3=CC=C(OC)C=C3)=CC(O)=C2

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.4727 mL12.3637 mL24.7274 mL
5 mM0.4945 mL2.4727 mL4.9455 mL
10 mM0.2473 mL1.2364 mL2.4727 mL
50 mM0.0495 mL0.2473 mL0.4945 mL

Description

Desoxyrhaponticin (DC, DES), a stilbene glycoside from Rheum tanguticum Maxim. ex Balf. (rhubarb) which is a traditional Chinese nutritional food, is a inhibitor. Desoxyrhaponticin (DC, DES) is also a competitive inhibitor of uptake with IC50 of 148.3 μM and 30.9 μM in rabbit intestinal membrane vesicles and in rat everted gut sleeves, respectively. Desoxyrhaponticin has apoptotic effect on human cancer cells.

Targets

FAS/FASN [1]glucose [2]
(in rat everted gut sleeves)
glucose [2]
(in rabbit intestinal membrane vesicles)
30.9 μM148.3 μM