Overview MDL - Molecular Weight 328.43 Molecular Formula C18H20N2O2S SMILES NCCCSC1=C(C=C(OC)C=C2)C2=NC3=CC=C(OC)C=C31
For research use only.
Storage 3 years,-20°C,powder 1 years,-80°C,in solvent
Shipping Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions Concentration Volume Mass 1 mg 5 mg 10 mg 1 mM 3.0448 mL 15.2239 mL 30.4479 mL 5 mM 0.6090 mL 3.0448 mL 6.0896 mL 10 mM 0.3045 mL 1.5224 mL 3.0448 mL 50 mM 0.0609 mL 0.3045 mL 0.6090 mL
Description LDN-192960 (Compd 1) is a potent inhibitor of and with IC50 of 10 nM and 48 nM, respectively.
Targets Haspin [1] (Cell-free assay) DYRK2 [1] (Cell-free assay) 10 nM 48 nM
In vitro LDN-192960 (Compd 1) exerts functional inhibitory activity against Haspin and Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) with IC50s of 10 nM and 48 nM.