[CAS NO. 183204-72-0] Tipiracil hydrochloride

Name: Tipiracil hydrochloride
Brand: Arctom Scientific
SKU: SLK-S3731

Ships within

Stock

Price

Qty

Total

$0.00

Please click "REQUEST A QUOTE" button if you need other sizes or custom synthesis

request a quote

If there is no stock, or you need other sizes or custom synthesis, please:

PRODUCTS SPECIFICATIONS [183204-72-0]

Store

Catalog

SLK-S3731

Brand

Selleck

CAS

183204-72-0

DESCRIPTION [183204-72-0]

Overview

MDL	MFCD01571384
Molecular Weight	279.12
Molecular Formula	C9H11ClN4O2.HCl
SMILES	C(C1=C(Cl)C(=O)NC(=O)N1)N2C(=N)CCC2.Cl

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	3.5827 mL	17.9134 mL	35.8269 mL
5 mM	0.7165 mL	3.5827 mL	7.1654 mL
10 mM	0.3583 mL	1.7913 mL	3.5827 mL
50 mM	0.0717 mL	0.3583 mL	0.7165 mL

Description

Tipiracil (MA-1) is an inhibitor of , the enzyme that degrades trifluridine into trifluorothymidine. Its combination with trifluridine increases the bioavailability of trifluridine.

Targets

thymidine phosphorylase ^[1]

References

[1] Cleary JM, et al. Invest New Drugs. 2017, 35(2):189-197.

Synonyms

2,4(1H,3H)-Pyrimidinedione, 5-chloro-6-[(2-imino-1-pyrrolidinyl)methyl]-, hydrochloride (1:1)

2,4(1H,3H)-Pyrimidinedione, 5-chloro-6-[(2-imino-1-pyrrolidinyl)methyl]-, monohydrochloride

TPI hydrochloride

TAS 1-462

Tipiracil hydrochloride

5-Chloro-6-[(2-iminopyrrolidin-1-yl)methyl]pyrimidine-2,4(1H,3H)-dione hydrochloride