[CAS NO. 80418-24-2] Notoginsenoside R1

Name: Notoginsenoside R1
Brand: Arctom Scientific
SKU: SLK-S3785

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PRODUCTS SPECIFICATIONS [80418-24-2]

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Catalog

SLK-S3785

Brand

Selleck

CAS

80418-24-2

DESCRIPTION [80418-24-2]

Overview

MDL	MFCD00210535
Molecular Weight	933.13
Molecular Formula	C47H80O18
SMILES	C[C@]12[C@@]3(C)[C@@]([C@@]([C@@](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)(CCC=C(C)C)C)(CC3)[H])([C@H](O)C[C@@]1([C@]5(C)[C@@]([C@@H](O[C@H]6[C@H](O[C@H]7[C@H](O)[C@@H](O)[C@H](O)CO7)[C@@H](O)[C@H](O)[C@@H](CO)O6)C2)(C(C)(C)[C@@H](O)CC5)[H])[H])[H]

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	1.0717 mL	5.3583 mL	10.7166 mL
5 mM	0.2143 mL	1.0717 mL	2.1433 mL
10 mM	0.1072 mL	0.5358 mL	1.0717 mL
50 mM	0.0214 mL	0.1072 mL	0.2143 mL

Description

Notoginsenoside R1 (Sanchinoside R1) is the main ingredient with cardiovascular activity in Panax notoginseng. It inhibits TNF-α-induced PAI-1 overexpression via extracellular signal-related kinases (ERK1/2) and phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling pathways.

Targets

PAI-1 ^[1]

ERK1 ^[1]

ERK2 ^[1]

References

[1] Hong-Sheng Zhang, Sheng-Qi Wang. Vascul Pharmacol. 2006 Apr;44(4):224-30.

Synonyms

β-D-Glucopyranoside, (3β,6α,12β)-20-(β-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-β-D-xylopyranosyl-

Dammarane, β-D-glucopyranoside deriv.

(3β,6α,12β)-20-(β-D-Glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-β-D-xylopyranosyl-β-D-glucopyranoside

Notoginsenoside R₁

Sanchinoside R₁

Sanqi glucoside R1