[CAS NO. 1401-55-4] Tannic acid

Name: Tannic acid
Brand: Arctom Scientific
SKU: SLK-S3951

Ships within

Stock

Price

Qty

Total

$0.00

Please click "REQUEST A QUOTE" button if you need other sizes or custom synthesis

request a quote

If there is no stock, or you need other sizes or custom synthesis, please:

PRODUCTS SPECIFICATIONS [1401-55-4]

Store

Catalog

SLK-S3951

Brand

Selleck

CAS

1401-55-4

DESCRIPTION [1401-55-4]

Overview

MDL	-
Molecular Weight	1701.2
Molecular Formula	C76H52O46
SMILES	-

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Description

Tannic acid (Gallotannic acid), a polyphenolic compound, is a inhibitor with antiangiogenic, anti-inflammatory and antitumor activity.

Targets

CXCR4 ^[1]

In vitro

Tannic acid, at nontoxic concentrations, specifically inhibits CXCL12-induced human monocyte migration (IC50, 7.5 μg/ml) but does not inhibit CCL2-, CCL3-, CCL5-, formylmethionylleucylphenylalanine (fMLP)-, or C5a-induced migration. The compound markedly blocks CXCL12 binding to THP-1 cells (IC50, 0.36 μg/ml). Tannic acid also inhibits CXCL12-induced, but not epidermal growth factor-induced, migration of MDA 231 breast tumor cells. Additionally, 0.5 μg/ml of tannic acid selectively inhibits CXCL12-mediated, but not basic fibroblast growth factor- or endothelial cell growth supplement-mediated, bovine aorta endothelial cell capillary tube formation.

In vivo

Given in drinking water, tannic acid enhances the survival rate of mice bearing syngeneic tumors.

References

[1] Chen X, et al. Clin Cancer Res. 2003, 9(8):3115-23.

Synonyms

Tannins

Tannic acids

Tannin analysis

Sunlife TN

Hifix SL

Tanaphen P 500

Tanex RS 93

Hifix SLA

Floctan 1

Floctan 3

Fresh Shiraimatsu FS 500M

MP-TR

TW 75

Brewtan

Tanal 1

AL

AL (tannin)

Resorcinex Pecan Tannin 9901L

Vitanil B

Quertanil

Vitanil IM

Weibull

Tannic Acid X

F-Tannin

Tannic Acid KT

Tannin

Gallotannic acid

Gallotannin

Tannic acid AL

Lexsod P

Tannic acid

FS 500M

Textan 3

Colatan GT 100

Bondtite 345

Excellence Vintage

Kakitafu

Tannic Acid ME

Bondtite 645

Arbor Lock 20

UT 10

UT 10 (tannin)

SV 82

Makubunri Seisei Kaki Tannin H 1

Pancil

Brewtan C

Tanal 02C

Tanex A-FCC

Hifix SW-A

Hifix 45

BM 539

Bondtite 241

Pancil FG 30

DT-R 240

Pancil FG 22

Crown ATO

Pancil FG 70

Fintan OP

Tru/tan

HLE 100

Pancil PO 10

Enoxil

Basyntan AS

Baxindan AS

Galalcool

Tanigan PKA-S

JOM

Bondtite 945

Syntan WT

SETA TUN

Retan MD