[CAS NO. 61-12-1] Dibucaine HCl

Name: Dibucaine HCl
Brand: Arctom Scientific
SKU: SLK-S4038

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PRODUCTS SPECIFICATIONS [61-12-1]

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Catalog

SLK-S4038

Brand

Selleck

CAS

61-12-1

DESCRIPTION [61-12-1]

Overview

MDL	-
Molecular Weight	379.92
Molecular Formula	C20H29N3O2.HCl
SMILES	C(NCCN(CC)CC)(=O)C=1C2=C(N=C(OCCCC)C1)C=CC=C2.Cl

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	2.6321 mL	13.1607 mL	26.3213 mL
5 mM	0.5264 mL	2.6321 mL	5.2643 mL
10 mM	0.2632 mL	1.3161 mL	2.6321 mL
50 mM	0.0526 mL	0.2632 mL	0.5264 mL

Description

Dibucaine HCl (Cinchocaine) is a local anesthetics.

Targets

Sodium channel ^[2]

In vitro

Dibucaine (Cinchocaine) HCl is one of the most potent and toxic of the long-acting local anesthetics. Dibucaine (Cinchocaine) HCl blocks both the initiation and conduction of nerve impulses by decreasing the neuronal membrane's permeability to sodium ions. This reversibly stabilizes the membrane and inhibits depolarization, resulting in the failure of a propagated action potential and subsequent conduction blockade.

References

[1] Elig A. Biochim Biophys Acta, 1987, 899(2), 196-204.
[2] Strichartz G. Sthesiology, 1976, 45(4), 421-441.

Synonyms

4-Quinolinecarboxamide, 2-butoxy-N-[2-(diethylamino)ethyl]-, hydrochloride (1:1)

Cinchoninamide, 2-butoxy-N-[2-(diethylamino)ethyl]-, monohydrochloride

4-Quinolinecarboxamide, 2-butoxy-N-[2-(diethylamino)ethyl]-, monohydrochloride

Benzolin (local anesthetic)

2-n-Butoxy-N-(2-diethylaminoethyl)cinchoninamide hydrochloride

2-Butoxy-N-(2-diethylaminoethyl)cinchoninamide hydrochloride

2-Butoxy-N-(2-diethylaminoethyl)cinchoninic acid amide hydrochloride

Cinchocaine hydrochloride

Cinchocainium chloride

Dibucaine hydrochloride

Nupercaine hydrochloride

Percaine

Sovcaine

Cincaine chloride

Benzolin

Sovcain

Percain

Percamin S

Cincaine

2-Butoxy-N-(2-(diethylamino)ethyl)quinoline-4-carboxamide hydrochloride