[CAS NO. 96020-91-6] Eflornithine (MDL-71782) hydrochloride hydrate
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PRODUCTS SPECIFICATIONS [96020-91-6]
Store
Catalog
SLK-S4582
Brand
Selleck
CAS
96020-91-6
DESCRIPTION [96020-91-6]
Overview
| MDL | MFCD00242734 |
|---|---|
| Molecular Weight | 236.64 |
| Molecular Formula | C6H12F2N2O2.HCl.H2O |
| SMILES | C(CCCN)(C(F)F)(C(O)=O)N.Cl.O |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 4.2258 mL | 21.1291 mL | 42.2583 mL |
| 5 mM | 0.8452 mL | 4.2258 mL | 8.4517 mL |
| 10 mM | 0.4226 mL | 2.1129 mL | 4.2258 mL |
| 50 mM | 0.0845 mL | 0.4226 mL | 0.8452 mL |
Description
Eflornithine (Difluoromethylornithine, DFMO, MDL-71782, RMI-71782, α-difluoromethylornithine) hydrochloride hydrate inhibits by the selective, irreversible inhibition of . A chemoprotective agent that blocks angiogenesis. Its biological half-life is 8 hours.
Targets
| Orn decarboxylase [2] |
In vitro
When cultured cells are treated with α-difluoromethyl-Orn, an inhibitor of polyamine biosynthesis, production of hydrogen peroxide is suppressed and programmed cell death did not occur.
References
Synonyms
Ornithine, 2-(difluoromethyl)-, hydrochloride, hydrate (1:1:1)
DL-Ornithine, 2-(difluoromethyl)-, monohydrochloride, monohydrate
Ornithine, 2-(difluoromethyl)-, monohydrochloride, monohydrate
2,5-Diamino-2-(difluoromethyl)pentanoic acid hydrate hydrochloride
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