[CAS NO. 202409-33-4] Etoricoxib
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PRODUCTS SPECIFICATIONS [202409-33-4]
Store
Catalog
SLK-S4651
Brand
Selleck
CAS
202409-33-4
DESCRIPTION [202409-33-4]
Overview
| MDL | MFCD06797512 |
|---|---|
| Molecular Weight | 358.84 |
| Molecular Formula | C18H15ClN2O2S |
| SMILES | ClC1=CC(=C(N=C1)C=2C=CC(C)=NC2)C3=CC=C(S(C)(=O)=O)C=C3 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.7868 mL | 13.9338 mL | 27.8676 mL |
| 5 mM | 0.5574 mL | 2.7868 mL | 5.5735 mL |
| 10 mM | 0.2787 mL | 1.3934 mL | 2.7868 mL |
| 50 mM | 0.0557 mL | 0.2787 mL | 0.5574 mL |
Description
Etoricoxib (Arcoxia, MK-663, MK-0663, Tauxib, Algix, Nucoxia) is a new selective inhibitor with anti-inflammatory, antipyretic, analgesic, and potential antineoplastic properties.
Targets
| COX-2 [1] |
In vivo
The preferential cyclooxygenase-2 inhibitor etoricoxib significantly reduces the anticonvulsant action of phenytoin and significantly increases the beneficial action of diazepam against maximal electroshock and pentylenetetrazole-induced convulsions in a mouse model. Etoricoxib has the potential to act as an anti-apoptotic and anti- proliferative agent in the colon.
References
Synonyms
2,3′-Bipyridine, 5-chloro-6′-methyl-3-[4-(methylsulfonyl)phenyl]-
5-Chloro-6′-methyl-3-[4-(methylsulfonyl)phenyl]-2,3′-bipyridine
Etoricoxib
MK 663
MK 0663
Arcoxia
Torcoxia
Kingcox
Etocox
Etobrix
Etoxib
Etropain
Algix
Tauxib
Nucoxia
Etosaid
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