[CAS NO. 236395-14-5] Eslicarbazepine Acetate

Name: Eslicarbazepine Acetate
Brand: Arctom Scientific
SKU: SLK-S4657

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PRODUCTS SPECIFICATIONS [236395-14-5]

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Catalog

SLK-S4657

Brand

Selleck

CAS

236395-14-5

DESCRIPTION [236395-14-5]

Overview

MDL	-
Molecular Weight	296.32
Molecular Formula	C17H16N2O3
SMILES	O(C(C)=O)[C@@H]1C=2C(N(C(N)=O)C=3C(C1)=CC=CC3)=CC=CC2

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	3.3747 mL	16.8737 mL	33.7473 mL
5 mM	0.6749 mL	3.3747 mL	6.7495 mL
10 mM	0.3375 mL	1.6874 mL	3.3747 mL
50 mM	0.0675 mL	0.3375 mL	0.6749 mL

Description

Eslicarbazepine Acetate (BIA 2093, Zebinix, Exalief, Stedesa, Aptiom), an antiepileptic drug, is a dual a dual Inhibitor of β-Secretase and voltage-gated sodium channel.

In vivo

Eslicarbazepine acetate(ESL) has Anticonvulsant effects on the development of latrunculin A-induced seizures and paroxysmal EEG activity. ESL may also exhibit disease-modifying effects beyond suppressing just seizure activity, possibly by altering the development of a hyperexcitable network, as evidenced by the suppressed changes in glycine, taurine, glutamate and aspartate concentrations associated with an antiepileptogenic effect.

References

[1] Sierra-Paredes G, et al. BMC Neurosci. 2014, 15:134.

Synonyms

5H-Dibenz[b,f]azepine-5-carboxamide, 10-(acetyloxy)-10,11-dihydro-, (10S)-

(10S)-10-(Acetyloxy)-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide

BIA 2-093

(S)-(-)-10-Acetoxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide

(S)-10-Acetoxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide

Eslicarbazepine acetate

Sep 0002093

Exelief

(S)-(-)-10-Acetoxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide

Aptiom

(S)-5-Carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl acetate

Zebinix

Exalief