[CAS NO. 121-79-9] Propyl gallate

Name: Propyl gallate
Brand: Arctom Scientific
SKU: SLK-S5113

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PRODUCTS SPECIFICATIONS [121-79-9]

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Catalog

SLK-S5113

Brand

Selleck

CAS

121-79-9

DESCRIPTION [121-79-9]

Overview

MDL	MFCD00002196
Molecular Weight	212.20
Molecular Formula	C10H12O5
SMILES	C(OCCC)(=O)C1=CC(O)=C(O)C(O)=C1

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	4.7125 mL	23.5627 mL	47.1254 mL
5 mM	0.9425 mL	4.7125 mL	9.4251 mL
10 mM	0.4713 mL	2.3563 mL	4.7125 mL
50 mM	0.0943 mL	0.4713 mL	0.9425 mL

Description

Propyl gallate (Gallic acid propyl esterZ, n-Propyl gallate) is an antioxidant used in foods especially animal fats and vegetable oils, also in a wide variety of cosmetics and beauty care products.

In vitro

Propyl gallate (PG) could modulate heme oxygenase-1 (HO-1) activation and decrease lung cancer cell survival. Propyl gallate also induces apoptosis in human leukemia cells and HeLa cells by increasing reactive oxygen species (ROS) levels and glutathione (GSH) depletion. Propyl gallate inhibits the expression of MMP-2 and MMP-9 and exerts an antimigration effect on TMZ-treated U87MG cells. Propyl gallate also possesses anti-inflammatory activity via downregulation of the NF-κB pathway. Propyl gallate could reduce the proliferation and augment the chemosensitivity of a THP-1 leukemia cell line via extrinsic and intrinsic apoptotic pathways.

In vivo

In brain ischemia, Propyl gallate inhibits the activity of NF-κB, reduces COX-2 and TNF-alpha G expression, and decreases ischemic-reperfusion injury.

References

[1] Jen-Tsung Yang, et al. Journal of Immunology Research. 2017.

Synonyms

Benzoic acid, 3,4,5-trihydroxy-, propyl ester

Gallic acid, propyl ester

Nipa 49

Nipagallin P

Progallin P

Propyl gallate

n-Propyl 3,4,5-trihydroxybenzoate

Tenox PG

n-Propyl gallate

Propyl 3,4,5-trihydroxybenzoate

PG

Nipanox S 1

Gallic acid n-propyl ester

E 310

NSC 2626

Hemostyptin

Marupi Gallate

Antioxidant PG

GAPR

3,4,5-Trihydroxybenzoic acid propyl ester