[CAS NO. 501-30-4] Kojic acid
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PRODUCTS SPECIFICATIONS [501-30-4]
Store
Catalog
SLK-S5174
Brand
Selleck
CAS
501-30-4
DESCRIPTION [501-30-4]
Overview
| MDL | MFCD00006580 |
|---|---|
| Molecular Weight | 142.11 |
| Molecular Formula | C6H6O4 |
| SMILES | C(O)C1=CC(=O)C(O)=CO1 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 7.0368 mL | 35.1840 mL | 70.3680 mL |
| 5 mM | 1.4074 mL | 7.0368 mL | 14.0736 mL |
| 10 mM | 0.7037 mL | 3.5184 mL | 7.0368 mL |
| 50 mM | 0.1407 mL | 0.7037 mL | 1.4074 mL |
Description
Kojic acid is a fungal metabolite that inhibits with an IC50 value of 30.6 µM for mushroom tyrosinase. It is a synthetic intermediate used for production of food additives.
Targets
| Tyrosinase [2] |
| 0.28 mM |
In vitro
Kojic acid (KA) acts as a good chelator of transition metal ions such as Cu2+ and Fe3+ and a scavenger of free radicals. Kojic acid shows a competitive inhibitory effect on the monophenolase activity and a mixed inhibitory effect on the diphenolase activity of mushroom tyrosinase. Kojic acid could highly protect Chinese hamster ovary (CHO) cells against ionizing radiation with low toxicity.
In vivo
Kojic acid exerts its radioprotective effects on lethal or sub-lethal irradiation induced damages in mice.
References
Synonyms
4H-Pyran-4-one, 5-hydroxy-2-(hydroxymethyl)-
5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one
Kojic acid
5-Hydroxy-2-hydroxymethyl-4-pyrone
2-(Hydroxymethyl)-5-hydroxy-4H-pyran-4-one
NSC 1942
5-Hydroxy-2-(hydroxymethyl)-4H-pyranone
5-Hydroxy-2-hydroxymethylpyran-4-one
5-Hydroxy-2-hydroxymethyl-1,4-pyrone
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