[CAS NO. 5355-16-8] Diaveridine
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PRODUCTS SPECIFICATIONS [5355-16-8]
Store
Catalog
SLK-S5200
Brand
Selleck
CAS
5355-16-8
DESCRIPTION [5355-16-8]
Overview
| MDL | MFCD00057349 |
|---|---|
| Molecular Weight | 260.29 |
| Molecular Formula | C13H16N4O2 |
| SMILES | C(C1=CC(OC)=C(OC)C=C1)C=2C(N)=NC(N)=NC2 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 3.8419 mL | 19.2093 mL | 38.4187 mL |
| 5 mM | 0.7684 mL | 3.8419 mL | 7.6837 mL |
| 10 mM | 0.3842 mL | 1.9209 mL | 3.8419 mL |
| 50 mM | 0.0768 mL | 0.3842 mL | 0.7684 mL |
Description
Diaveridine (AI3-23935, CCRIS-3784) is coccidiostat with anti-parasitic activity and also a inhibitor preventing folic acid synthesis in species of Pneumocystis.
Targets
| DHFR [1] |
In vitro
Diaveridine (DVD) is a pyrimethamine analogue, a folic acid antagonist. It is also used as an antibacterial agent, especially for the respiratory and gastrointestinal tract infections in humans and animals. Diaveridine is genotoxic in mammalian cells in vitro and in vivo.
In vivo
Acute tests indicate that the diaveridine has a high LD50 value and suggests a wide margin of safety for therapeutic doses.
Synonyms
2,4-Pyrimidinediamine, 5-[(3,4-dimethoxyphenyl)methyl]-
Pyrimidine, 2,4-diamino-5-veratryl-
5-[(3,4-Dimethoxyphenyl)methyl]-2,4-pyrimidinediamine
2,4-Diamino-5-(3,4-dimethoxybenzyl)pyrimidine
2,4-Diamino-5-veratrylpyrimidine
Diaveridine
Diaveridin
EGIS 5645
NSC 408735
BW 49-210
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