[CAS NO. 923288-95-3] Nilotinib hydrochloride
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PRODUCTS SPECIFICATIONS [923288-95-3]
Store
Catalog
SLK-S5205
Brand
Selleck
CAS
923288-95-3
DESCRIPTION [923288-95-3]
Overview
| MDL | MFCD16038432 |
|---|---|
| Molecular Weight | 565.98 |
| Molecular Formula | C28H22F3N7O.HCl |
| SMILES | O=C(NC1=CC(C(F)(F)F)=CC(N2C=C(C)N=C2)=C1)C3=CC=C(C)C(NC4=NC=CC(C5=CC=CN=C5)=N4)=C3.[H]Cl |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 1.7668 mL | 8.8342 mL | 17.6685 mL |
| 5 mM | 0.3534 mL | 1.7668 mL | 3.5337 mL |
| 10 mM | 0.1767 mL | 0.8834 mL | 1.7668 mL |
| 50 mM | 0.0353 mL | 0.1767 mL | 0.3534 mL |
Description
Nilotinib hydrochloride (AMN-107) is the hydrochloride salt form of nilotinib, an orally bioavailable tyrosine kinase inhibitor with antineoplastic activity.
Targets
| Bcr-Abl [1] (Murine myeloid progenitor cells) |
| <30 nM |
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