[CAS NO. 976-71-6]  Canrenone

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PRODUCTS SPECIFICATIONS [976-71-6]

Store
Catalog
SLK-S5273
Brand
Selleck
CAS
976-71-6

DESCRIPTION [976-71-6]

Overview

MDL-
Molecular Weight340.46
Molecular FormulaC22H28O3
SMILESC[C@@]12[C@]3(CC[C@]1([C@]4([C@](CC2)([C@]5(C)C(C=C4)=CC(=O)CC5)[H])[H])[H])OC(=O)CC3

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.9372 mL14.6860 mL29.3720 mL
5 mM0.5874 mL2.9372 mL5.8744 mL
10 mM0.2937 mL1.4686 mL2.9372 mL
50 mM0.0587 mL0.2937 mL0.5874 mL

Description

Canrenone (Aldadiene, SC-9376, RP-11614, 6,7-Dehydro-7α-desthioacetylspironolactone), a cardiovascular drug, a sort of steroid, is spironolactone's major metabolite and has been widely used as a nonselective antagonist clinically to treat heart failure, high blood pressure, edema, liver ascites, and other cardiovascular diseases.

Synonyms

Pregna-4,6-diene-21-carboxylic acid, 17-hydroxy-3-oxo-, γ-lactone, (17α)-
17α-Pregna-4,6-diene-21-carboxylic acid, 17-hydroxy-3-oxo-, γ-lactone
Spiro[17H-cyclopenta[a]phenanthrene-17,2′(5′H)-furan], pregna-4,6-diene-21-carboxylic acid deriv.
Canrenone
17α-(2-Carboxyethyl)-17β-hydroxyandrosta-4,6-dien-3-one lactone
17-Hydroxy-3-oxo-17α-pregna-4,6-diene-21-carboxylic acid γ-lactone
3-(17β-Hydroxy-3-oxoandrosta-4,6-dien-17α-yl)propionic acid γ-lactone
Phanurane
Aldadiene
SC 9376
3′-(3-Oxo-17β-hydroxyandrosta-4,6-dien-17α-yl)-propionic acid lactone
Spirolactone SC 14266
3-(17β-Hydroxy-3-oxoandrosta-4,6-dien-17α-yl)propionic acid lactone
17-Hydroxy-3-oxo-17α-pregna-4,6-diene-21-carboxylic acid lactone
3-(3-Oxo-17β-hydroxy-4,6-androstadien-17α-yl)propionic acid γ-lactone
11614 R.P.
20-Spiroxa-4,6-diene-3,21-dione
17β-Hydroxy-3-oxopregna-4,6-diene-21-carboxylic acid
NSC 261713