[CAS NO. 134523-00-5]  Atorvastatin

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PRODUCTS SPECIFICATIONS [134523-00-5]

Store
Catalog
SLK-S5715
Brand
Selleck
CAS
134523-00-5

DESCRIPTION [134523-00-5]

Overview

MDLMFCD00899261
Molecular Weight558.64
Molecular FormulaC33H35FN2O5
SMILESC(NC1=CC=CC=C1)(=O)C=2C(=C(N(CC[C@H](C[C@H](CC(O)=O)O)O)C2C(C)C)C3=CC=C(F)C=C3)C4=CC=CC=C4

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Description

Atorvastatin is a lipid lowering agent. It is a competitive inhibitor of , the rate-determining enzyme in cholesterol biosynthesis via the mevalonate pathway. Atorvastatin activates .

In vitro

Atorvastatin, one of the statins, inhibits the c-Myc pathway in chronic myeloid leukemia (CML) cells, demonstrating that c-Myc is a target of statins.


Synonyms

1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, (βRR)-
1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, [R-(R*,R*)]-
RR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid
RR)-2-(p-Fluorophenyl)-β,δ-dihydroxy-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrole-1-heptanoic acid
Atorvastatin
Cardyl
(3R,5R)-7-[2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-phenylcarbamoylpyrrol-1-yl]-3,5-dihydroxyheptanoic acid
Atorvastatin acid
Lipilou
Ator
Atorfit 20
Atorcor
Atofast
Atorin
Alip
Statofilm
Lipinon
Atorvox
Atoris
Atrox
Atavastatin
1: PN: WO2019129231 SEQID: 2 claimed sequence