[CAS NO. 38520-57-9] N-Acetylcysteine amide
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PRODUCTS SPECIFICATIONS [38520-57-9]
Store
Catalog
SLK-S5804
Brand
Selleck
CAS
38520-57-9
DESCRIPTION [38520-57-9]
Overview
| MDL | MFCD01696115 |
|---|---|
| Molecular Weight | 162.21 |
| Molecular Formula | C5H10N2O2S |
| SMILES | [C@@H](NC(C)=O)(C(N)=O)CS |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 6.1648 mL | 30.8242 mL | 61.6485 mL |
| 5 mM | 1.2330 mL | 6.1648 mL | 12.3297 mL |
| 10 mM | 0.6165 mL | 3.0824 mL | 6.1648 mL |
| 50 mM | 0.1233 mL | 0.6165 mL | 1.2330 mL |
Description
N-acetylcysteine amide is a membrane penetrating antioxidant with anti-inflamatory activity through regulation of activation of NF-κB and HIF-1α as well as modulation of ROS.
In vitro
The antioxidant N-acetylcysteine (NAC) blocks erastin-induced or RSL3-induced cell death in Nupr1 mPDAC cells, an effect that is associated with decreased production or release of MDA, 8-OHdG, or HMGB1. NUPR1-knockdown PANC1 cells exhibits increased MDA, 8-OHdG, and HMGB1 release during ferroptotic cell death, which can be reversed by the addition of NAC.
References
Synonyms
Propanamide, 2-(acetylamino)-3-mercapto-, (2R)-
Propanamide, 2-(acetylamino)-3-mercapto-, (R)-
(2R)-2-(Acetylamino)-3-mercaptopropanamide
N-Acetyl-L-cysteinamide
N-Acetylcysteine amide
(2R)-2-Acetamido-3-sulfanylpropanamide
(R)-2-Acetamido-3-mercaptopropanamide
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