[CAS NO. 928672-86-0]  Canagliflozin hemihydrate

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PRODUCTS SPECIFICATIONS [928672-86-0]

Store
Catalog
SLK-S5901
Brand
Selleck
CAS
928672-86-0

DESCRIPTION [928672-86-0]

Overview

MDLMFCD28975933
Molecular Weight907.05
Molecular FormulaC48H52F2O11S2
SMILESO[C@H]1[C@H](C2=CC=C(C)C(CC3=CC=C(C4=CC=C(F)C=C4)S3)=C2)O[C@H](CO)[C@@H](O)[C@@H]1O.[H]O[H].O[C@H]5[C@H](C6=CC=C(C)C(CC7=CC=C(C8=CC=C(F)C=C8)S7)=C6)O[C@H](CO)[C@@H](O)[C@@H]5O

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM1.1025 mL5.5124 mL11.0248 mL
5 mM0.2205 mL1.1025 mL2.2050 mL
10 mM0.1102 mL0.5512 mL1.1025 mL
50 mM0.0220 mL0.1102 mL0.2205 mL

Description

Canagliflozin hemihydrate is the hemihydrate form of canagliflozin, which is a inhibitor with IC50 of 2.2 nM for hSGLT2 in a cell-free assay, exhibits 413-fold selectivity over hSGLT1.

Targets

mSGLT2 [1]
(Cell-free assay)
hSGLT2 [1]
(Cell-free assay)
2 nM4.4 nM