[CAS NO. 420831-40-9]  AK 7

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PRODUCTS SPECIFICATIONS [420831-40-9]

Store
Catalog
SLK-S5914
Brand
Selleck
CAS
420831-40-9

DESCRIPTION [420831-40-9]

Overview

MDLMFCD03140195
Molecular Weight437.35
Molecular FormulaC19H21BrN2O3S
SMILESO=C(NC1=CC=CC(Br)=C1)C2=CC=CC(S(=O)(N3CCCCCC3)=O)=C2

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.2865 mL11.4325 mL22.8650 mL
5 mM0.4573 mL2.2865 mL4.5730 mL
10 mM0.2286 mL1.1432 mL2.2865 mL
50 mM0.0457 mL0.2286 mL0.4573 mL

Description

AK 7 is a brain-permeable selective inhibitor with an IC50 of 15.5 μM.

Targets

SIRT2 [1]
15.5 μM

In vitro

Treatment with AK7 increases lysine 40 (K40) acetylation of α-tubulin in neuronal cells. AK7 ameliorates alpha-synuclein toxicity in vitro.