[CAS NO. 224785-91-5] Vardenafil hydrochloride

Name: Vardenafil hydrochloride
Brand: Arctom Scientific
SKU: SLK-S5957

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PRODUCTS SPECIFICATIONS [224785-91-5]

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Catalog

SLK-S5957

Brand

Selleck

CAS

224785-91-5

DESCRIPTION [224785-91-5]

Overview

MDL	MFCD07369690
Molecular Weight	525.06
Molecular Formula	C23H33ClN6O4S
SMILES	C(CC)C=1N2C(C(=O)N=C(N2)C3=C(OCC)C=CC(S(=O)(=O)N4CCN(CC)CC4)=C3)=C(C)N1.Cl

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Concentration Volume Mass	1 mg	5 mg	10 mg
1 mM	1.9045 mL	9.5227 mL	19.0454 mL
5 mM	0.3809 mL	1.9045 mL	3.8091 mL
10 mM	0.1905 mL	0.9523 mL	1.9045 mL
50 mM	0.0381 mL	0.1905 mL	0.3809 mL

Description

Vardenafil (BAY38-9456, Levitra, Staxyn) hydrochloride is a selective, orally active, potent inhibitor of with IC50 of 0.7 nM, 11 nM and 180 nM for PDE5, PDE6 and PDE1, respectively.

Targets

PDE5 ^[1] (Cell-free assay)	PDE6 ^[1] (Cell-free assay)	PDE1 ^[1] (Cell-free assay)
0.7 nM	11 nM	180 nM

References

[1] I Saenz de Tejada, et al. Int J Impot Res. 2001 Oct;13(5):282-90.

Synonyms

Imidazo[5,1-f][1,2,4]triazin-4(1H)-one, 2-[2-ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]phenyl]-5-methyl-7-propyl-, hydrochloride (1:1)

Piperazine, 1-[[3-(1,4-dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]-4-ethyl-, monohydrochloride

Levitra

Vardenafil hydrochloride