[CAS NO. 219639-75-5]  PMX-53

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PRODUCTS SPECIFICATIONS [219639-75-5]

Store
Catalog
SLK-S6239
Brand
Selleck
CAS
219639-75-5

DESCRIPTION [219639-75-5]

Overview

MDL-
Molecular Weight896.09
Molecular FormulaC47H65N11O7
SMILES-

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM1.1160 mL5.5798 mL11.1596 mL
5 mM0.2232 mL1.1160 mL2.2319 mL
10 mM0.1116 mL0.5580 mL1.1160 mL
50 mM0.0223 mL0.1116 mL0.2232 mL

Description

PMX-53 is a potent antagonist and inhibits C5a-induced neutrophil myeloperoxidase release and chemotaxis with IC50 values of 22 nM and 75 nM, respectively. PMX-53 is also an agonist of .

Targets

CD88 [1]MrgX2 [1]