[CAS NO. 1000025-07-9]  Vadadustat

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PRODUCTS SPECIFICATIONS [1000025-07-9]

Store
Catalog
SLK-S6490
Brand
Selleck
CAS
1000025-07-9

DESCRIPTION [1000025-07-9]

Overview

MDL-
Molecular Weight306.70
Molecular FormulaC14H11ClN2O4
SMILESOC1=CC(=CN=C1C(NCC(O)=O)=O)C2=CC(Cl)=CC=C2

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM3.2605 mL16.3026 mL32.6052 mL
5 mM0.6521 mL3.2605 mL6.5210 mL
10 mM0.3261 mL1.6303 mL3.2605 mL
50 mM0.0652 mL0.3261 mL0.6521 mL

Description

Vadadustat (AKB-6548, B-506, PG-1016548) is a novel, titratable, oral inhibitor.

Targets

PH2 [1]FIH(factor inhibiting HIF) [1]
0.029 μM29 μM

In vitro

Vadadustat works by active site iron chelating mechanisms in terms of inhibiting isolated PHD2.


Synonyms

Glycine, N-[[5-(3-chlorophenyl)-3-hydroxy-2-pyridinyl]carbonyl]-
N-[[5-(3-Chlorophenyl)-3-hydroxy-2-pyridinyl]carbonyl]glycine
PG 1016548
Vadadustat
AKB 6548
2-[[[5-(3-Chlorophenyl)-3-hydroxypyridin-2-yl]carbonyl]amino]acetic acid