Overview
| MDL | - |
|---|
| Molecular Weight | 296.75 |
|---|
| Molecular Formula | C16H13ClN4 |
|---|
| SMILES | NC1N=CC(C2C=NC(N)=C(C3C=CC(Cl)=CC=3)C=2)=CC=1 |
|---|
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg |
| 1 mM | 3.3698 mL | 16.8492 mL | 33.6984 mL |
| 5 mM | 0.6740 mL | 3.3698 mL | 6.7397 mL |
| 10 mM | 0.3370 mL | 1.6849 mL | 3.3698 mL |
| 50 mM | 0.0674 mL | 0.3370 mL | 0.6740 mL |
Description
PF-6260933 (PF-06260933) is a potent inhibitor of with an IC50 of 3.7 nM, possessing excellent kinome selectivity.
In vitro
PF-6260933 demonstrates good physicochemical properties as well as moderate human liver microsomal (HLM) clearance.