[CAS NO. 1811510-56-1]  PF-6260933

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PRODUCTS SPECIFICATIONS [1811510-56-1]

Store
Catalog
SLK-S6499
Brand
Selleck
CAS
1811510-56-1

DESCRIPTION [1811510-56-1]

Overview

MDL-
Molecular Weight296.75
Molecular FormulaC16H13ClN4
SMILESNC1N=CC(C2C=NC(N)=C(C3C=CC(Cl)=CC=3)C=2)=CC=1

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM3.3698 mL16.8492 mL33.6984 mL
5 mM0.6740 mL3.3698 mL6.7397 mL
10 mM0.3370 mL1.6849 mL3.3698 mL
50 mM0.0674 mL0.3370 mL0.6740 mL

Description

PF-6260933 (PF-06260933) is a potent inhibitor of with an IC50 of 3.7 nM, possessing excellent kinome selectivity.

Targets

MAP4K4 [1]
3.7 nM

In vitro

PF-6260933 demonstrates good physicochemical properties as well as moderate human liver microsomal (HLM) clearance.