[CAS NO. 1186206-79-0] ALW II-41-27

Name: ALW II-41-27
Brand: Arctom Scientific
SKU: SLK-S6515

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PRODUCTS SPECIFICATIONS [1186206-79-0]

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Catalog

SLK-S6515

Brand

Selleck

CAS

1186206-79-0

MDL	MFCD25372028
Molecular Weight	607.69
Molecular Formula	C32H32F3N5O2S
SMILES	CC1=C(NC(C2=CC(C3=CC=CS3)=CN=C2)=O)C=C(C(NC4=CC=C(CN5CCN(CC)CC5)C(C(F)(F)F)=C4)=O)C=C1

For research use only.

3 years,-20°C,powder
1 years,-80°C,in solvent

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

ALW II-41-27 (compound 7) is a potent inhibitor of with Kd of 12 nM for EphA2.

EphA2 ^[1]
(Cell-free assay)

12 nM(Kd)

After ALW-II-41-27 (EPHA2 inhibitor) treatment (0.5 μM) in GM for 12 h, the phosphorylation of EPHA2 is decreased (P < 0.05).