[CAS NO. 1443246-62-5]  ML-297

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PRODUCTS SPECIFICATIONS [1443246-62-5]

Store
Catalog
SLK-S6559
Brand
Selleck
CAS
1443246-62-5

DESCRIPTION [1443246-62-5]

Overview

MDLMFCD27977571
Molecular Weight328.32
Molecular FormulaC17H14F2N4O
SMILESO=C(NC1=CC(C)=NN1C2=CC=CC=C2)NC3=CC=C(F)C(F)=C3

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM3.0458 mL15.2290 mL30.4581 mL
5 mM0.6092 mL3.0458 mL6.0916 mL
10 mM0.3046 mL1.5229 mL3.0458 mL
50 mM0.0609 mL0.3046 mL0.6092 mL

Description

ML-297 (VU 0456810, CID 56642816) is a potent and selective activator of channel with EC50 of 0.16 μM and 1.8 μM for GIRK1/2 and GIRK1/4, respectively. ML-297 is potential for the treatment of epilepsy.

Targets

GIRK1/2 [1]
(Cell-free assay)
GIRK1/4 [1]
(Cell-free assay)
0.16 μM1.8 μM