[CAS NO. 314054-00-7] C-176
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PRODUCTS SPECIFICATIONS [314054-00-7]
Store
Catalog
SLK-S6575
Brand
Selleck
CAS
314054-00-7
DESCRIPTION [314054-00-7]
Overview
| MDL | MFCD00784208 |
|---|---|
| Molecular Weight | 358.09 |
| Molecular Formula | C11H7IN2O4 |
| SMILES | O=C(C1=CC=C([N+]([O-])=O)O1)NC2=CC=C(I)C=C2 |
For research use only.
Storage
3 years,-20°C,powder
1 years,-80°C,in solvent
1 years,-80°C,in solvent
Shipping
Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Preparing Stock Solutions
| 1 mg | 5 mg | 10 mg | |
| 1 mM | 2.7926 mL | 13.9630 mL | 27.9259 mL |
| 5 mM | 0.5585 mL | 2.7926 mL | 5.5852 mL |
| 10 mM | 0.2793 mL | 1.3963 mL | 2.7926 mL |
| 50 mM | 0.0559 mL | 0.2793 mL | 0.5585 mL |
Description
STING inhibitor C-176 is a potent, small-molecule inhibitor of , a central signaling component of the intracellular DNA sensing pathway.
Targets
| STING [1] |
In vitro
C-176 strongly reduces STING-mediated, but not RIG-I- or TBK1-mediated, IFNβ reporter activity. It directly targets mouse STING (mmSTING) but not human STING (hsSTING).
References
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